Iain M. Cheeseman mainly focuses on Cell biology, Kinetochore, Ndc80 complex, NDC80 and Kinetochore assembly. Iain M. Cheeseman is interested in Microtubule, which is a branch of Cell biology. His research on Kinetochore often connects related topics like Centromere.
His research investigates the link between Ndc80 complex and topics such as Kinetochore microtubule that cross with problems in Astral microtubules, DSN1 and Chromosome passenger complex. His Aurora Kinase B study which covers Biorientation that intersects with Aurora inhibitor. His work carried out in the field of Spindle apparatus brings together such families of science as Mitosis, Chromosome segregation and Cell Cycle Protein.
His main research concerns Cell biology, Kinetochore, Microtubule, Spindle apparatus and Mitosis. His studies deal with areas such as Cell division, Aurora B kinase, Centromere, Anaphase and Spindle pole body as well as Cell biology. His research combines Chromosome segregation and Kinetochore.
His Microtubule study incorporates themes from Chromosome movement, Microtubule nucleation and Kinetochore microtubule. Iain M. Cheeseman has included themes like Cyclin-dependent kinase and Polo-like kinase in his Spindle apparatus study. Iain M. Cheeseman has researched Mitosis in several fields, including Cell cycle and Sister chromatids.
His scientific interests lie mostly in Cell biology, Mitosis, Centromere, Kinetochore and Chromosome segregation. His biological study focuses on Organelle. His work deals with themes such as RNA, Nucleolus and Gene expression, which intersect with Centromere.
His Kinetochore research focuses on Kinetochore assembly in particular. His Kinetochore assembly research is multidisciplinary, incorporating perspectives in Xenopus and Ndc80 complex. His studies in Chromosome segregation integrate themes in fields like Spindle checkpoint and Protein kinase domain.
The scientist’s investigation covers issues in Cell biology, Mitosis, Centromere, Chromosome segregation and Gene expression. His study in Cell biology is interdisciplinary in nature, drawing from both Cell cycle and Cell type. His Mitosis research is multidisciplinary, incorporating elements of Cell division and Kinetochore.
His biological study spans a wide range of topics, including Histone and Cellular differentiation. Iain M. Cheeseman interconnects Chromatin, Prophase and RNA polymerase in the investigation of issues within Centromere. His Chromosome segregation study combines topics in areas such as Spindle checkpoint, Cohesin and Protein kinase domain.
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The Conserved KMN Network Constitutes the Core Microtubule-Binding Site of the Kinetochore
Iain M. Cheeseman;Joshua S. Chappie;Elizabeth M. Wilson-Kubalek;Arshad Desai.
Molecular architecture of the kinetochore–microtubule interface
Iain M. Cheeseman;Arshad Desai.
Nature Reviews Molecular Cell Biology (2008)
Phospho-regulation of kinetochore-microtubule attachments by the Aurora kinase Ipl1p.
Iain M. Cheeseman;Scott Anderson;Miri Jwa;Erin M. Green.
The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres.
Masahiro Okada;Iain M. Cheeseman;Tetsuya Hori;Katsuya Okawa.
Nature Cell Biology (2006)
Aurora B phosphorylates spatially distinct targets to differentially regulate the kinetochore-microtubule interface
Julie P.I. Welburn;Mathijs Vleugel;Dan Liu;John R. Yates.
Molecular Cell (2010)
A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension
Iain M. Cheeseman;Sherry Niessen;Scott Anderson;Francie Hyndman.
Genes & Development (2004)
Sensing centromere tension: Aurora B and the regulation of kinetochore function
Michael A. Lampson;Iain M. Cheeseman.
Trends in Cell Biology (2011)
Regulated targeting of protein phosphatase 1 to the outer kinetochore by KNL1 opposes Aurora B kinase
Dan Liu;Mathijs Vleugel;Chelsea B. Backer;Tetsuya Hori.
Journal of Cell Biology (2010)
CCAN makes multiple contacts with centromeric DNA to provide distinct pathways to the outer kinetochore.
Tetsuya Hori;Miho Amano;Aussie Suzuki;Chelsea B. Backer.
Functional genomics, proteomics, and regulatory DNA analysis in isogenic settings using zinc finger nuclease-driven transgenesis into a safe harbor locus in the human genome
Russell C. DeKelver;Vivian M. Choi;Erica A. Moehle;David E. Paschon.
Genome Research (2010)
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