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Biology and Biochemistry

D-Index
69
Citations
17595
World Ranking
7362
National Ranking
190

Overview

Niels Galjart is a researcher affiliated with Erasmus University Rotterdam in the Netherlands. Their work primarily spans the fields of Biochemistry, Genetics, and Molecular Biology, with additional contributions to Medicine. The subfields that characterize their research include Molecular Biology, Cell Biology, Genetics, Cardiology and Cardiovascular Medicine, and Plant Science.

The main topics of focus in Galjart's research include:

  • Genomics and Chromatin Dynamics
  • Epigenetics and DNA Methylation
  • Microtubule and mitosis dynamics
  • RNA Research and Splicing
  • Cardiac electrophysiology and arrhythmias
  • Ion channel regulation and function
  • Acute Lymphoblastic Leukemia research

Among their published papers, notable recent works include:

  • "CTCF chromatin residence time controls three-dimensional genome organization, gene expression and DNA methylation in pluripotent cells," 2021, Nature Cell Biology
  • "Chromatin jets define the properties of cohesin-driven in vivo loop extrusion," 2022, Molecular Cell
  • "Targeting the Microtubule EB1-CLASP2 Complex Modulates Na V 1.5 at Intercalated Discs," 2021, Circulation Research
  • "The +TIP Navigator-1 is an actin-microtubule crosslinker that regulates axonal growth cone motility," 2020, The Journal of Cell Biology
  • "Novel TUBA4A Variant Associated With Familial Frontotemporal Dementia," 2021, Neurology Genetics

Galjart has collaborated frequently with several researchers, including:

  • Sreya Basu
  • Wilfred F. J. van IJcken
  • Mirjam C. G. N. van den Hout
  • Ihor Smal
  • Willem K. Smits

Their work is also represented across a range of academic publication venues with multiple papers appearing in:

  • The Journal of Cell Biology
  • Cell Reports
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Cell Biology
  • Molecular Cell

Best Publications

  • In vivo imaging of haematopoietic cells emerging from the mouse aortic endothelium

    Jean-Charles Boisset;Wiggert van Cappellen;Charlotte Andrieu-Soler;Niels Galjart

  • CTCF mediates long-range chromatin looping and local histone modification in the β-globin locus

    Erik Splinter;Helen Heath;Jurgen Kooren;Robert-Jan Palstra

  • Visualization of Microtubule Growth in Cultured Neurons via the Use of EB3-GFP (End-Binding Protein 3-Green Fluorescent Protein)

    Tatiana Stepanova;Jenny Slemmer;Casper C. Hoogenraad;Gideon Lansbergen

  • Clasps are CLIP-115 and -170 associating proteins involved in the regional regulation of microtubule dynamics in motile fibroblasts.

    Anna Akhmanova;Casper C. Hoogenraad;Ksenija Drabek;Tatiana Stepanova

  • Cohesin is positioned in mammalian genomes by transcription, CTCF and Wapl

    Georg A. Busslinger;Georg A. Busslinger;Roman R. Stocsits;Petra Van Der Lelij;Elin Axelsson;Elin Axelsson

  • Asymmetric CLASP-Dependent Nucleation of Noncentrosomal Microtubules at the trans-Golgi Network

    Andrey Efimov;Alexey Kharitonov;Nadia Efimova;Jadranka Loncarek

  • Microcircuitry and function of the inferior olive

    C. I. De Zeeuw;J. I. Simpson;C. C. Hoogenraad;N. Galjart

  • CLASP1 and CLASP2 bind to EB1 and regulate microtubule plus-end dynamics at the cell cortex

    Yuko Mimori-Kiyosue;Ilya Grigoriev;Gideon Lansbergen;Hiroyuki Sasaki

  • Bicaudal-D regulates COPI-independent Golgi-ER transport by recruiting the dynein-dynactin motor complex.

    Theodoros Matanis;Anna Akhmanova;Phebe Wulf;Elaine Del Nery

  • Tubulin tyrosination is a major factor affecting the recruitment of CAP-Gly proteins at microtubule plus ends

    Leticia Peris;Manuel Thery;Julien Fauré;Yasmina Saoudi

  • Mammalian Golgi‐associated Bicaudal‐D2 functions in the dynein–dynactin pathway by interacting with these complexes

    Casper C. Hoogenraad;Anna Akhmanova;Steven A. Howell;Bjorn R. Dortland

  • Cytoplasmic linker proteins promote microtubule rescue in vivo.

    Yulia A. Komarova;Anna S. Akhmanova;Shin Ichiro Kojima;Niels Galjart

  • CLASPs Attach Microtubule Plus Ends to the Cell Cortex through a Complex with LL5β

    Gideon Lansbergen;Ilya Grigoriev;Yuko Mimori-Kiyosue;Toshihisa Ohtsuka

  • CTCF mediates long-range chromatin looping and local histone modification in the beta-globin locus

    Erik Splinter;Helen Heath;Jurgen Kooren;Robert-Jan Palstra

  • LIS1, CLIP-170's key to the dynein/dynactin pathway.

    Frédéric M. Coquelle;Michal Caspi;Fabrice P. Cordelières;Jim P. Dompierre

  • CLIPs and CLASPs and cellular dynamics

    Niels Galjart

  • Expression of cDNA encoding the human “protective protein≓ associated with lysosomal β-galactosidase and neuraminidase: Homology to yeast proteases

    Niels J. Galjart;Nynke Gillemans;Alan Harris;Gijsbertus T.J. van der Horst

  • EB1 and EB3 control CLIP dissociation from the ends of growing microtubules.

    Yulia A Komarova;Gideon Lansbergen;Niels Galjart;Frank Grosveld

  • Plus-End-Tracking Proteins and Their Interactions at Microtubule Ends

    Niels Galjart

  • Bicaudal D induces selective dynein-mediated microtubule minus end-directed transport.

    Casper C. Hoogenraad;Phebe Wulf;Natalia Schiefermeier;Tatiana Stepanova

Frequent Co-Authors

Frank Grosveld
Frank Grosveld Erasmus University Rotterdam
Anna Akhmanova
Anna Akhmanova Utrecht University
Casper C. Hoogenraad
Casper C. Hoogenraad Utrecht University
Helder Maiato
Helder Maiato University of Porto
Chris I. De Zeeuw
Chris I. De Zeeuw Erasmus University Rotterdam
Joseph E. Italiano
Joseph E. Italiano Boston Children's Hospital
Rainer Renkawitz
Rainer Renkawitz University of Giessen
Rob Willemsen
Rob Willemsen Erasmus University Rotterdam

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