Lei Chen

Overview

Best Publications

• Prediction and analysis of essential genes using the enrichments of gene ontology and KEGG pathways

  Lei Chen;Yu-Hang Zhang;ShaoPeng Wang;YunHua Zhang

  435
  Citations

• Predicting Anatomical Therapeutic Chemical (ATC) Classification of Drugs by Integrating Chemical-Chemical Interactions and Similarities

  Lei Chen;Wei-Ming Zeng;Yu-Dong Cai;Kai-Yan Feng

  267
  Citations

• Analysis of cancer-related lncRNAs using gene ontology and KEGG pathways

  Lei Chen;Yu-Hang Zhang;Guohui Lu;Tao Huang

  193
  Citations

• A similarity-based method for prediction of drug side effects with heterogeneous information.

  Xian Zhao;Lei Chen;Lei Chen;Jing Lu

  149
  Citations

• Prediction of Protein Domain with mRMR Feature Selection and Analysis

  Bi-Qing Li;Le-Le Hu;Lei Chen;Kai-Yan Feng

  137
  Citations

• Prediction of Protein-Protein Interaction Sites by Random Forest Algorithm with mRMR and IFS

  Bi-Qing Li;Kai-Yan Feng;Lei Chen;Tao Huang;Tao Huang

  130
  Citations

• Classification and Analysis of Regulatory Pathways Using Graph Property, Biochemical and Physicochemical Property, and Functional Property

  Tao Huang;Tao Huang;Lei Chen;Yu-Dong Cai;Kuo-Chen Chou

  119
  Citations

• Gene Ontology and KEGG Pathway Enrichment Analysis of a Drug Target-Based Classification System.

  Lei Chen;Chen Chu;Jing Lu;Xiangyin Kong

  112
  Citations

• Identify Key Sequence Features to Improve CRISPR sgRNA Efficacy

  Lei Chen;Shaopeng Wang;Yu-Hang Zhang;Jiarui Li

  109
  Citations

• Gene expression profiling gut microbiota in different races of humans.

  Lei Chen;Yu-Hang Zhang;Tao Huang;Yu-Dong Cai

  107
  Citations

• iATC-NRAKEL: an efficient multi-label classifier for recognizing anatomical therapeutic chemical classes of drugs

  Jian-Peng Zhou;Lei Chen;Lei Chen;Zi-Han Guo

  105
  Citations

• Predicting the network of substrate-enzyme-product triads by combining compound similarity and functional domain composition

  Lei Chen;Lei Chen;Kai-Yan Feng;Yu-Dong Cai;Kuo-Chen Chou

  102
  Citations

• Prediction and analysis of cell‑penetrating peptides using pseudo‑amino acid composition and random forest models

  Lei Chen;Lei Chen;Chen Chu;Tao Huang;Xiangyin Kong

  101
  Citations

• Identification of Drug-Drug Interactions Using Chemical Interactions

  Lei Chen;Chen Chu;Yu-Hang Zhang;Mingyue Zheng

  86
  Citations

• Analysis and prediction of drug-drug interaction by minimum redundancy maximum relevance and incremental feature selection.

  Lili Liu;Lei Chen;Yu-Hang Zhang;Lai Wei

  85
  Citations

• A hybrid method for prediction and repositioning of drug Anatomical Therapeutic Chemical classes

  Lei Chen;Jing Lu;Ning Zhang;Tao Huang

  84
  Citations

• Predicting Drug Side Effects with Compact Integration of Heterogeneous Networks

  Xian Zhao;Lei Chen;Zi-Han Guo;Tao Liu

  81
  Citations

• Determining protein-protein functional associations by functional rules based on gene ontology and KEGG pathway.

  Yu-Hang Zhang;Yu-Hang Zhang;Tao Zeng;Lei Chen;Tao Huang

  76
  Citations

• iATC-FRAKEL: a simple multi-label web server for recognizing anatomical therapeutic chemical classes of drugs with their fingerprints only.

  Jian-Peng Zhou;Lei Chen;Lei Chen;Tianyun Wang;Min Liu

  76
  Citations

• Identification of compound-protein interactions through the analysis of gene ontology, KEGG enrichment for proteins and molecular fragments of compounds.

  Lei Chen;Yu-Hang Zhang;Mingyue Zheng;Tao Huang

  70
  Citations

• Signal propagation in protein interaction network during colorectal cancer progression.

  Yang Jiang;Tao Huang;Lei Chen;Yu-Fei Gao

  68
  Citations

• Identification of Differentially Expressed Genes between Original Breast Cancer and Xenograft Using Machine Learning Algorithms

  Deling Wang;Deling Wang;Jia-Rui Li;Yu-Hang Zhang;Lei Chen

  67
  Citations

• Tissue Expression Difference between mRNAs and lncRNAs.

  Lei Chen;Yu-Hang Zhang;Xiaoyong Pan;Min Liu

  65
  Citations