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D-Index
99
Citations
31741
World Ranking
8678
National Ranking
4474

Overview

Michael P. Waalkes is a researcher affiliated with the National Institutes of Health in the United States. Their research focuses primarily on toxicology, molecular biology, and the mechanisms underlying cellular responses to environmental contaminants. The scientist's recent work has addressed topics such as heavy metal exposure and toxicity, epigenetics and DNA methylation, and arsenic contamination and mitigation.

Waalkes has contributed to several publications, including journal articles and research papers. Notable recent papers include:

  • Cadmium-stimulated invasion of rat liver cells during malignant transformation: Evidence of the involvement of oxidative stress/TET1-sensitive machinery, 2020, Toxicology
  • KRAS-retroviral fusion transcripts and gene amplification in arsenic-transformed, human prostate CAsE-PE cancer cells, 2020, Toxicology and Applied Pharmacology
  • Arsenic-induced malignant transformation of human keratinocytes: Involvement of Nrf2, 2020, UNC Libraries
  • Requirement of Arsenic Biomethylation for Oxidative DNA Damage, 2020, UNC Libraries
  • Corrigendum to "Regulatory role of KEAP1 and NRF2 in PPARg expression and chemoresistance in human non-small-cell lung carcinoma cells", 2021, Free Radical Biology and Medicine

The frequent coauthors with whom Waalkes has collaborated are:

  • Miroslav Stýblo
  • Erik J. Tokar
  • Bhalchandra A. Diwan
  • Jie Liu
  • Zuzana Drobná

Waalkes's research has been published largely in the following venues:

  • UNC Libraries
  • Toxicology
  • Toxicology and Applied Pharmacology
  • Free Radical Biology and Medicine

The main subfields of study represented in Waalkes's work include:

  • Molecular Biology
  • Health, Toxicology and Mutagenesis
  • Nutrition and Dietetics
  • Environmental Chemistry

Key research topics covered in their publications are:

  • Heavy Metal Exposure and Toxicity
  • Epigenetics and DNA Methylation
  • Trace Elements in Health
  • Arsenic contamination and mitigation
  • Advanced biosensing and bioanalysis techniques
  • DNA Repair Mechanisms

This profile reflects the scientist's contributions to understanding the biochemical and molecular bases of toxic exposures and their implications for human health, emphasizing environmental factors and their cellular impact. Their collaborative work spans multiple disciplines and contributes to ongoing research in toxicology and molecular biology.

Best Publications

  • Cadmium carcinogenesis in review.

    Michael P Waalkes

  • Arsenic: health effects, mechanisms of actions, and research issues.

    C O Abernathy;Y P Liu;D Longfellow;H V Aposhian

  • Association of Arsenic-Induced Malignant Transformation with DNA Hypomethylation and Aberrant Gene Expression

    Christopher Q. Zhao;Matthew R. Young;Bhalchandra A. Diwan;Timothy P. Coogan

  • Effects of cadmium on DNA-(Cytosine-5) methyltransferase activity and DNA methylation status during cadmium-induced cellular transformation.

    Masufumi Takiguchi;William E Achanzar;Wei Qu;Guying Li

  • Cadmium-induced Cancers in Animals and in Humans

    James Huff;Ruth M. Lunn;Michael P. Waalkes;Lorenzo Tomatis

  • Transplacental carcinogenicity of inorganic arsenic in the drinking water: induction of hepatic, ovarian, pulmonary, and adrenal tumors in mice.

    Michael P Waalkes;Jerrold M Ward;Jie Liu;Bhalchandra A Diwan

  • Toxicology of cadmium

    P. L. Goering;M. P. Waalkes;C. D. Klaassen

  • Liver is a target of arsenic carcinogenesis.

    Jie Liu;Michael P. Waalkes

  • Toxicological Principles of Metal Carcinogenesis with Special Emphasis on Cadmium

    Michael P. Waalkes;Timothy P. Coogan;Robert A. Barter

  • The enigma of arsenic carcinogenesis: role of metabolism.

    P L Goering;H V Aposhian;M J Mass;M Cebrián

  • Lead as a carcinogen: experimental evidence and mechanisms of action.

    Ellen K. Silbergeld;Michael Waalkes;Jerry M. Rice

  • Chronic inorganic arsenic exposure induces hepatic global and individual gene hypomethylation: implications for arsenic hepatocarcinogenesis

    Hua Chen;Shuan Fang Li;Jie Liu;Bhalchandra A. Diwan

  • Chronic arsenic poisoning from burning high-arsenic-containing coal in Guizhou, China.

    Jie Liu;Baoshan Zheng;H Vasken Aposhian;Yunshu Zhou

  • 24-norUrsodeoxycholic Acid Is Superior to Ursodeoxycholic Acid in the Treatment of Sclerosing Cholangitis in Mdr2 (Abcb4) Knockout Mice

    Peter Fickert;Martin Wagner;Hanns–Ulrich Marschall;Andrea Fuchsbichler

  • Cadmium and cancer of prostate and testis.

    Robert A. Goyer;Jie Liu;Michael P. Waalkes

  • Arsenic and Environmental Health: State of the Science and Future Research Opportunities

    Danielle J. Carlin;Marisa F. Naujokas;Karen D. Bradham;John Cowden

  • Mineral arsenicals in traditional medicines: orpiment, realgar, and arsenolite

    Jie Liu;Yuanfu Lu;Qin Wu;Robert A Goyer

  • Arsenic transport by the human multidrug resistance protein 1 (MRP1/ABCC1). Evidence that a tri-glutathione conjugate is required.

    Elaine M. Leslie;Anass Haimeur;Michael P. Waalkes

  • Tumor suppressor gene inactivation during cadmium-induced malignant transformation of human prostate cells correlates with overexpression of de novo DNA methyltransferase.

    Lamia Benbrahim-Tallaa;Robert A. Waterland;Anna L. Dill;Mukta M. Webber

  • Mercury in Traditional Medicines: Is Cinnabar Toxicologically Similar to Common Mercurials?:

    Jie Liu;Jing-Zheng Shi;Li-Mei Yu;Robert A. Goyer

Frequent Co-Authors

Jie Liu
Jie Liu National Institutes of Health
Jerrold M. Ward
Jerrold M. Ward National Institutes of Health
Jingbo Pi
Jingbo Pi China Medical University
Joseph E. Saavedra
Joseph E. Saavedra National Institutes of Health
Kazimierz S. Kasprzak
Kazimierz S. Kasprzak National Institutes of Health
Curtis D. Klaassen
Curtis D. Klaassen University of Kansas
Ronald P. Mason
Ronald P. Mason National Institutes of Health
Larry K. Keefer
Larry K. Keefer Science Applications International Corporation (United States)
Yu-Ying He
Yu-Ying He Duke University
Carl D. Bortner
Carl D. Bortner National Institutes of Health

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