World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
57
Citations
15066
World Ranking
10948
National Ranking
73

Overview

Eliezer J. Barreiro is affiliated with the Federal University of Rio de Janeiro in Brazil and has contributed extensively to research in medicine, biochemistry, genetics, molecular biology, and chemistry. Their work spans across several specific subfields, including organic chemistry, molecular biology, physiology, oncology, and pharmacology.

Their research topics include:

  • Synthesis and biological activity
  • Adenosine and purinergic signaling
  • Computational drug discovery methods
  • Peptidase inhibition and analysis
  • Research on leishmaniasis studies
  • Synthesis and biological evaluation
  • Nitric oxide and endothelin effects

Frequent co-authors who have collaborated with Barreiro on multiple occasions include Lídia Moreira Lima, Tadeu L. Montagnoli, Gisele Zapata-Sudo, Lucas Silva Franco, and Gisele Barbosa.

The scientist has published regularly in venues such as Circulation Research, Pharmaceuticals, Molecules, ACS Omega, and the Journal of the Brazilian Chemical Society.

Recent published papers by Barreiro include:

  • β-lactam antibiotics: An overview from a medicinal chemistry perspective, 2020, European Journal of Medicinal Chemistry
  • Identification of LASSBio-1945 as an inhibitor of SARS-CoV-2 main protease (MPRO) through in silico screening supported by molecular docking and a fragment-based pharmacophore model, 2020, RSC Medicinal Chemistry
  • Bioisosteric Replacement of Arylamide-Linked Spine Residues with N-Acylhydrazones and Selenophenes as a Design Strategy to Novel Dibenzosuberone Derivatives as Type I 1/2 p38α MAP Kinase Inhibitors, 2020, Journal of Medicinal Chemistry
  • Comparative chemical and biological hydrolytic stability of homologous esters and isosteres, 2022, Journal of Enzyme Inhibition and Medicinal Chemistry
  • Revisiting Nitroaromatic Drugs: Mechanisms of Bioactivation, Metabolism and Toxicity and Methods to Synthesize Nitroaromatic Fragments, 2024, Journal of the Brazilian Chemical Society

Best Publications

  • Molecular hybridization: A useful tool in the design of new drug prototypes

    Claudio Viegas-Junior;Amanda Danuello;Vanderlan da Silva Bolzani;Eliezer J. Barreiro

  • The methylation effect in medicinal chemistry.

    Eliezer J. Barreiro;Arthur E. Kümmerle;Carlos A. M. Fraga

  • Bioisosterism: a useful strategy for molecular modification and drug design.

    Lídia Moreira Lima;Eliezer J Barreiro

  • From nature to drug discovery: the indole scaffold as a 'privileged structure'.

    Fernando Rodrigues de Sa Alves;Eliezer J. Barreiro;Carlos Alberto Manssour Fraga

  • β-lactam antibiotics: An overview from a medicinal chemistry perspective.

    Lidia Moreira Lima;Bianca Nascimento Monteiro da Silva;Gisele Barbosa;Eliezer J. Barreiro

  • Ru(II) Compounds: Next-Generation Anticancer Metallotherapeutics?

    Sreekanth Thota;Daniel Alencar Rodrigues;Debbie C. Crans;Eliezer J. Barreiro

  • Privileged structures: a useful concept for the rational design of new lead drug candidates.

    Carolina D. Duarte;Eliezer J. Barreiro;Carlos A.M. Fraga

  • Synthesis and evaluation of analgesic, antiinflammatory and antiplatelet properties of new 2-pyridylarylhydrazone derivatives

    Adriane R. Todeschini;Ana Luisa P. de Miranda;Kelly Christine M. da Silva;Sergio C. Parrini

  • Synthesis and analgesic activity of novel N-acylarylhydrazones and isosters, derived from natural safrole.

    P. C. Lima;L. M. Lima;K. C. M. Da Silva;P. H. O. Leda

  • Synthesis and anti-inflammatory activity of phthalimide derivatives, designed as new thalidomide analogues.

    Lı́dia M Lima;Paulo Castro;Alexandre L Machado;Carlos Alberto M Fraga

  • Antiplatelet properties of novel N-substituted-phenyl-1,2,3-triazole-4-acylhydrazone derivatives.

    Anna C. Cunha;Juliana M. Figueiredo;Jorge L.M. Tributino;Ana L.P. Miranda

  • Discovery of novel analgesic and anti-inflammatory 3-arylamine-imidazo[1,2-a]pyridine symbiotic prototypes.

    Renata B. Lacerda;Cleverton K.F. de Lima;Leandro L. da Silva;Nelilma C. Romeiro

  • N-Acylhydrazones as drugs.

    Sreekanth Thota;Sreekanth Thota;Daniel A. Rodrigues;Pedro de Sena Murteira Pinheiro;Lídia M. Lima

  • New class of potent antinociceptive and antiplatelet 10H-phenothiazine-1-acylhydrazone derivatives

    Gildásio A. Silva;Luciana M.M. Costa;Fernanda C.F. Brito;Ana L.P. Miranda

  • Produtos naturais como candidatos a fármacos úteis no tratamento do Mal de Alzheimer

    Cláudio Viegas Junior;Vanderlan da Silva Bolzani;Maysa Furlan;Carlos Alberto Manssour Fraga

  • Design, synthesis, and pharmacological evaluation of N-acylhydrazones and novel conformationally constrained compounds as selective and potent orally active phosphodiesterase-4 inhibitors.

    Arthur E Kümmerle;Martine Schmitt;Suzana V S Cardozo;Suzana V S Cardozo;Claire Lugnier

  • Novel 2-chloro-4-anilino-quinazoline derivatives as EGFR and VEGFR-2 dual inhibitors.

    Maria Letícia de Castro Barbosa;Lídia Moreira Lima;Roberta Tesch;Carlos Mauricio R. Sant'Anna

  • Further bioactive piperidine alkaloids from the flowers and green fruits of Cassia spectabilis.

    Claudio Viegas;Vanderlan Da S. Bolzani;Maysa Furlan;Eliezer J. Barreiro

  • Synthesis and vasodilatory activity of new N-acylhydrazone derivatives, designed as LASSBio-294 analogues

    Alexandre G. Silva;Gisele Zapata-Sudo;Arthur E. Kummerle;Carlos A.M. Fraga

  • Synthesis, trypanocidal activity and docking studies of novel quinoxaline-N-acylhydrazones, designed as cruzain inhibitors candidates.

    Nelilma C. Romeiro;Gabriela Aguirre;Paola Hernández;Mercedes González

Frequent Co-Authors

Carlos A.M. Fraga
Carlos A.M. Fraga Federal University of Rio de Janeiro
Vanderlan da Silva Bolzani
Vanderlan da Silva Bolzani Sao Paulo State University
Andrew E. Greene
Andrew E. Greene Joseph Fourier University
Mercedes González
Mercedes González University of the Republic
Stefan Laufer
Stefan Laufer University of Tübingen
Hugo Cerecetto
Hugo Cerecetto University of the Republic
Cláudia Pessoa
Cláudia Pessoa Universidade Federal do Ceará
Russolina B. Zingali
Russolina B. Zingali Federal University of Rio de Janeiro
Edson X. Albuquerque
Edson X. Albuquerque University of Maryland, Baltimore
Vitor F. Ferreira
Vitor F. Ferreira Fluminense Federal University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying chemistry in the USA opens up a range of career opportunities, many of which can be pursued through specialized online degrees. For those interested in legal aspects related to chemistry, exploring a paralegal studies associate degree can provide a solid foundation in understanding regulatory and compliance issues in chemical industries.

In the pharmaceutical sector, chemistry graduates often pursue careers as sales representatives or pharmacists. Understanding how much do pharmaceutical reps make helps set realistic expectations for those considering this career path. Moreover, detailed guidance on how do you become a pharmacist is valuable for students aiming to enter this essential healthcare profession.

For those fascinated by the forensic or medical side of chemistry, becoming an autopsy technician is another viable option. Resources on autopsy technician careers outline necessary education and job outlook, linking closely to skills gained in chemistry programs.

By aligning your chemistry studies with these related online degrees and career pathways, you can tailor your education to meet diverse industry needs and boost your career prospects in both science and applied fields.

Best Scientists Citing Eliezer J. Barreiro

Trending Scientists

Recently Published Articles