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Letícia V. Costa-Lotufo

Letícia V. Costa-Lotufo

D-Index & Metrics

Biology and Biochemistry

D-Index
65
Citations
13228
World Ranking
9275
National Ranking
35

Overview

Letícia V. Costa-Lotufo is affiliated with the Universidade de São Paulo in Brazil and has contributed extensively to the fields of biochemistry, genetics, molecular biology, and medicine. Their research output encompasses a range of subfields, including molecular biology, pharmacology, organic chemistry, hematology, and oncology.

The scientist's work focuses on several main topics such as microbial natural products and biosynthesis, acute myeloid leukemia research, histone deacetylase inhibitors, protein degradation and inhibitors, metabolomics and mass spectrometry studies, cancer therapeutics and mechanisms, and marine sponges and natural products.

Frequent collaborators include João Agostinho Machado-Neto, Paula C. Jimenez, Keli Lima, Paula Rezende-Teixeira, and Norberto Peporine Lopes. The venues most commonly featuring their publications are Hematology Transfusion and Cell Therapy, bioRxiv (Cold Spring Harbor Laboratory), Zenodo (CERN European Organization for Nuclear Research), Chemistry & Biodiversity, and Veterinary and Comparative Orthopaedics and Traumatology.

Recent papers authored by Letícia V. Costa-Lotufo include:

  • Mass spectrometry-based metabolomics in microbiome investigations, 2021, Nature Reviews Microbiology
  • What can we learn from commercial insecticides? Efficacy, toxicity, environmental impacts, and future developments, 2022, Environmental Pollution
  • A community resource for paired genomic and metabolomic data mining, 2021, Nature Chemical Biology
  • microbeMASST: a taxonomically informed mass spectrometry search tool for microbial metabolomics data, 2024, Nature Microbiology
  • DNA damaging agents and DNA repair: From carcinogenesis to cancer therapy, 2020, Cancer Genetics

Letícia V. Costa-Lotufo's research spans both experimental and analytical approaches, with a notable emphasis on mass spectrometry and metabolomics applied to microbiome investigations and microbial metabolomics data. Their contributions to understanding DNA damage and repair mechanisms link molecular biology insights to potential cancer therapies.

The scientist's extensive publication record is reflected in frequent contributions to specialized journals and preprint servers, highlighting active engagement with both foundational research and emerging scientific discussions.

Best Publications

  • Studies of the anticancer potential of plants used in Bangladeshi folk medicine.

    Letícia Veras Costa-Lotufo;Mahmud Tareq Hassan Khan;Arjumand Ather;Diego Veras Wilke

  • Overview of the therapeutic potential of piplartine (piperlongumine).

    Daniel P. Bezerra;Claudia Pessoa;Manoel O. de Moraes;Nicolau Saker-Neto

  • Mass spectrometry-based metabolomics in microbiome investigations.

    Anelize Bauermeister;Helena Mannochio-Russo;Letícia V Costa-Lotufo;Alan K Jarmusch

  • In vivo growth-inhibition of Sarcoma 180 by piplartine and piperine, two alkaloid amides from Piper.

    D.P. Bezerra;F.O. Castro;A.P.N.N. Alves;C. Pessoa

  • Cytotoxic activity of Brazilian Cerrado plants used in traditional medicine against cancer cell lines

    Mariana Laundry de Mesquita;José Elias de Paula;Cláudia Pessoa;Manoel Odorico de Moraes

  • The cytotoxic and embryotoxic effects of kaurenoic acid, a diterpene isolated from Copaifera langsdorffii oleo-resin.

    L.V. Costa-Lotufo;G.M.A. Cunha;P.A.M. Farias;G.S.B. Viana

  • Antitumor properties of a sulfated polysaccharide from the red seaweed Champia feldmannii (Diaz‐Pifferer)

    Kézia O. A. L. Lins;Daniel P. Bezerra;Ana Paula N. N. Alves;Nylane M. N. Alencar

  • In vitro and in vivo antitumor effect of 5-FU combined with piplartine and piperine

    Daniel P. Bezerra;Fernanda O. de Castro;Ana Paula N. N. Alves;Cláudia Pessoa

  • Piplartine induces inhibition of leukemia cell proliferation triggering both apoptosis and necrosis pathways.

    Daniel Pereira Bezerra;Gardenia Carmen Gadelha Militão;Fernanda Oliveira de Castro;Cláudia Pessoa

  • Genotoxicity evaluation of kaurenoic acid, a bioactive diterpenoid present in Copaiba oil.

    B.C. Cavalcanti;L.V. Costa-lotufo;M.O. Moraes;R.R. Burbano

  • Contamination of port zone sediments by metals from Large Marine Ecosystems of Brazil

    Lucas M. Buruaem;Marcos A. Hortellani;Jorge E. Sarkis;Leticia V. Costa-Lotufo

  • In vivo growth-inhibition of Sarcoma 180 tumor by alginates from brown seaweed Sargassum vulgare

    Alessandra Paula Alves de Sousa;Márcia Rocha Torres;Cláudia Pessoa;Manoel Odorico de Moraes

  • Folk uses and pharmacological properties of Casearia sylvestris: a medicinal review

    Paulo Michel P. Ferreira;Leticia V. Costa-Lotufo;Manoel O. Moraes;Francisco W.A. Barros

  • Biological activity in extracts of ascidians (Tunicata, Ascidiacea) from the northeastern Brazilian coast

    Paula C Jimenez;Sérgio C Fortier;Tito M.C Lotufo;Cláudia Pessoa

  • Synthesis and potent antitumor activity of new arylamino derivatives of nor-β-lapachone and nor-α-lapachone

    Eufrânio N. da Silva Júnior;Maria Cecília B.V. de Souza;Antônio V. Pinto;Maria do Carmo F.R. Pinto

  • Cytotoxic, Trypanocidal Activities and Physicochemical Parameters of nor-β-Lapachone-based 1,2,3-Triazoles

    N Eufrânio;Maria Aline;B. F. de Moura;Antonio V. Pinto

  • Antiproliferative activity of pristimerin isolated from Maytenus ilicifolia (Celastraceae) in human HL-60 cells.

    Patricia Marçal da Costa;Paulo Michel Pinheiro Ferreira;Vanderlan da Silva Bolzani;Maysa Furlan

  • 3-Arylamino and 3-Alkoxy-nor-β-lapachone Derivatives: Synthesis and Cytotoxicity against Cancer Cell Lines

    Eufrânio N. Da Silva;Clara F. De Deus;Bruno C. Cavalcanti;Cláudia Pessoa

  • Genotoxic effects of aluminum chloride in cultured human lymphocytes treated in different phases of cell cycle

    P.D.L. Lima;D.S. Leite;M.C. Vasconcellos;B.C. Cavalcanti

  • In-vitro and in-vivo antitumour activity of physalins B and D from Physalis angulata.

    Hemerson Iury Ferreira Magalhães;Márcia Rocha Torres;Letícia Veras Costa-Lotufo;Manoel Odorico De Moraes

Frequent Co-Authors

Cláudia Pessoa
Cláudia Pessoa Universidade Federal do Ceará
Manoel Odorico de Moraes
Manoel Odorico de Moraes Universidade Federal do Ceará
Norberto Peporine Lopes
Norberto Peporine Lopes Universidade de São Paulo
João Antonio Pêgas Henriques
João Antonio Pêgas Henriques University of Caxias Do Sul
Denis Moledo de Souza Abessa
Denis Moledo de Souza Abessa Sao Paulo State University
Vitor F. Ferreira
Vitor F. Ferreira Fluminense Federal University
William Fenical
William Fenical University of California, San Diego
Susana Loureiro
Susana Loureiro University of Aveiro
Márcia Caruso Bícego
Márcia Caruso Bícego Universidade de São Paulo
Jairo Kenupp Bastos
Jairo Kenupp Bastos Universidade de São Paulo

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