D-Index & Metrics Best Publications
Chemistry
Canada
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Chemistry D-index 71 Citations 16,258 256 World Ranking 3340 National Ranking 86

Research.com Recognitions

Awards & Achievements

2023 - Research.com Chemistry in Canada Leader Award

2010 - Fellow of the Royal Society of Canada Academy of Science

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • DNA
  • Gene

His primary areas of study are Arsenic, Biochemistry, Aptamer, DNA and Environmental chemistry. His Arsenic research is multidisciplinary, incorporating elements of Urine, Chromatography and Carcinogen. His work on Metabolism, Metabolite, Cysteine and Hemoglobin as part of general Biochemistry research is frequently linked to Homogeneous, bridging the gap between disciplines.

His Aptamer research entails a greater understanding of Molecular biology. His DNA study combines topics in areas such as Nucleic acid amplification technique, Biophysics, Nucleic acid and Nanotechnology. X. Chris Le works mostly in the field of Environmental chemistry, limiting it down to topics relating to Arsenic speciation and, in certain cases, Peer review, Electrospray mass spectrometry and Pollution, as a part of the same area of interest.

His most cited work include:

  • Rolling circle amplification: A versatile tool for chemical biology, materials science and medicine (474 citations)
  • Arsenic binding to proteins. (367 citations)
  • Arsenic speciation analysis. (316 citations)

What are the main themes of his work throughout his whole career to date?

X. Chris Le mainly focuses on Arsenic, Biochemistry, Chromatography, Environmental chemistry and Arsenite. He works in the field of Arsenic, namely Arsenate. X. Chris Le interconnects Roxarsone and Arsenic contamination of groundwater in the investigation of issues within Arsenate.

X. Chris Le studies Speciation which is a part of Environmental chemistry. His Capillary electrophoresis research includes elements of DNA, Fluorescence anisotropy, Laser-induced fluorescence and Aptamer. X. Chris Le focuses mostly in the field of DNA, narrowing it down to topics relating to Nucleic acid and, in certain cases, Biophysics and Small molecule.

He most often published in these fields:

  • Arsenic (37.08%)
  • Biochemistry (22.85%)
  • Chromatography (20.22%)

What were the highlights of his more recent work (between 2016-2021)?

  • Arsenic (37.08%)
  • Environmental chemistry (17.23%)
  • Nucleic acid (5.62%)

In recent papers he was focusing on the following fields of study:

Arsenic, Environmental chemistry, Nucleic acid, Biochemistry and Biophysics are his primary areas of study. His Arsenic study frequently draws connections to other fields, such as Inductively coupled plasma mass spectrometry. His work carried out in the field of Environmental chemistry brings together such families of science as Inhalation exposure, Adsorption, Water treatment, Copper and Mercury.

His Nucleic acid study incorporates themes from Nucleic acid amplification technique, Deoxyribozyme, Cas9, Primer and Genome editing. His Biophysics research also works with subjects such as

  • Fluorophore together with Oligonucleotide, Fluorescence anisotropy and Aptamer,
  • Small molecule which is related to area like NASBA, Recombinase Polymerase Amplification, Rolling circle replication, Endonuclease and Amplicon,
  • Loop-mediated isothermal amplification together with DNA polymerase, Polymerase and Chemiluminescence. His Arsenite study integrates concerns from other disciplines, such as Arsenate and Biotransformation.

Between 2016 and 2021, his most popular works were:

  • A microRNA-initiated DNAzyme motor operating in living cells (159 citations)
  • DNAzyme-Mediated Assays for Amplified Detection of Nucleic Acids and Proteins (75 citations)
  • Exponential Isothermal Amplification of Nucleic Acids and Assays for Proteins, Cells, Small Molecules, and Enzyme Activities: An EXPAR Example. (74 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • DNA
  • Gene

His primary areas of investigation include Arsenic, Nucleic acid, Cell biology, Biophysics and Biochemistry. His work deals with themes such as High-performance liquid chromatography, Chromatography, Inductively coupled plasma mass spectrometry and Speciation, which intersect with Arsenic. X. Chris Le has researched Cell biology in several fields, including In vitro, microRNA and DNA, Homologous recombination.

His DNA research is multidisciplinary, incorporating perspectives in Molecular biology, Nucleotide and Mutant. His research integrates issues of Fluorescence anisotropy, Loop-mediated isothermal amplification, Aptamer, Molecule and Small molecule in his study of Biophysics. His work on Proteins metabolism, Nucleic acid quantitation, Oxidation state and Methyltransferase as part of general Biochemistry study is frequently linked to Methyl group, therefore connecting diverse disciplines of science.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Rolling circle amplification: A versatile tool for chemical biology, materials science and medicine

M. Monsur Ali;Feng Li;Feng Li;Zhiqing Zhang;Zhiqing Zhang;Kaixiang Zhang;Kaixiang Zhang.
Chemical Society Reviews (2014)

748 Citations

Arsenic binding to proteins.

Shengwen Shen;Xing-Fang Li;William R. Cullen;Michael Weinfeld.
Chemical Reviews (2013)

608 Citations

Arsenic speciation analysis.

Zhilong Gong;Xiufen Lu;Mingsheng Ma;Corinna Watt.
Talanta (2002)

532 Citations

Speciation of key arsenic metabolic intermediates in human urine.

X. Chris Le;Xiufen Lu;Mingsheng Ma;William R. Cullen.
Analytical Chemistry (2000)

389 Citations

A microRNA-initiated DNAzyme motor operating in living cells

Hanyong Peng;Xing-Fang Li;Hongquan Zhang;X. Chris Le.
Nature Communications (2017)

365 Citations

DNA-Mediated Homogeneous Binding Assays for Nucleic Acids and Proteins

Hongquan Zhang;Feng Li;Brittany Dever;Xing-Fang Li.
Chemical Reviews (2013)

364 Citations

Occurrence of Monomethylarsonous Acid in Urine of Humans Exposed to Inorganic Arsenic

H. Vasken Aposhian;Eugen S. Gurzau;X. Chris Le;Anca Gurzau.
Chemical Research in Toxicology (2000)

347 Citations

Aptamer binding assays for proteins: The thrombin example-A review

Bin Deng;Yanwen Lin;Chuan Wang;Feng Li.
Analytica Chimica Acta (2014)

318 Citations

Selection and analytical applications of aptamers

Camille L.A. Hamula;Jeffrey W. Guthrie;Hongquan Zhang;Xing-Fang Li.
Trends in Analytical Chemistry (2006)

317 Citations

Binding-induced fluorescence turn-on assay using aptamer-functionalized silver nanocluster DNA probes.

Jingjing Li;Jingjing Li;Xiaoqin Zhong;Hongquan Zhang;X. Chris Le.
Analytical Chemistry (2012)

311 Citations

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