His main research concerns Immunology, Indoleamine 2,3-dioxygenase, T cell, Immune system and Cell biology. His Immunotherapy, Immune tolerance, Antigen and Antigen-presenting cell study, which is part of a larger body of work in Immunology, is frequently linked to Population, bridging the gap between disciplines. His Indoleamine 2,3-dioxygenase research includes elements of Dendritic cell, Immunosuppression, Melanoma, Dioxygenase and FOXP3.
His T cell study incorporates themes from Inflammation, Receptor, Cancer research and Fetus. His Immune system research is multidisciplinary, incorporating perspectives in Myeloid and Tumor progression, Cancer. In Cell biology, he works on issues like CD28, which are connected to Interferon gamma and Enzyme activator.
David H. Munn mainly focuses on Immunology, Immune system, Indoleamine 2,3-dioxygenase, Cancer research and T cell. His study in Immunology is interdisciplinary in nature, drawing from both Cytotoxic T cell and Cell biology. His Immune system research is multidisciplinary, incorporating elements of Inflammation, Proinflammatory cytokine and Cancer.
His Indoleamine 2,3-dioxygenase research includes themes of Acquired immune system, Dendritic cell, Immunosuppression, CpG Oligodeoxynucleotide and Kynurenine. His Melanoma study in the realm of Cancer research interacts with subjects such as Population. The T cell study combines topics in areas such as Biochemistry and Transplantation.
David H. Munn focuses on Cancer research, Immune system, Immunology, Immunotherapy and T cell. He interconnects Inflammation, Transcription factor, Cytokine and Indoleamine 2,3-dioxygenase in the investigation of issues within Immune system. The concepts of his Indoleamine 2,3-dioxygenase study are interwoven with issues in Kynurenine and Antigen-presenting cell.
His Immunology study integrates concerns from other disciplines, such as Carcinogenesis and Melanoma. The study incorporates disciplines such as Tumor necrosis factor alpha, Molecular biology and Antigen in addition to Immunotherapy. His research in T cell intersects with topics in Haematopoiesis, Effector, Cell biology and CD8.
David H. Munn spends much of his time researching Immunology, Immune system, Cancer research, Tumor microenvironment and Immunotherapy. His Immunology study often links to related topics such as Carcinogenesis. He has included themes like Inflammation, Transcription factor and Indoleamine 2,3-dioxygenase in his Immune system study.
His work is dedicated to discovering how Cancer research, Proinflammatory cytokine are connected with Small interfering RNA and Macrophage polarization and other disciplines. Within one scientific family, David H. Munn focuses on topics pertaining to T cell under Tumor microenvironment, and may sometimes address concerns connected to LRP6, Frizzled, LRP5 and Wnt signaling pathway. His Immunotherapy research incorporates themes from Myeloid and Antigen-presenting cell.
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Prevention of allogeneic fetal rejection by tryptophan catabolism
David H. Munn;Min Zhou;John T. Attwood;Igor Bondarev.
Science (1998)
IDO expression by dendritic cells: tolerance and tryptophan catabolism.
Andrew L. Mellor;David H. Munn.
Nature Reviews Immunology (2004)
INHIBITION OF T CELL PROLIFERATION BY MACROPHAGE TRYPTOPHAN CATABOLISM
David H. Munn;Ebrahim Shafizadeh;John T. Attwood;Igor Bondarev.
Journal of Experimental Medicine (1999)
Activation of Gpr109a, Receptor for Niacin and the Commensal Metabolite Butyrate, Suppresses Colonic Inflammation and Carcinogenesis
Nagendra Singh;Ashish Gurav;Sathish Sivaprakasam;Evan Brady.
Immunity (2014)
Potential Regulatory Function of Human Dendritic Cells Expressing Indoleamine 2,3-Dioxygenase
David H. Munn;Madhav D. Sharma;Jeffrey R. Lee;Kanchan G. Jhaver.
Science (2002)
GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase.
David H. Munn;Madhav D. Sharma;Babak Baban;Heather P. Harding.
Immunity (2005)
Indoleamine 2,3-dioxygenase and tumor-induced tolerance.
David H. Munn;Andrew L. Mellor.
Journal of Clinical Investigation (2007)
Expression of indoleamine 2,3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes
David H. Munn;Madhav D. Sharma;Deyan Hou;Babak Baban.
Journal of Clinical Investigation (2004)
Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase
Madhav D. Sharma;Babak Baban;Phillip Chandler;De Yan Hou.
Journal of Clinical Investigation (2007)
Indoleamine 2,3 dioxygenase and metabolic control of immune responses
David H. Munn;Andrew L. Mellor.
Trends in Immunology (2013)
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