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D-Index & Metrics

Molecular Biology

D-Index
75
Citations
18357
World Ranking
1200
National Ranking
621

Overview

Karen Oegema is affiliated with the University of California, San Diego in the United States and has a research focus within the broader field of Biochemistry, Genetics and Molecular Biology. Their scholarly output covers several specialized subfields, including Molecular Biology, Cell Biology, Aging, Plant Science, and Genetics.

The scientist's research emphasizes several key topics: Microtubule and mitosis dynamics, Cellular transport and secretion, DNA Repair Mechanisms, Genetics, Aging, and Longevity in Model Organisms, Photosynthetic Processes and Mechanisms, Chromosomal and Genetic Variations, and Ubiquitin and proteasome pathways.

Oegema has contributed to multiple research publications, with notable recent papers including:

  • TRIM37 controls cancer-specific vulnerability to PLK4 inhibition, 2020, Nature
  • Polo-like kinase 1 independently controls microtubule-nucleating capacity and size of the centrosome, 2020, The Journal of Cell Biology
  • A tripartite mechanism catalyzes Mad2-Cdc20 assembly at unattached kinetochores, 2020, Science
  • Control of cell proliferation by memories of mitosis, 2024, Science
  • Centriole-independent mitotic spindle assembly relies on the PCNT-CDK5RAP2 pericentriolar matrix, 2020, The Journal of Cell Biology

Frequent co-authors of Karen Oegema include:

  • Arshad Desai (29 collaborations)
  • Pablo Lara-González (10 collaborations)
  • Midori Ohta (9 collaborations)
  • Kevin D. Corbett (9 collaborations)
  • Franz Meitinger (7 collaborations)

Their publications have appeared in several venues, with the most recurrent being:

  • bioRxiv (Cold Spring Harbor Laboratory) with 11 publications
  • The Journal of Cell Biology with 5 publications
  • Current Biology with 4 publications
  • UNC Libraries with 3 publications
  • Science with 2 publications

Karen Oegema's work addresses complex biological mechanisms related to cell division and molecular structures within cells, including mitosis and microtubule dynamics, with investigations extending into DNA repair and genetic factors linked to aging. Their range also includes studying photosynthetic processes and chromosomal variations, covering diverse aspects of cellular and molecular biology.

Best Publications

  • Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III

    Pierre Gönczy;Pierre Gönczy;Christophe Echeverri;Christophe Echeverri;Karen Oegema;Karen Oegema;Alan Coulson

  • Full-genome RNAi profiling of early embryogenesis in Caenorhabditis elegans

    B. Sönnichsen;L. B. Koski;A. Walsh;P. Marschall

  • Cytokinesis in animal cells

    Rebecca A Green;Ewa Paluch;Karen Oegema

  • Aurora-A kinase is required for centrosome maturation in Caenorhabditis elegans

    Eva Hannak;Matthew Kirkham;Anthony A. Hyman;Karen Oegema

  • Functional analysis of kinetochore assembly in Caenorhabditis elegans.

    Karen Oegema;Arshad Desai;Sonja Rybina;Matthew Kirkham

  • A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension

    Iain M. Cheeseman;Sherry Niessen;Scott Anderson;Francie Hyndman

  • Reversible centriole depletion with an inhibitor of Polo-like kinase 4

    Yao Liang Wong;John V. Anzola;Robert L. Davis;Michelle Yoon

  • Characterization of Two Related Drosophila γ-tubulin Complexes that Differ in Their Ability to Nucleate Microtubules

    Karen Oegema;Christiane Wiese;Ona C. Martin;Ronald A. Milligan

  • SAS-4 Is a C. elegans Centriolar Protein that Controls Centrosome Size

    Matthew Kirkham;Thomas Müller-Reichert;Karen Oegema;Stephan Grill

  • Functional Analysis of a Human Homologue of the Drosophila Actin Binding Protein Anillin Suggests a Role in Cytokinesis

    Karen Oegema;Matthew S. Savoian;Timothy J. Mitchison;Christine M. Field

  • A complex containing the Sm protein CAR-1 and the RNA helicase CGH-1 is required for embryonic cytokinesis in Caenorhabditis elegans

    Anjon Audhya;Francie Hyndman;Ian X. McLeod;Amy S. Maddox

  • Katanin controls mitotic and meiotic spindle length

    Karen McNally;Anjon Audhya;Karen Oegema;Francis J. McNally

  • Centriole assembly requires both centriolar and pericentriolar material proteins.

    Alexander Dammermann;Thomas Müller-Reichert;Laurence Pelletier;Bianca Habermann

  • Cytokinesis in eukaryotes: a mechanistic comparison.

    Christine Field;Rong Li;Karen Oegema

  • KNL-1 directs assembly of the microtubule-binding interface of the kinetochore in C. elegans

    Arshad Desai;Sonja Rybina;Thomas Müller-Reichert;Andrej Shevchenko

  • Recruitment of the gamma-tubulin ring complex to Drosophila salt-stripped centrosome scaffolds.

    Michelle Moritz;Yixian Zheng;Bruce M. Alberts;Karen Oegema

  • Functional genomics identifies a Myb domain–containing protein family required for assembly of CENP-A chromatin

    Paul S. Maddox;Francie Hyndman;Joost Monen;Karen Oegema

  • A High-Resolution C. elegans Essential Gene Network Based on Phenotypic Profiling of a Complex Tissue

    Rebecca A. Green;Huey Ling Kao;Anjon Audhya;Swathi Arur

  • Structural Memory in the Contractile Ring Makes the Duration of Cytokinesis Independent of Cell Size

    Ana Carvalho;Arshad Desai;Karen Oegema

  • Full-genome RNAi profiling of early embryogenesis in Caenorhabditis

    M. Hewitson;S. Lazik;C. Martin;J. Stamford

Frequent Co-Authors

Arshad Desai
Arshad Desai University of California, San Diego
Anthony A. Hyman
Anthony A. Hyman Max Planck Institute of Molecular Cell Biology and Genetics
John R. Yates
John R. Yates Scripps Research Institute
Anjon Audhya
Anjon Audhya University of Wisconsin–Madison
Steven J.M. Jones
Steven J.M. Jones University of British Columbia
Timothy J. Mitchison
Timothy J. Mitchison Harvard University
Yixian Zheng
Yixian Zheng Carnegie Institution for Science
Pierre Gönczy
Pierre Gönczy École Polytechnique Fédérale de Lausanne
Jordan W. Raff
Jordan W. Raff University of Oxford

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