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Solange L. de Castro

Solange L. de Castro

D-Index & Metrics

Biology and Biochemistry

D-Index
55
Citations
10269
World Ranking
15115
National Ranking
79

Overview

Solange L. de Castro is affiliated with the Oswaldo Cruz Foundation in Brazil. Their research spans multiple disciplines, primarily focusing on materials science and medicine. Within these broad areas, their work engages deeply with materials chemistry and epidemiology, alongside organic chemistry, public health, environmental and occupational health, and toxicology.

The scientific contributions of Solange L. de Castro include studies on crystallization and solubility, with a special emphasis on X-ray diffraction in crystallography. Their research also extensively covers topics related to Trypanosoma species, addressing implications for parasitic diseases. Further interests encompass synthesis and biological evaluation, research on leishmaniasis, bioactive compounds, antitumor agents, and the synthesis and biological activity of chemical compounds.

Notable recent publications demonstrate the applied and collaborative nature of their work. These include:

  • Synthesis of quinone imine and sulphur-containing compounds with antitumor and trypanocidal activities: redox and biological implications (2020), published in RSC Medicinal Chemistry
  • Starvation and pH stress conditions induced mitochondrial dysfunction, ROS production and autophagy in Trypanosoma cruzi epimastigotes (2020), published in Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  • Antiparasitic and anti-inflammatory activities of ß-lapachone-derived naphthoimidazoles in experimental acute Trypanosoma cruzi infection (2020), published in Memórias do Instituto Oswaldo Cruz
  • Benznidazole and amiodarone combined treatment attenuates cytoskeletal damage in Trypanosoma cruzi-infected cardiac cells (2022), published in Frontiers in Cellular and Infection Microbiology
  • Synthesis, Antitrypanosomal and Antimycobacterial Activities of Coumarin N-acylhydrazonic Derivatives (2020), published in Medicinal Chemistry

Their collaborative network includes frequent co-authors such as Juliana M. C. Barbosa, Renata G. Almeida, Wagner O. Valença, Luísa G. Rosa, and Carlos A. de Simone.

Common publication venues for Solange L. de Castro highlight a strong presence in The Cambridge Structural Database alongside contributions to specialized journals including RSC Medicinal Chemistry, Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, Memórias do Instituto Oswaldo Cruz, and Frontiers in Cellular and Infection Microbiology.

Best Publications

  • Propolis: recent advances in chemistry and plant origin

    Vassya S. Bankova;Solange L. de Castro;Maria C. Marcucci

  • A critical review on Chagas disease chemotherapy.

    José Rodrigues Coura;Solange L de Castro

  • In vitro and in vivo experimental models for drug screening and development for Chagas disease

    Alvaro José Romanha;Solange Lisboa de Castro;Maria de Nazaré Correia Soeiro;Joseli Lannes-Vieira

  • The trypanocidal activity of naphthoquinones: a review.

    Antônio Ventura Pinto;Solange Lisboa de Castro

  • Autophagy in protists

    Michael Duszenko;Michael L Ginger;Ana Brennand;Melisa Gualdrón-López

  • Different cell death pathways induced by drugs in Trypanosoma cruzi: an ultrastructural study.

    Rubem F.S. Menna-Barreto;Kelly Salomão;Andréia P. Dantas;Ricardo M. Santa-Rita

  • Flavonoids and trypanocidal activity of Bulgarian propolis.

    Eliane Prytzyk;Andreia P Dantas;Kelly Salomão;Alberto S Pereira

  • Propolis: Biological and Pharmacological Activities. Therapeutic Uses of This Bee-product

    Solange L Castro

  • The challenge of Chagas' disease chemotherapy: an update of drugs assayed against Trypanosoma cruzi.

    Solange L. de Castro

  • Trypanosoma cruzi targets for new chemotherapeutic approaches

    Maria Nazaré C Soeiro;Solange L de Castro

  • Naphthoquinoidal [1,2,3]-triazole, a new structural moiety active against Trypanosoma cruzi.

    Eufrânio N. da Silva;Rubem F.S. Menna-Barreto;Maria do Carmo F.R. Pinto;Raphael S.F. Silva

  • Brazilian Propolis: Correlation between Chemical Composition and Antimicrobial Activity

    Kelly Salomão;Paulo Roberto S. Pereira;Leila C. Campos;Cintia M. Borba

  • The Double-Edged Sword in Pathogenic Trypanosomatids: The Pivotal Role of Mitochondria in Oxidative Stress and Bioenergetics

    Rubem Figueiredo Sadok Menna-Barreto;Solange Lisboa de Castro

  • Evaluation of the analgesic and anti-inflammatory effects of a Brazilian green propolis.

    Niraldo Paulino;Cristiane Teixeira;Regiane Martins;Amarilis Scremin

  • Effect of a β-lapachone-derived naphthoimidazole on Trypanosoma cruzi: identification of target organelles

    Rubem F. S. Menna-Barreto;Andrea Henriques-Pons;Antônio V. Pinto;José A. Morgado-Diaz

  • Antiparasitic activity of risedronate in a murine model of acute Chagas' disease.

    Luciana R Garzoni;Mariana C Waghabi;Marcos M Baptista;Solange L de Castro

  • Selective in vitro effects of the farnesyl pyrophosphate synthase inhibitor risedronate on Trypanosoma cruzi

    Luciana R. Garzoni;Aura Caldera;Maria de Nazareth L. Meirelles;Solange L.de Castro

  • The effects on Trypanosoma cruzi of novel synthetic naphthoquinones are mediated by mitochondrial dysfunction.

    Rubem F.S. Menna-Barreto;Renata L.S. Goncalves;Elaine M. Costa;Raphael S.F. Silva

  • Synthesis of quinoidal molecules: strategies towards bioactive compounds with an emphasis on lapachones.

    Solange L. de Castro;Flavio da Silva Emery;Eufrânio N. da Silva Júnior

  • Bulgarian propolis induces analgesic and anti-inflammatory effects in mice and inhibits in vitro contraction of airway smooth muscle.

    Niraldo Paulino;Andreia Pires Dantas;Vassya Bankova;Daniela Taggliari Longhi

Frequent Co-Authors

Carlos A.M. Fraga
Carlos A.M. Fraga Federal University of Rio de Janeiro
Vitor F. Ferreira
Vitor F. Ferreira Fluminense Federal University
Nelson Durán
Nelson Durán State University of Campinas
Vassya Bankova
Vassya Bankova Bulgarian Academy of Sciences
Cláudia Pessoa
Cláudia Pessoa Universidade Federal do Ceará
Julio A. Urbina
Julio A. Urbina Instituto Venezolano de Investigaciones Científicas
John F. Bower
John F. Bower University of Liverpool
Isabelle Coppens
Isabelle Coppens Johns Hopkins University
Boris Turk
Boris Turk Jožef Stefan Institute
Egler Chiari
Egler Chiari Universidade Federal de Minas Gerais

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