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Helder Maiato

Helder Maiato

University of Porto
Portugal

Research.com Recognitions

Awards & Achievements

Member of the European Molecular Biology Organization (EMBO)

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Mitosis
  • Spindle apparatus

Helder Maiato focuses on Cell biology, Kinetochore, Spindle apparatus, Mitosis and Microtubule. His study in Cell biology is interdisciplinary in nature, drawing from both Centromere, Kinetochore microtubule, Astral microtubules, Spindle checkpoint and Spindle pole body. The study incorporates disciplines such as Aster and Anaphase in addition to Kinetochore.

The Spindle apparatus study combines topics in areas such as Dynein and Chromosome segregation. His research ties Metaphase and Mitosis together. He studied Microtubule and Centrosome that intersect with Golgi apparatus, Microtubule-associated protein and Spindle midzone.

His most cited work include:

  • Stuck in Division or Passing through: What Happens When Cells Cannot Satisfy the Spindle Assembly Checkpoint (532 citations)
  • Essential roles of Drosophila inner centromere protein (INCENP) and aurora B in histone H3 phosphorylation, metaphase chromosome alignment, kinetochore disjunction, and chromosome segregation. (421 citations)
  • Asymmetric CLASP-Dependent Nucleation of Noncentrosomal Microtubules at the trans-Golgi Network (385 citations)

What are the main themes of his work throughout his whole career to date?

Helder Maiato spends much of his time researching Cell biology, Mitosis, Kinetochore, Spindle apparatus and Microtubule. His biological study spans a wide range of topics, including Spindle checkpoint, Aurora B kinase, Mitotic exit, Anaphase and Spindle pole body. His work is dedicated to discovering how Mitosis, Centrosome are connected with Centriole and other disciplines.

His Kinetochore research integrates issues from Metaphase, Centromere and Biophysics. His work in Spindle apparatus tackles topics such as Kinesin which are related to areas like Prometaphase. His studies deal with areas such as Microtubule nucleation, Chromosome instability and Actin cytoskeleton as well as Microtubule.

He most often published in these fields:

  • Cell biology (150.52%)
  • Mitosis (109.90%)
  • Kinetochore (92.19%)

What were the highlights of his more recent work (between 2018-2021)?

  • Cell biology (150.52%)
  • Mitosis (109.90%)
  • Microtubule (73.44%)

In recent papers he was focusing on the following fields of study:

His scientific interests lie mostly in Cell biology, Mitosis, Microtubule, Kinetochore and Spindle apparatus. His Cell biology research is multidisciplinary, incorporating perspectives in Spindle checkpoint, Mitotic exit, Anaphase and Centrosome. Helder Maiato has researched Mitosis in several fields, including Metaphase, Chromosome segregation and Myosin.

His Tubulin study in the realm of Microtubule connects with subjects such as Chromothripsis. His research in Kinetochore is mostly focused on Kinetochore microtubule. The various areas that Helder Maiato examines in his Spindle apparatus study include Molecular motor and Cytoskeleton.

Between 2018 and 2021, his most popular works were:

  • Spatiotemporal control of mitotic exit during anaphase by an aurora B-Cdk1 crosstalk (17 citations)
  • Spatiotemporal control of mitotic exit during anaphase by an aurora B-Cdk1 crosstalk (17 citations)
  • Coherent-hybrid STED: high contrast sub-diffraction imaging using a bi-vortex depletion beam. (17 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Mitosis
  • DNA

His primary areas of investigation include Cell biology, Mitosis, Kinetochore, Microtubule and Tubulin. His Cell biology study combines topics from a wide range of disciplines, such as Spindle apparatus, Spindle midzone, Mitotic exit and Centrosome. His work on KIF15 as part of general Spindle apparatus study is frequently linked to Kinesin 13, therefore connecting diverse disciplines of science.

His work in Mitosis tackles topics such as Spindle checkpoint which are related to areas like Aurora B kinase, Chromosome separation, Anaphase and Chromosome decondensation. His Microtubule research is multidisciplinary, incorporating elements of Flux, Biophysics and Chromosome segregation, Chromosome congression. His work carried out in the field of Tubulin brings together such families of science as Kinetochore microtubule and Chromosome instability.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Stuck in Division or Passing through: What Happens When Cells Cannot Satisfy the Spindle Assembly Checkpoint

Conly L. Rieder;Helder Maiato.
Developmental Cell (2004)

715 Citations

Essential roles of Drosophila inner centromere protein (INCENP) and aurora B in histone H3 phosphorylation, metaphase chromosome alignment, kinetochore disjunction, and chromosome segregation.

Richard R. Adams;Helder Maiato;William C. Earnshaw;Mar Carmena.
Journal of Cell Biology (2001)

671 Citations

Asymmetric CLASP-Dependent Nucleation of Noncentrosomal Microtubules at the trans-Golgi Network

Andrey Efimov;Alexey Kharitonov;Nadia Efimova;Jadranka Loncarek.
Developmental Cell (2007)

498 Citations

The dynamic kinetochore-microtubule interface.

Helder Maiato;Jennifer DeLuca;E. D. Salmon;William C. Earnshaw.
Journal of Cell Science (2004)

491 Citations

Kinetochore-driven formation of kinetochore fibers contributes to spindle assembly during animal mitosis

Helder Maiato;Conly L. Rieder;Conly L. Rieder;Conly L. Rieder;Alexey Khodjakov;Alexey Khodjakov;Alexey Khodjakov.
Journal of Cell Biology (2004)

310 Citations

Human CLASP1 Is an Outer Kinetochore Component that Regulates Spindle Microtubule Dynamics

Helder Maiato;Helder Maiato;Elizabeth A.L. Fairley;Conly L. Rieder;Jason R. Swedlow.
Cell (2003)

237 Citations

Drosophila CLASP is required for the incorporation of microtubule subunits into fluxing kinetochore fibres

Helder Maiato;Alexey Khodjakov;Alexey Khodjakov;Alexey Khodjakov;Conly L. Rieder;Conly L. Rieder;Conly L. Rieder.
Nature Cell Biology (2005)

206 Citations

Microtubule detyrosination guides chromosomes during mitosis

Marin Barisic;Ricardo Silva e Sousa;Suvranta K. Tripathy;Maria M. Magiera.
Science (2015)

189 Citations

MAST/Orbit has a role in microtubule–kinetochore attachment and is essential for chromosome alignment and maintenance of spindle bipolarity

Helder Maiato;Paula Sampaio;Catarina L. Lemos;John Findlay.
Journal of Cell Biology (2002)

145 Citations

Mitotic spindle multipolarity without centrosome amplification

Helder Maiato;Elsa Logarinho.
Nature Cell Biology (2014)

139 Citations

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