D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Molecular Biology D-index 55 Citations 8,798 120 World Ranking 1578 National Ranking 796

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cancer
  • DNA

His primary scientific interests are in DNA methylation, Molecular biology, Epigenetics, Cancer research and Methylation. Bernard W. Futscher has included themes like Cancer, Breast cancer and Histone methyltransferase in his DNA methylation study. His Molecular biology research is multidisciplinary, incorporating perspectives in Chromatin, Gene, Mutation and RNA-Directed DNA Methylation.

His research in Epigenetics is mostly focused on Cancer epigenetics. The Cancer research study combines topics in areas such as Tumor suppressor gene and Carcinogenesis. His study looks at the relationship between Methylation and topics such as Gene expression, which overlap with Cell culture, CD19 and Bone marrow.

His most cited work include:

  • Role for DNA methylation in the control of cell type specific maspin expression. (400 citations)
  • P-glycoprotein expression and function in circulating blood cells from normal volunteers (321 citations)
  • Phase I/II trial of cyclosporine as a chemotherapy-resistance modifier in acute leukemia. (261 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Cancer research, DNA methylation, Molecular biology, Epigenetics and Carcinogenesis. His work carried out in the field of Cancer research brings together such families of science as Chromatin immunoprecipitation, Maspin, Metastasis, Tumor suppressor gene and Gene silencing. His DNA methylation study combines topics in areas such as Chromatin, Cancer and Methylation.

His Molecular biology research includes themes of Cell culture, Gene expression, Gene, DNA and O-6-methylguanine-DNA methyltransferase. Bernard W. Futscher combines subjects such as Malignant transformation, Regulation of gene expression and Histone with his study of Epigenetics. The study incorporates disciplines such as Mutation, Cell cycle, Telomerase and Polymerase chain reaction in addition to Carcinogenesis.

He most often published in these fields:

  • Cancer research (41.32%)
  • DNA methylation (39.67%)
  • Molecular biology (37.19%)

What were the highlights of his more recent work (between 2012-2020)?

  • Cancer research (41.32%)
  • DNA methylation (39.67%)
  • Cancer (19.83%)

In recent papers he was focusing on the following fields of study:

Cancer research, DNA methylation, Cancer, Carcinogenesis and Epigenetics are his primary areas of study. His Cancer research research includes elements of Pancreatic cancer, Pathology, Metastasis, Tumor progression and Gene silencing. His studies in DNA methylation integrate themes in fields like Gene expression profiling, microRNA, Disease and Carcinoma.

His Cancer research incorporates themes from Lung cancer and Methylation, DNA. His study in Epigenetics is interdisciplinary in nature, drawing from both Malignant transformation, Epigenetics of physical exercise and RNA-Directed DNA Methylation. His Gene research is multidisciplinary, incorporating perspectives in Molecular biology and Inflammatory breast cancer.

Between 2012 and 2020, his most popular works were:

  • miRNA Gene Promoters Are Frequent Targets of Aberrant DNA Methylation in Human Breast Cancer (105 citations)
  • Hypoxia perturbs aryl hydrocarbon receptor signaling and CYP1A1 expression induced by PCB 126 in human skin and liver-derived cell lines (50 citations)
  • Immortalization of normal human mammary epithelial cells in two steps by direct targeting of senescence barriers does not require gross genomic alterations. (47 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • DNA

Bernard W. Futscher focuses on Carcinogenesis, Cancer research, Epigenetics, Gene and DNA methylation. The various areas that Bernard W. Futscher examines in his Carcinogenesis study include Senescence, Cell aging, Small hairpin RNA, Telomerase and Transduction. The concepts of his Cancer research study are interwoven with issues in Tumor Virus, Semaphorin, Lymphangiogenesis, Tumor microenvironment and Transcriptome.

His Epigenetics research includes elements of Promoter, Gene silencing, microRNA and RNA-Directed DNA Methylation. His Gene study frequently draws connections between related disciplines such as Molecular biology. His research integrates issues of Mutation, Point mutation and DNA repair in his study of Molecular biology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Role for DNA methylation in the control of cell type specific maspin expression.

Bernard W. Futscher;Marc M. Oshiro;Ryan J. Wozniak;Nicholas Holtan.
Nature Genetics (2002)

574 Citations

P-glycoprotein expression and function in circulating blood cells from normal volunteers

Walter T. Klimecki;Bernard W. Futscher;Thomas M. Grogan;William S. Dalton.
Blood (1994)

446 Citations

Phase I/II trial of cyclosporine as a chemotherapy-resistance modifier in acute leukemia.

A F List;C Spier;J Greer;S Wolff.
Journal of Clinical Oncology (1993)

392 Citations

Role for DNA methylation in the regulation of miR-200c and miR-141 expression in normal and cancer cells.

Lukas Vrba;Taylor J. Jensen;James C. Garbe;Ronald L. Heimark.
PLOS ONE (2010)

359 Citations

Methylation of discrete regions of the O6-methylguanine DNA methyltransferase (MGMT) CpG island is associated with heterochromatinization of the MGMT transcription start site and silencing of the gene.

George S. Watts;Russell O. Pieper;Joseph F. Costello;Yei Mei Peng.
Molecular and Cellular Biology (1997)

302 Citations

Aberrant methylation of the BRCA1 CpG island promoter is associated with decreased BRCA1 mRNA in sporadic breast cancer cells

Judd C Rice;Kathy S Massey-Brown;Bernard W Futscher.
Oncogene (1998)

293 Citations

Methylation of the BRCA1 promoter is associated with decreased BRCA1 mRNA levels in clinical breast cancer specimens

Judd C. Rice;Hilmi Ozcelik;Hilmi Ozcelik;Patrick Maxeiner;Irene Andrulis;Irene Andrulis.
Carcinogenesis (2000)

280 Citations

Graded methylation in the promoter and body of the O6-methylguanine DNA methyltransferase (MGMT) gene correlates with MGMT expression in human glioma cells

Joseph F. Costello;Bernard W. Futscher;Keizo Tano;Dawn M. Graunke.
Journal of Biological Chemistry (1994)

253 Citations

Epigenetic silencing of maspin gene expression in human breast cancers.

Frederick E. Domann;Judd C. Rice;Mary J.C. Hendrix;Bernard W. Futscher.
International Journal of Cancer (2000)

241 Citations

5-Aza-2′-deoxycytidine-mediated reductions in G9A histone methyltransferase and histone H3 K9 di-methylation levels are linked to tumor suppressor gene reactivation

R J Wozniak;W T Klimecki;S S Lau;Y Feinstein.
Oncogene (2007)

221 Citations

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