Mahesh P. Gupta

Overview

Best Publications

• Geopolymer concrete: A review of some recent developments

  B. Singh;G. Ishwarya;M. Gupta;S.K. Bhattacharyya

  1290
  Citations

• Sirt3 blocks the cardiac hypertrophic response by augmenting Foxo3a-dependent antioxidant defense mechanisms in mice

  Nagalingam R. Sundaresan;Madhu Gupta;Gene Kim;Senthilkumar B. Rajamohan

  1073
  Citations

• SIRT3 Is a Stress-Responsive Deacetylase in Cardiomyocytes That Protects Cells from Stress-Mediated Cell Death by Deacetylation of Ku70

  Nagalingam R. Sundaresan;Sadhana A. Samant;Vinodkumar B. Pillai;Senthilkumar B. Rajamohan

  609
  Citations

• Cytokine production by maternal lymphocytes during normal human pregnancy and in unexplained recurrent spontaneous abortion

  R. Raghupathy;M. Makhseed;F. Azizieh;A. Omu

  596
  Citations

• Poly(ADP-ribose) Polymerase-1-dependent Cardiac Myocyte Cell Death during Heart Failure Is Mediated by NAD+ Depletion and Reduced Sir2α Deacetylase Activity *

  Jyothish B. Pillai;Ayman Isbatan;Shin Ichiro Imai;Mahesh P. Gupta

  473
  Citations

• The sirtuin SIRT6 blocks IGF-Akt signaling and development of cardiac hypertrophy by targeting c-Jun

  Nagalingam R. Sundaresan;Prabhakaran Vasudevan;Lei Zhong;Gene Kim

  466
  Citations

• Exogenous NAD Blocks Cardiac Hypertrophic Response via Activation of the SIRT3-LKB1-AMP-activated Kinase Pathway

  Vinodkumar B. Pillai;Nagalingam R. Sundaresan;Gene Kim;Madhu Gupta

  450
  Citations

• SIRT3 Deacetylates and Activates OPA1 To Regulate Mitochondrial Dynamics during Stress

  Sadhana A. Samant;Hannah J. Zhang;Zhigang Hong;Vinodkumar B. Pillai

  408
  Citations

• Honokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial Sirt3

  Vinodkumar B. Pillai;Sadhana Samant;Nagalingam R. Sundaresan;Hariharasundaram Raghuraman

  392
  Citations

• The Deacetylase SIRT1 Promotes Membrane Localization and Activation of Akt and PDK1 During Tumorigenesis and Cardiac Hypertrophy

  Nagalingam R. Sundaresan;Vinodkumar B. Pillai;Don Wolfgeher;Sadhana Samant

  338
  Citations

• SIRT1 Promotes Cell Survival under Stress by Deacetylation-Dependent Deactivation of Poly(ADP-Ribose) Polymerase 1

  Senthilkumar B. Rajamohan;Vinodkumar B. Pillai;Madhu Gupta;Nagalingam R. Sundaresan

  337
  Citations

• Factors controlling cardiac myosin-isoform shift during hypertrophy and heart failure.

  Mahesh P. Gupta

  284
  Citations

• Regulation of Akt Signaling by Sirtuins Its Implication in Cardiac Hypertrophy and Aging

  Vinodkumar B. Pillai;Nagalingam R. Sundaresan;Mahesh P. Gupta

  267
  Citations

• Obesity-induced lysine acetylation increases cardiac fatty acid oxidation and impairs insulin signalling

  Osama Abo Alrob;Sowndramalingam Sankaralingam;Cary Ma;Cory S. Wagg

  213
  Citations

• HDAC4 and PCAF bind to cardiac sarcomeres and play a role in regulating myofilament contractile activity.

  Mahesh P. Gupta;Sadhana A. Samant;Stephen H. Smith;Sanjeev G. Shroff

  197
  Citations

• SIRT3 Blocks Aging-Associated Tissue Fibrosis in Mice by Deacetylating and Activating Glycogen Synthase Kinase 3β.

  Nagalingam R. Sundaresan;Samik Bindu;Vinodkumar B. Pillai;Sadhana Samant

  180
  Citations

• Calcium/calmodulin-dependent protein kinase activates serum response factor transcription activity by its dissociation from histone deacetylase, HDAC4. Implications in cardiac muscle gene regulation during hypertrophy.

  Francesca J. Davis;Madhu Gupta;Madhu Gupta;Blanca Camoretti-Mercado;Robert J. Schwartz

  176
  Citations

• Egr-1, a serum-inducible zinc finger protein, regulates transcription of the rat cardiac alpha-myosin heavy chain gene.

  M P Gupta;M Gupta;R Zak;V P Sukhatme

  165
  Citations

• A Novel Cardiomyocyte-enriched MicroRNA, miR-378, Targets Insulin-like Growth Factor 1 Receptor IMPLICATIONS IN POSTNATAL CARDIAC REMODELING AND CELL SURVIVAL

  Ivana Knezevic;Aalok Patel;Nagalingam R. Sundaresan;Mahesh P. Gupta

  161
  Citations

• Honokiol, an activator of Sirtuin-3 (SIRT3) preserves mitochondria and protects the heart from doxorubicin-induced cardiomyopathy in mice

  Vinodkumar B. Pillai;Abhinav Kanwal;Yong Hu Fang;Willard W. Sharp

  161
  Citations