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Medicine

D-Index
107
Citations
45640
World Ranking
6207
National Ranking
3308

Research.com Recognitions

  • 2018 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2013 - Fellow, National Academy of Inventors

Overview

William S. Dalton is affiliated with the University of South Florida in the United States. Their research predominantly spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Within these, they have focused on subfields including Molecular Biology, Cancer Research, Oncology, Immunology, and Hematology.

The primary topics of Dalton's research include:

  • Cancer Genomics and Diagnostics
  • Cancer Immunotherapy and Biomarkers
  • Protein Degradation and Inhibitors
  • Multiple Myeloma Research and Treatments
  • Immune cells in cancer
  • Histone Deacetylase Inhibitors Research
  • Vaccines and immunoinformatics approaches

Dalton has contributed to several recent papers, reflecting ongoing involvement in cancer and immunology research. Notable publications include:

  • "Multiple Myeloma DREAM Challenge reveals epigenetic regulator PHF19 as marker of aggressive disease", 2020, Leukemia
  • "Plasma cell dependence on histone/protein deacetylase 11 reveals a therapeutic target in multiple myeloma", 2021, JCI Insight
  • "Jagged2 targeting in lung cancer activates anti-tumor immunity via Notch-induced functional reprogramming of tumor-associated macrophages", 2024, Immunity
  • "Incorporating long non-coding RNA (lncRNA) into genome-wide biomarker screening for prognostic gene signatures of immunotherapy outcomes.", 2023, Journal of Clinical Oncology
  • "Abstract IA27: An innovative approach to improve clinical trials using adaptive in silico design", 2020, Cancer Epidemiology Biomarkers & Prevention

They have frequently published in venues such as:

  • Regular and Young Investigator Award Abstracts
  • Leukemia
  • Immunity
  • JCI Insight
  • Journal of Clinical Oncology

Dalton's frequent collaborators include:

  • Ahmad A. Tarhini
  • Michelle L. Churchman
  • Aakrosh Ratan
  • Martin D. McCarter
  • John D. Carpten

Recognition of Dalton's contributions includes being named a Fellow of the American Association for the Advancement of Science (AAAS) in 2018 and as a Fellow of the National Academy of Inventors in 2013.

Best Publications

  • Bortezomib or high-dose dexamethasone for relapsed multiple myeloma

    Paul G. Richardson;Pieter Sonneveld;Michael W. Schuster;David Irwin

  • Criteria for the classification of monoclonal gammopathies, multiple myeloma and related disorders: a report of the International Myeloma Working Group

    Robert A. Kyle;J. Anthony Child;Kenneth Anderson;Bart Barlogie

  • Constitutive Activation of Stat3 Signaling Confers Resistance to Apoptosis in Human U266 Myeloma Cells

    Robyn Catlett-Falcone;Terry H Landowski;Marc M Oshiro;James Turkson

  • Donor leukocyte infusions in 140 patients with relapsed malignancy after allogeneic bone marrow transplantation.

    R H Collins;O Shpilberg;W R Drobyski;D L Porter

  • Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells.

    Tianhong Wang;Guilian Niu;Marcin Kortylewski;Lyudmila Burdelya

  • Cell Adhesion Mediated Drug Resistance (CAM-DR): Role of Integrins and Resistance to Apoptosis in Human Myeloma Cell Lines

    Jason S. Damiano;Anne E. Cress;Lori A. Hazlehurst;Lori A. Hazlehurst;Alexander A. Shtil;Alexander A. Shtil

  • Environment-mediated drug resistance: a major contributor to minimal residual disease

    Mark B. Meads;Robert A. Gatenby;William S. Dalton

  • MicroRNA-155 Is Regulated by the Transforming Growth Factor β/Smad Pathway and Contributes to Epithelial Cell Plasticity by Targeting RhoA

    William Kong;Hua Yang;Lili He;Jian Jun Zhao

  • Overexpression of a M(r) 110,000 vesicular protein in non-P-glycoprotein-mediated multidrug resistance.

    R.J. Scheper;H.J. Broxterman;G.L. Scheffer;P. Kaaijk

  • Drug-resistance in multiple myeloma and non-Hodgkin's lymphoma: detection of P-glycoprotein and potential circumvention by addition of verapamil to chemotherapy.

    W. S. Dalton;T. M. Grogan;P. S. Meltzer;R. J. Scheper

  • Extended follow-up of a phase 3 trial in relapsed multiple myeloma: final time-to-event results of the APEX trial.

    Paul Gerard Richardson;Pieter Sonneveld;Michael Schuster;David Irwin

  • A randomized phase 2 study of lenalidomide therapy for patients with relapsed or relapsed and refractory multiple myeloma

    Paul G. Richardson;Emily Blood;Constantine S. Mitsiades;Sundar Jagannath

  • The bone marrow microenvironment as a tumor sanctuary and contributor to drug resistance.

    Mark B. Meads;Lori A. Hazlehurst;William S. Dalton

  • Methods to Detect P-Glycoprotein-associated Multidrug Resistance in Patients' Tumors: Consensus Recommendations

    William T. Beck;Thomas M. Grogan;Cheryl L. Willman;Carlos Cordon-Cardo

  • Atypical multidrug resistance: breast cancer resistance protein messenger RNA expression in mitoxantrone-selected cell lines.

    Douglas D. Ross;Weidong Yang;Lynne V. Abruzzo;William S. Dalton

  • P-glycoprotein expression in malignant lymphoma and reversal of clinical drug resistance with chemotherapy plus high-dose verapamil.

    Thomas P. Miller;Thomas M. Grogan;William S. Dalton;Catherine M. Spier

  • Gene Therapy with Dominant-negative Stat3 Suppresses Growth of the Murine Melanoma B16 Tumor in Vivo

    Guilian Niu;Richard Heller;Robyn Catlett-Falcone;Domenico Coppola

  • Adhesion to fibronectin via beta1 integrins regulates p27kip1 levels and contributes to cell adhesion mediated drug resistance (CAM-DR).

    L A Hazlehurst;J S Damiano;I Buyuksal;W J Pledger

  • P-glycoprotein expression and function in circulating blood cells from normal volunteers

    Walter T. Klimecki;Bernard W. Futscher;Thomas M. Grogan;William S. Dalton

  • A genome-based model for adjusting radiotherapy dose (GARD): a retrospective, cohort-based study

    Jacob G Scott;Anders Berglund;Michael J Schell;Ivaylo Mihaylov

Frequent Co-Authors

Sydney E. Salmon
Sydney E. Salmon University of Arizona
Thomas M. Grogan
Thomas M. Grogan Roche (Switzerland)
Richard Jove
Richard Jove Nova Southeastern University
Claudio Anasetti
Claudio Anasetti Fred Hutchinson Cancer Research Center
John M. Koomen
John M. Koomen University of South Florida
Hua Yu
Hua Yu City Of Hope National Medical Center
Alan F. List
Alan F. List Precision BioSciences
Bernard W. Futscher
Bernard W. Futscher University of Arizona
Kenneth C. Anderson
Kenneth C. Anderson Harvard University
Paul G. Richardson
Paul G. Richardson Harvard University

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