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Genetics

D-Index
66
Citations
14664
World Ranking
2625
National Ranking
1161

Overview

Tim Schedl is affiliated with Washington University in St. Louis in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with a significant emphasis on molecular biology, aging, genetics, cell biology, and endocrine and autonomic systems.

The scientist has contributed extensively to the study of genetics, aging, and longevity in model organisms. Other notable topics of research include mitochondrial function and pathology, CRISPR and genetic engineering, pluripotent stem cells research, circadian rhythm and melatonin, genetics and neurodevelopmental disorders, and bioinformatics and genomic networks.

Schedl's recent papers encompass a range of subjects and were published in recognized scientific venues:

  • WormBase in 2022-data, processes, and tools for analyzing Caenorhabditis elegans, 2022, Genetics
  • WormBase 2024: status and transitioning to Alliance infrastructure, 2024, Genetics
  • Characterization of Metabolic Patterns in Mouse Oocytes during Meiotic Maturation, 2020, Molecular Cell
  • Model organisms contribute to diagnosis and discovery in the undiagnosed diseases network: current state and a future vision, 2021, Orphanet Journal of Rare Diseases
  • GLP-1 Notch-LAG-1 CSL control of the germline stem cell fate is mediated by transcriptional targets lst-1 and sygl-1, 2020, PLoS Genetics

Frequently publishing in venues such as bioRxiv (Cold Spring Harbor Laboratory), PubMed, Genetics, PLoS Genetics, and Proceedings of the National Academy of Sciences, Schedl has established a presence in leading scientific journals relevant to genetics and molecular biology.

  • bioRxiv (Cold Spring Harbor Laboratory)
  • PubMed
  • Genetics
  • PLoS Genetics
  • Proceedings of the National Academy of Sciences

Schedl has collaborated frequently with several researchers, including:

  • Stephen C. Pak
  • Gary A. Silverman
  • Dustin Baldridge
  • Ariz Mohammad
  • Lindsay C. Burrage

Best Publications

  • CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration.

    Tina L. Gumienny;Tina L. Gumienny;Enrico Brugnera;Annie-Carole Tosello-Trampont;Jason M. Kinchen;Jason M. Kinchen

  • Whole-genome sequencing and variant discovery in C. elegans.

    La Deana W. Hillier;Gabor T. Marth;Aaron R. Quinlan;David Dooling

  • On the control of oocyte meiotic maturation and ovulation in Caenorhabditis elegans

    James McCarter;Bart Bartlett;Thanh Dang;Tim Schedl

  • A Sperm Cytoskeletal Protein That Signals Oocyte Meiotic Maturation and Ovulation

    Michael A. Miller;Viet Q. Nguyen;Min-Ho Lee;Mary Kosinski

  • Gld-1, a Tumor Suppressor Gene Required for Oocyte Development in Caenorhabditis Elegans

    R Francis;M K Barton;J Kimble;T Schedl

  • fog-2, a germ-line-specific sex determination gene required for hermaphrodite spermatogenesis in Caenorhabditis elegans.

    Tim Schedl;Judith Kimble

  • High Fat Diet Induced Developmental Defects in the Mouse: Oocyte Meiotic Aneuploidy and Fetal Growth Retardation/Brain Defects

    Kerri M. Luzzo;Qiang Wang;Scott H. Purcell;Maggie Chi

  • WormBase 2016: expanding to enable helminth genomic research

    Kevin L. Howe;Bruce J. Bolt;Scott Cain;Juancarlos Chan

  • Germ-line tumor formation caused by activation of glp-1, a Caenorhabditis elegans member of the Notch family of receptors

    Laura Wilson Berry;Bethany Westlund;Tim Schedl

  • GLD-1, a Cytoplasmic Protein Essential for Oocyte Differentiation, Shows Stage- and Sex-Specific Expression during Caenorhabditis elegans Germline Development

    Allan R. Jones;Ross Francis;Tim Schedl

  • Mutations in gld-1, a female germ cell-specific tumor suppressor gene in Caenorhabditis elegans, affect a conserved domain also found in Src-associated protein Sam68.

    Allan R. Jones;Tim Schedl

  • Gain-of-Function Mutations of fem-3, a Sex-Determination Gene in Caenorhabditis elegans

    M. Kathryn Barton;Timothy B. Schedl;Judith Kimble

  • WormBase: a modern Model Organism Information Resource.

    Todd W. Harris;Valerio Arnaboldi;Scott Cain;Juancarlos Chan

  • Soma-Germ Cell Interactions in Caenorhabditis elegans: Multiple Events of Hermaphrodite Germline Development Require the Somatic Sheath and Spermathecal Lineages

    James McCarter;Bart Bartlett;Thanh Dang;Tim Schedl

  • Translational Repression of C. elegans p53 by GLD-1 Regulates DNA Damage-Induced Apoptosis

    Björn Schumacher;Momoyo Hanazawa;Min-Ho Lee;Sudhir Nayak

  • Maternal Diabetes Causes Mitochondrial Dysfunction and Meiotic Defects in Murine Oocytes

    Qiang Wang;Ann M. Ratchford;Maggie M.-Y. Chi;Erica Schoeller

  • A High-Resolution C. elegans Essential Gene Network Based on Phenotypic Profiling of a Complex Tissue

    Rebecca A. Green;Huey Ling Kao;Anjon Audhya;Swathi Arur

  • Analysis of the multiple roles of gld-1 in germline development: Interactions with the sex determination cascade and the glp-1 signaling pathway

    Ross Francis;Eleanor M Maine;Tim Schedl

  • Developmental Genetics of the Germ Line

    Tim Schedl

  • RNA-binding proteins.

    Min Ho Lee;Tim Schedl

Frequent Co-Authors

Kelle H. Moley
Kelle H. Moley Washington University in St. Louis
Paul W. Sternberg
Paul W. Sternberg California Institute of Technology
William F. Dove
William F. Dove University of Wisconsin–Madison
Michael F. Wangler
Michael F. Wangler Baylor College of Medicine
Aaron R. Quinlan
Aaron R. Quinlan University of Utah
Monte Westerfield
Monte Westerfield University of Oregon
Gabor T. Marth
Gabor T. Marth University of Utah
Lilianna Solnica-Krezel
Lilianna Solnica-Krezel Washington University in St. Louis
John A. Phillips
John A. Phillips Vanderbilt University Medical Center
Jill A. Rosenfeld
Jill A. Rosenfeld Baylor College of Medicine

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