World's Best Scientists 2026 revealed!
Iain M. Cheeseman

Iain M. Cheeseman

D-Index & Metrics

Biology and Biochemistry

D-Index
62
Citations
18223
World Ranking
10604
National Ranking
4606

Overview

Iain M. Cheeseman is affiliated with the Massachusetts Institute of Technology (MIT) in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with a notable emphasis on molecular biology and cell biology. Their scholarly work spans several subfields, including plant science, public health, environmental and occupational health, and biophysics.

The scientist has contributed extensively to research on microtubule and mitosis dynamics, genomics and chromatin dynamics, chromosomal and genetic variations, RNA and protein synthesis mechanisms, RNA research and splicing, cellular transport and secretion, and ubiquitin and proteasome pathways.

Frequent collaborators in their research include Jimmy Ly, Kuan-Chung Su, Brittania Moodie, Gunter B. Sissoko, and Ekaterina V. Tarasovetc. These partnerships have supported a sustained research presence in prominent scientific venues.

Their publications often appear in journals such as bioRxiv (Cold Spring Harbor Laboratory), Molecular Biology of the Cell, Current Biology, Developmental Cell, and Cell.

Selected recent papers demonstrate the range and focus of their research:

  • Cellular Mechanisms and Regulation of Quiescence, 2020, Developmental Cell
  • The phenotypic landscape of essential human genes, 2022, Cell
  • Alpha-satellite RNA transcripts are repressed by centromere-nucleolus associations, 2020, eLife
  • Kinetochore assembly throughout the cell cycle, 2021, Seminars in Cell and Developmental Biology
  • Cohesin Removal Reprograms Gene Expression upon Mitotic Entry, 2020, Molecular Cell

Best Publications

  • The Conserved KMN Network Constitutes the Core Microtubule-Binding Site of the Kinetochore

    Iain M. Cheeseman;Joshua S. Chappie;Elizabeth M. Wilson-Kubalek;Arshad Desai

  • Molecular architecture of the kinetochore–microtubule interface

    Iain M. Cheeseman;Arshad Desai

  • Phospho-regulation of kinetochore-microtubule attachments by the Aurora kinase Ipl1p.

    Iain M. Cheeseman;Scott Anderson;Miri Jwa;Erin M. Green

  • The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres.

    Masahiro Okada;Iain M. Cheeseman;Tetsuya Hori;Katsuya Okawa

  • The molecular basis for centromere identity and function

    Kara L. McKinley;Iain M. Cheeseman

  • Aurora B phosphorylates spatially distinct targets to differentially regulate the kinetochore-microtubule interface

    Julie P.I. Welburn;Mathijs Vleugel;Dan Liu;John R. Yates

  • A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension

    Iain M. Cheeseman;Sherry Niessen;Scott Anderson;Francie Hyndman

  • CCAN makes multiple contacts with centromeric DNA to provide distinct pathways to the outer kinetochore.

    Tetsuya Hori;Miho Amano;Aussie Suzuki;Chelsea B. Backer

  • Sensing centromere tension: Aurora B and the regulation of kinetochore function

    Michael A. Lampson;Iain M. Cheeseman

  • Regulated targeting of protein phosphatase 1 to the outer kinetochore by KNL1 opposes Aurora B kinase

    Dan Liu;Mathijs Vleugel;Chelsea B. Backer;Tetsuya Hori

  • Induced Ectopic Kinetochore Assembly Bypasses the Requirement for CENP-A Nucleosomes

    Karen E. Gascoigne;Kozo Takeuchi;Aussie Suzuki;Tetsuya Hori

  • Chromosome- and spindle-pole-derived signals generate an intrinsic code for spindle position and orientation

    Tomomi Kiyomitsu;Iain M. Cheeseman

  • Functional genomics, proteomics, and regulatory DNA analysis in isogenic settings using zinc finger nuclease-driven transgenesis into a safe harbor locus in the human genome

    Russell C. DeKelver;Vivian M. Choi;Erica A. Moehle;David E. Paschon

  • CENP-T-W-S-X Forms a Unique Centromeric Chromatin Structure with a Histone-like Fold.

    Tatsuya Nishino;Kozo Takeuchi;Karen E. Gascoigne;Aussie Suzuki

  • The human kinetochore Ska1 complex facilitates microtubule depolymerization-coupled motility.

    Julie P.I. Welburn;Ekaterina L. Grishchuk;Chelsea B. Backer;Elizabeth M. Wilson-Kubalek

  • A combined approach for the localization and tandem affinity purification of protein complexes from metazoans.

    Iain M. Cheeseman;Arshad Desai

  • A cluster of five cell wall-associated receptor kinase genes, Wak1–5, are expressed in specific organs of Arabidopsis

    Zheng-Hui He;Iain Cheeseman;Deze He;Bruce D. Kohorn

  • Architecture of the budding yeast kinetochore reveals a conserved molecular core

    Stefan Westermann;Iain M. Cheeseman;Scott Anderson;John R. Yates

  • Cortical Dynein and Asymmetric Membrane Elongation Coordinately Position the Spindle in Anaphase

    Tomomi Kiyomitsu;Iain McPherson Cheeseman

  • The human Mis12 complex is required for kinetochore assembly and proper chromosome segregation

    Susan L. Kline;Iain M. Cheeseman;Tetsuya Hori;Tatsuo Fukagawa

Frequent Co-Authors

Arshad Desai
Arshad Desai University of California, San Diego
Tatsuo Fukagawa
Tatsuo Fukagawa Osaka University
John R. Yates
John R. Yates Scripps Research Institute
David G. Drubin
David G. Drubin University of California, Berkeley
Helder Maiato
Helder Maiato University of Porto
Michael A. Lampson
Michael A. Lampson University of Pennsylvania
Karen Oegema
Karen Oegema University of California, San Diego
Ronald A. Milligan
Ronald A. Milligan Scripps Research Institute
Ben E. Black
Ben E. Black University of Pennsylvania
Robert H. Singer
Robert H. Singer Albert Einstein College of Medicine

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