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Chemistry
Uruguay
2025

D-Index & Metrics

Chemistry

D-Index
61
Citations
10619
World Ranking
9452
National Ranking
3

Research.com Recognitions

  • 2025 - Research.com Chemistry in Uruguay Leader Award

Overview

Hugo Cerecetto is affiliated with the University of the Republic in Uruguay and has a research portfolio spanning the fields of Medicine and Materials Science. Their work integrates several subfields including Materials Chemistry, Radiology, Nuclear Medicine and Imaging, Organic Chemistry, and Molecular Biology. The scientist's publication record reflects a focus on interdisciplinary topics intersecting chemistry, biology, and medical applications.

The prominent themes in their research include:

  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Radiopharmaceutical Chemistry and Applications
  • Boron Compounds in Chemistry
  • Trypanosoma species research and implications
  • Research on Leishmaniasis Studies
  • Advanced biosensing and bioanalysis techniques

Their recent publications demonstrate a particular interest in boron-containing compounds and their biomedical applications, as seen in studies combining cancer therapy with chemical innovation. Notable papers include:

  • "The Rise of Boron-Containing Compounds: Advancements in Synthesis, Medicinal Chemistry, and Emerging Pharmacology" (2024, Chemical Reviews)
  • "Bimodal Therapeutic Agents Against Glioblastoma, One of the Most Lethal Forms of Cancer" (2020, Chemistry - A European Journal)
  • "Closo-Carboranyl- and Metallacarboranyl [1,2,3]triazolyl-Decorated Lapatinib-Scaffold for Cancer Therapy Combining Tyrosine Kinase Inhibition and Boron Neutron Capture Therapy" (2020, Cells)
  • "Sunitinib-Containing Carborane Pharmacophore with the Ability to Inhibit Tyrosine Kinases Receptors FLT3, KIT and PDGFR-β, Exhibits Powerful In Vivo Anti-Glioblastoma Activity" (2020, Cancers)
  • "Sgc8-c Aptamer as a Potential Theranostic Agent for Hemato-Oncological Malignancies" (2020, Cancer Biotherapy and Radiopharmaceuticals)

The venues where Hugo Cerecetto has published frequently include:

  • The Cambridge Structural Database
  • Pharmaceuticals
  • Chemical Reviews
  • Cancers
  • Cancer Biotherapy and Radiopharmaceuticals

The scientist collaborates regularly with several coauthors, notable among them are:

  • Angel H. Romero
  • Marcos Couto
  • Lourdes Gotopo
  • Gustavo Cabrera
  • Pablo Cabral

Hugo Cerecetto's body of work reflects consistent engagement with medicinal chemistry approaches aimed at therapeutic development, particularly focusing on cancer and infectious diseases. Their research often integrates chemical synthesis with biological evaluation, emphasizing radiopharmaceutical applications and novel compound design.

Best Publications

  • Synthetic chalcones, flavanones, and flavones as antitumoral agents: biological evaluation and structure-activity relationships.

    Mauricio Cabrera;Macarena Simoens;Gabriela Falchi;M. Laura Lavaggi

  • Pharmacological properties of indazole derivatives: recent developments.

    Hugo Cerecetto;Alejandra Gerpe;Mercedes González;Vicente J Arán

  • Novel antitrypanosomal agents based on palladium nitrofurylthiosemicarbazone complexes: DNA and redox metabolism as potential therapeutic targets.

    Lucía Otero;Marisol Vieites;Lucía Boiani;Ana Denicola

  • Pharmacological Properties of Furoxans and Benzofuroxans: Recent Developments

    Hugo Cerecetto;Williams Porcal

  • 1,2,5-Oxadiazole N-oxide derivatives and related compounds as potential antitrypanosomal drugs: structure-activity relationships.

    H. Cerecetto;R. Di Maio;M. Gonzalez;M. Risso

  • Vanadium(V) complexes with salicylaldehyde semicarbazone derivatives bearing in vitro anti-tumor activity toward kidney tumor cells (TK-10): crystal structure of [VVO2(5-bromosalicylaldehyde semicarbazone)].

    Pabla Noblı́a;Marisol Vieites;Beatriz S. Parajón-Costa;Enrique J. Baran

  • Mode of action of Nifurtimox and N-oxide-containing heterocycles against Trypanosoma cruzi: Is oxidative stress involved?

    Mariana Boiani;Lucia Piacenza;Paola Hernández;Lucia Boiani

  • In vitro activity and mechanism of action against the protozoan parasite Trypanosoma cruzi of 5-nitrofuryl containing thiosemicarbazones.

    Gabriela Aguirre;Lucı́a Boiani;Hugo Cerecetto;Marcelo Fernández

  • Chemotherapy of Chagas' disease: status and new developments.

    Hugo Cerecetto;Mercedes Gonzalez

  • Synthesis and antitrypanosomal evaluation of E-isomers of 5-nitro-2-furaldehyde and 5-nitrothiophene-2-carboxaldehyde semicarbazone derivatives. structure-activity relationships.

    H. Cerecetto;R. Di Maio;M. Gonzalez;M. Risso

  • Synthesis, trypanocidal activity and docking studies of novel quinoxaline-N-acylhydrazones, designed as cruzain inhibitors candidates.

    Nelilma C. Romeiro;Gabriela Aguirre;Paola Hernández;Mercedes González

  • Quinoxaline N,N′-dioxide derivatives and related compounds as growth inhibitors of Trypanosoma cruzi. Structure–activity relationships

    Gabriela Aguirre;Hugo Cerecetto;Rossanna Di Maio;Mercedes González

  • Indazole N-oxide derivatives as antiprotozoal agents: synthesis, biological evaluation and mechanism of action studies

    Alejandra Gerpe;Gabriela Aguirre;Lucía Boiani;Hugo Cerecetto

  • Novel Antiprotozoal Products: Imidazole and Benzimidazole N‐Oxide Derivatives and Related Compounds

    Gabriela Aguirre;Mariana Boiani;Hugo Cerecetto;Alejandra Gerpe

  • New Vanadium(V) Complexes with Salicylaldehyde Semicarbazone Derivatives: Synthesis, Characterization, and in vitro Insulin-Mimetic Activity − Crystal Structure of [VvO2(salicylaldehyde semicarbazone)]

    Pabla Noblía;Enrique J. Baran;Lucía Otero;Patricia Draper

  • Synthesis, isomer characterization, and anti-inflammatory properties of nitroarachidonate.

    Andrés Trostchansky;José M. Souza;Ana Ferreira;Mariana Ferrari

  • Imidazolidines as new anti-Trypanosoma cruzi agents: biological evaluation and structure-activity relationships.

    M. Cristina Caterina;Isabel A. Perillo;Lucía Boiani;Horacio Pezaroglo

  • Improving anti-trypanosomal activity of 3-aminoquinoxaline-2-carbonitrile N1,N4-dioxide derivatives by complexation with vanadium

    Carolina Urquiola;Marisol Vieites;Gabriela Aguirre;Adoración Marín

  • Platinum(II) metal complexes as potential anti-Trypanosoma cruzi agents.

    Marisol Vieites;Lucía Otero;Diego Santos;Jeannette Toloza

  • Synthesis and anti-trypanosomal activity of novel 5-nitro-2-furaldehyde and 5-nitrothiophene-2-carboxaldehyde semicarbazone derivatives

    Hugo Cerecetto;Rossanna Di Maio;Gerardo Ibarruri;Gustavo Seoane

Frequent Co-Authors

Mercedes González
Mercedes González University of the Republic
Oscar E. Piro
Oscar E. Piro National University of La Plata
Ana Denicola
Ana Denicola University of the Republic
Eduardo E. Castellano
Eduardo E. Castellano Universidade de São Paulo
Clara Viñas
Clara Viñas Institut de Ciència de Materials de Barcelona
Francesc Teixidor
Francesc Teixidor Institut de Ciència de Materials de Barcelona
Eliezer J. Barreiro
Eliezer J. Barreiro Federal University of Rio de Janeiro
Isabel Correia
Isabel Correia Instituto Superior Técnico
João Costa Pessoa
João Costa Pessoa Instituto Superior Técnico
Marta Cascante
Marta Cascante University of Barcelona

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