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Chemistry
Canada
2025

D-Index & Metrics

Chemistry

D-Index
83
Citations
23007
World Ranking
2966
National Ranking
66

X. Chris Le publication distribution in Chemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Chemistry in 2026. The highlighted bar marks where X. Chris Le sits on this spectrum.

61–80 publications: 66 scientists 81–100 publications: 302 scientists 101–120 publications: 623 scientists 121–140 publications: 918 scientists 141–160 publications: 1,218 scientists 161–180 publications: 1,350 scientists 181–200 publications: 1,344 scientists 201–220 publications: 1,281 scientists 221–240 publications: 1,216 scientists 241–260 publications: 1,100 scientists 261–280 publications: 979 scientists 281–300 publications: 939 scientists 301–320 publications: 764 scientists 321–340 publications: 643 scientists 341–360 publications: 628 scientists 361–380 publications: 522 scientists 381–400 publications: 459 scientists 401–420 publications: 397 scientists 421–440 publications: 327 scientists 441–460 publications: 270 scientists 461–480 publications: 265 scientists 481–500 publications: 252 scientists 501–520 publications: 201 scientists 521–540 publications: 185 scientists 541–560 publications: 148 scientists 561–580 publications: 148 scientists 581–600 publications: 132 scientists 601–620 publications: 114 scientists 621–640 publications: 104 scientists 641–660 publications: 91 scientists 661–680 publications: 92 scientists 681–700 publications: 73 scientists 701–720 publications: 57 scientists 721–740 publications: 54 scientists 741–760 publications: 67 scientists 761–780 publications: 45 scientists 781–800 publications: 46 scientists 801–820 publications: 39 scientists 821–840 publications: 32 scientists 841–860 publications: 36 scientists 861–880 publications: 29 scientists 881–900 publications: 26 scientists 901–920 publications: 24 scientists 921–940 publications: 14 scientists 941–960 publications: 23 scientists 961–980 publications: 28 scientists 981–1,000 publications: 15 scientists 1,001–1,020 publications: 29 scientists 1,021–1,040 publications: 12 scientists 1,041–1,060 publications: 19 scientists 1,061–1,080 publications: 12 scientists 1,081–1,100 publications: 6 scientists 1,101–1,120 publications: 8 scientists 1,121–1,140 publications: 12 scientists 1,141–1,160 publications: 5 scientists 1,161–1,180 publications: 6 scientists 1,181–1,200 publications: 14 scientists 1,201–1,220 publications: 7 scientists 1,221–1,240 publications: 2 scientists 1,241–1,260 publications: 6 scientists 1,261–1,280 publications: 4 scientists 1,281–1,294 publications: 6 scientists 1,295+ publications: 100 scientists
61 publications 1,295+

This scientist: 292 publications — 61st percentile

61% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,295 publications or more.

X. Chris Le D-index placement in Chemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Chemistry scientists ranked by Research.com in 2026. The highlighted bar marks where X. Chris Le sits on this spectrum.

40–41 D-Index: 289 scientists 42–43 D-Index: 612 scientists 44–45 D-Index: 808 scientists 46–47 D-Index: 776 scientists 48–49 D-Index: 835 scientists 50–51 D-Index: 861 scientists 52–53 D-Index: 872 scientists 54–55 D-Index: 933 scientists 56–57 D-Index: 1,051 scientists 58–59 D-Index: 930 scientists 60–61 D-Index: 882 scientists 62–63 D-Index: 834 scientists 64–65 D-Index: 731 scientists 66–67 D-Index: 775 scientists 68–69 D-Index: 683 scientists 70–71 D-Index: 646 scientists 72–73 D-Index: 561 scientists 74–75 D-Index: 501 scientists 76–77 D-Index: 437 scientists 78–79 D-Index: 388 scientists 80–81 D-Index: 354 scientists 82–83 D-Index: 292 scientists 84–85 D-Index: 275 scientists 86–87 D-Index: 254 scientists 88–89 D-Index: 235 scientists 90–91 D-Index: 185 scientists 92–93 D-Index: 192 scientists 94–95 D-Index: 155 scientists 96–97 D-Index: 163 scientists 98–99 D-Index: 125 scientists 100–101 D-Index: 105 scientists 102–103 D-Index: 105 scientists 104–105 D-Index: 112 scientists 106–107 D-Index: 88 scientists 108–109 D-Index: 68 scientists 110–111 D-Index: 69 scientists 112–113 D-Index: 65 scientists 114–115 D-Index: 79 scientists 116–117 D-Index: 61 scientists 118–119 D-Index: 44 scientists 120–121 D-Index: 37 scientists 122–123 D-Index: 40 scientists 124–125 D-Index: 33 scientists 126–127 D-Index: 26 scientists 128–129 D-Index: 34 scientists 130–131 D-Index: 35 scientists 132–133 D-Index: 25 scientists 134–135 D-Index: 27 scientists 136–137 D-Index: 17 scientists 138–139 D-Index: 16 scientists 140–141 D-Index: 20 scientists 142–143 D-Index: 20 scientists 144–145 D-Index: 15 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 9 scientists 150–151 D-Index: 16 scientists 152–153 D-Index: 11 scientists 154–155 D-Index: 9 scientists 156–157 D-Index: 3 scientists 158 D-Index: 3 scientists 159+ D-Index: 98 scientists
40 D-Index 159+

This scientist: 83 D-Index — 84th percentile

84% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 159 D-Index or more.

Research.com Recognitions

  • 2025 - Research.com Chemistry in Canada Leader Award
  • 2022 - Research.com Chemistry in Canada Leader Award
  • 2010 - Fellow of the Royal Society of Canada Academy of Science

Overview

X. Chris Le is affiliated with the University of Alberta in Canada and has a significant body of research in biochemistry, genetics, molecular biology, and environmental science. Their work spans multiple subfields including molecular biology, infectious diseases, biomedical engineering, health toxicology, mutagenesis, and environmental chemistry.

Their research topics cover advanced biosensing and bioanalysis techniques, biosensors and analytical detection, CRISPR and genetic engineering, SARS-CoV-2 detection and testing, arsenic contamination and mitigation, heavy metal exposure and toxicity, and RNA interference and gene delivery.

Frequent co-authors collaborating with X. Chris Le include:

  • Hongquan Zhang
  • Hanyong Peng
  • Wei Feng
  • Xing-Fang Li
  • Jeffrey Tao

Their work has been published extensively in several scientific venues, with notable frequency in:

  • Analytical Chemistry
  • Journal of Environmental Sciences
  • Angewandte Chemie International Edition
  • Angewandte Chemie
  • Environmental Science & Technology

Some of the recent publications authored or coauthored by X. Chris Le include:

  • "Molecular Diagnosis of COVID-19: Challenges and Research Needs," 2020, Analytical Chemistry
  • "CRISPR technology incorporating amplification strategies: molecular assays for nucleic acids, proteins, and small molecules," 2021, Chemical Science
  • "Isothermal Amplification and Ambient Visualization in a Single Tube for the Detection of SARS-CoV-2 Using Loop-Mediated Amplification and CRISPR Technology," 2020, Analytical Chemistry
  • "The CRISPR-Cas toolbox for analytical and diagnostic assay development," 2021, Chemical Society Reviews
  • "Integrating Reverse Transcription Recombinase Polymerase Amplification with CRISPR Technology for the One-Tube Assay of RNA," 2021, Analytical Chemistry

X. Chris Le was awarded the Fellow of the Royal Society of Canada by the Academy of Science in 2010. This recognition highlights their contributions within the scientific community.

Best Publications

  • Rolling circle amplification: A versatile tool for chemical biology, materials science and medicine

    M. Monsur Ali;Feng Li;Feng Li;Zhiqing Zhang;Zhiqing Zhang;Kaixiang Zhang;Kaixiang Zhang

  • Arsenic binding to proteins.

    Shengwen Shen;Xing-Fang Li;William R. Cullen;Michael Weinfeld

  • Arsenic speciation analysis.

    Zhilong Gong;Xiufen Lu;Mingsheng Ma;Corinna Watt

  • A microRNA-initiated DNAzyme motor operating in living cells

    Hanyong Peng;Xing-Fang Li;Hongquan Zhang;X. Chris Le

  • DNA-Mediated Homogeneous Binding Assays for Nucleic Acids and Proteins

    Hongquan Zhang;Feng Li;Brittany Dever;Xing-Fang Li

  • Speciation of key arsenic metabolic intermediates in human urine.

    X. Chris Le;Xiufen Lu;Mingsheng Ma;William R. Cullen

  • Aptamer binding assays for proteins: The thrombin example-A review

    Bin Deng;Yanwen Lin;Chuan Wang;Feng Li

  • Molecular Diagnosis of COVID-19: Challenges and Research Needs.

    Wei Feng;Ashley M. Newbigging;Connie Le;Bo Pang

  • Selection and analytical applications of aptamers

    Camille L.A. Hamula;Jeffrey W. Guthrie;Hongquan Zhang;Xing-Fang Li

  • Biotransformation of arsenic by a Yellowstone thermoacidophilic eukaryotic alga.

    Jie Qin;Corinne R. Lehr;Chungang Yuan;X. Chris Le

  • Binding-induced fluorescence turn-on assay using aptamer-functionalized silver nanocluster DNA probes.

    Jingjing Li;Jingjing Li;Xiaoqin Zhong;Hongquan Zhang;X. Chris Le

  • Exponential Isothermal Amplification of Nucleic Acids and Assays for Proteins, Cells, Small Molecules, and Enzyme Activities: An EXPAR Example.

    Michael S. Reid;X. Chris Le;Hongquan Zhang

  • Electrochemical DNAzyme Sensor for Lead Based on Amplification of DNA−Au Bio-Bar Codes

    Li Shen;Zhong Chen;Yihan Li;Shali He

  • Occurrence of monomethylarsonous acid in urine of humans exposed to inorganic arsenic.

    Unknown

  • CRISPR technology incorporating amplification strategies: molecular assays for nucleic acids, proteins, and small molecules

    Wei Feng;Ashley M. Newbigging;Jeffrey Tao;Yiren Cao

  • Inducible repair of thymine glycol detected by an ultrasensitive assay for DNA damage.

    X. Chris Le;X. Chris Le;X. Chris Le;James Z. Xing;James Z. Xing;James Z. Xing;Jane Lee;Jane Lee;Jane Lee;Steven A. Leadon;Steven A. Leadon;Steven A. Leadon

  • Speciation of Submicrogram per Liter Levels of Arsenic in Water: On-Site Species Separation Integrated with Sample Collection

    X. Chris Le;Serife Yalcin;Mingsheng Ma

  • Determination of monomethylarsonous acid, a key arsenic methylation intermediate, in human urine.

    X C Le;M Ma;W R Cullen;H V Aposhian

  • Unstable trivalent arsenic metabolites, monomethylarsonous acid and dimethylarsinous acid

    Zhilong Gong;Xiufen Lu;William R. Cullen;X. Chris Le

  • Effect of arsenosugar ingestion on urinary arsenic speciation

    Mingsheng Ma;X. Chris Le

  • Isothermal Amplification and Ambient Visualization in a Single Tube for the Detection of SARS-CoV-2 Using Loop-Mediated Amplification and CRISPR Technology.

    Bo Pang;Jingyang Xu;Yanming Liu;Hanyong Peng

  • Excretion of arsenic in urine as a function of exposure to arsenic in drinking water.

    R L Calderon;E Hudgens;X C Le;D Schreinemachers

  • Disruption of the Arsenic (+3 Oxidation State) Methyltransferase Gene in the Mouse Alters the Phenotype for Methylation of Arsenic and Affects Distribution and Retention of Orally Administered Arsenate

    Zuzana Drobna;Hua Naranmandura;Kevin M. Kubachka;Brenda C. Edwards

Frequent Co-Authors

Xing-Fang Li
Xing-Fang Li University of Alberta
Michael Weinfeld
Michael Weinfeld University of Alberta
Hailin Wang
Hailin Wang Chinese Academy of Sciences
Samuel Monroe Cohen
Samuel Monroe Cohen University of Nebraska Medical Center
William R. Cullen
William R. Cullen University of British Columbia
Lizhong Zhu
Lizhong Zhu Zhejiang University
Bin Hu
Bin Hu Wuhan University
D. Lorne Tyrrell
D. Lorne Tyrrell University of Alberta
David J. Thomas
David J. Thomas Environmental Protection Agency
Martin J. Zuidhof
Martin J. Zuidhof University of Alberta

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