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Mahesh P. Gupta

D-Index & Metrics

Biology and Biochemistry

D-Index
51
Citations
12783
World Ranking
16986
National Ranking
7001

Mahesh P. Gupta publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Mahesh P. Gupta sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 413 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 848 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 949 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 840 scientists 207–216 publications: 733 scientists 217–226 publications: 708 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 417 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 196 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 59 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 157 publications — 30th percentile

30% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Mahesh P. Gupta D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Mahesh P. Gupta sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 316 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 899 scientists 52–53 D-Index: 1,025 scientists 54–55 D-Index: 1,149 scientists 56–57 D-Index: 1,235 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,162 scientists 62–63 D-Index: 1,130 scientists 64–65 D-Index: 1,031 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 714 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 71 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 51 D-Index — 14th percentile

14% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Mahesh P. Gupta is affiliated with the University of Chicago in the United States. Their research spans multiple domains within medicine and biochemistry, genetics, and molecular biology, with a focus on molecular mechanisms underlying disease and physiology.

Their main fields of study include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Gupta's research notably addresses several subfields such as:

  • Geriatrics and Gerontology
  • Molecular Biology
  • Physiology
  • Epidemiology
  • Cell Biology

Their work covers various topics including:

  • Sirtuins and Resveratrol in Medicine
  • Mitochondrial Function and Pathology
  • Adipose Tissue and Metabolism
  • Autophagy in Disease and Therapy
  • Endoplasmic Reticulum Stress and Disease
  • Muscle Physiology and Disorders
  • RNA modifications and cancer

Gupta has published research in several scientific venues. The most frequent publication venues include:

  • The FASEB Journal
  • Aging
  • American Journal of Physiology-Endocrinology and Metabolism
  • JCSM Rapid Communications
  • Circulation

Some recent papers authored or co-authored by Gupta include:

  • "The nuclear sirtuin SIRT6 protects the heart from developing aging-associated myocyte senescence and cardiac hypertrophy" (2021) published in Aging
  • "Is nuclear sirtuin SIRT6 a master regulator of immune function?" (2020) published in American Journal of Physiology-Endocrinology and Metabolism
  • "Skeletal muscle-specific over-expression of the nuclear sirtuin SIRT6 blocks cancer-associated cachexia by regulating multiple targets" (2020) published in JCSM Rapid Communications
  • "Characterization and molecular targeting of CFIm25 ( NUDT21/CPSF5 ) mRNA using miRNAs" (2025) published in The FASEB Journal
  • "Sirt6 activation blocks LPS induced expression of inflammatory cytokines in cardiac cells" (2022) published in The FASEB Journal

Frequent collaborators in Gupta's research include:

  • Sadhana Samant
  • Vinodkumar B. Pillai
  • Samantha Hund
  • Madhu Gupta
  • Chioniso Patience Masamha

The work of Mahesh P. Gupta reveals an emphasis on the role of sirtuins, particularly SIRT6, in various physiological and pathological processes such as aging, immune regulation, muscle physiology, and inflammation. Their research contributions also extend into molecular biology aspects related to RNA regulation and cancer.

Best Publications

  • Geopolymer concrete: A review of some recent developments

    B. Singh;G. Ishwarya;M. Gupta;S.K. Bhattacharyya

  • Sirt3 blocks the cardiac hypertrophic response by augmenting Foxo3a-dependent antioxidant defense mechanisms in mice

    Nagalingam R. Sundaresan;Madhu Gupta;Gene Kim;Senthilkumar B. Rajamohan

  • SIRT3 Is a Stress-Responsive Deacetylase in Cardiomyocytes That Protects Cells from Stress-Mediated Cell Death by Deacetylation of Ku70

    Nagalingam R. Sundaresan;Sadhana A. Samant;Vinodkumar B. Pillai;Senthilkumar B. Rajamohan

  • Cytokine production by maternal lymphocytes during normal human pregnancy and in unexplained recurrent spontaneous abortion

    R. Raghupathy;M. Makhseed;F. Azizieh;A. Omu

  • Poly(ADP-ribose) Polymerase-1-dependent Cardiac Myocyte Cell Death during Heart Failure Is Mediated by NAD+ Depletion and Reduced Sir2α Deacetylase Activity *

    Jyothish B. Pillai;Ayman Isbatan;Shin Ichiro Imai;Mahesh P. Gupta

  • The sirtuin SIRT6 blocks IGF-Akt signaling and development of cardiac hypertrophy by targeting c-Jun

    Nagalingam R. Sundaresan;Prabhakaran Vasudevan;Lei Zhong;Gene Kim

  • Exogenous NAD Blocks Cardiac Hypertrophic Response via Activation of the SIRT3-LKB1-AMP-activated Kinase Pathway

    Vinodkumar B. Pillai;Nagalingam R. Sundaresan;Gene Kim;Madhu Gupta

  • SIRT3 Deacetylates and Activates OPA1 To Regulate Mitochondrial Dynamics during Stress

    Sadhana A. Samant;Hannah J. Zhang;Zhigang Hong;Vinodkumar B. Pillai

  • Honokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial Sirt3

    Vinodkumar B. Pillai;Sadhana Samant;Nagalingam R. Sundaresan;Hariharasundaram Raghuraman

  • The Deacetylase SIRT1 Promotes Membrane Localization and Activation of Akt and PDK1 During Tumorigenesis and Cardiac Hypertrophy

    Nagalingam R. Sundaresan;Vinodkumar B. Pillai;Don Wolfgeher;Sadhana Samant

  • SIRT1 Promotes Cell Survival under Stress by Deacetylation-Dependent Deactivation of Poly(ADP-Ribose) Polymerase 1

    Senthilkumar B. Rajamohan;Vinodkumar B. Pillai;Madhu Gupta;Nagalingam R. Sundaresan

  • Factors controlling cardiac myosin-isoform shift during hypertrophy and heart failure.

    Mahesh P. Gupta

  • Regulation of Akt Signaling by Sirtuins Its Implication in Cardiac Hypertrophy and Aging

    Vinodkumar B. Pillai;Nagalingam R. Sundaresan;Mahesh P. Gupta

  • Obesity-induced lysine acetylation increases cardiac fatty acid oxidation and impairs insulin signalling

    Osama Abo Alrob;Sowndramalingam Sankaralingam;Cary Ma;Cory S. Wagg

  • HDAC4 and PCAF bind to cardiac sarcomeres and play a role in regulating myofilament contractile activity.

    Mahesh P. Gupta;Sadhana A. Samant;Stephen H. Smith;Sanjeev G. Shroff

  • SIRT3 Blocks Aging-Associated Tissue Fibrosis in Mice by Deacetylating and Activating Glycogen Synthase Kinase 3β.

    Nagalingam R. Sundaresan;Samik Bindu;Vinodkumar B. Pillai;Sadhana Samant

  • Calcium/calmodulin-dependent protein kinase activates serum response factor transcription activity by its dissociation from histone deacetylase, HDAC4. Implications in cardiac muscle gene regulation during hypertrophy.

    Francesca J. Davis;Madhu Gupta;Madhu Gupta;Blanca Camoretti-Mercado;Robert J. Schwartz

  • Egr-1, a serum-inducible zinc finger protein, regulates transcription of the rat cardiac alpha-myosin heavy chain gene.

    M P Gupta;M Gupta;R Zak;V P Sukhatme

  • A Novel Cardiomyocyte-enriched MicroRNA, miR-378, Targets Insulin-like Growth Factor 1 Receptor IMPLICATIONS IN POSTNATAL CARDIAC REMODELING AND CELL SURVIVAL

    Ivana Knezevic;Aalok Patel;Nagalingam R. Sundaresan;Mahesh P. Gupta

  • Honokiol, an activator of Sirtuin-3 (SIRT3) preserves mitochondria and protects the heart from doxorubicin-induced cardiomyopathy in mice

    Vinodkumar B. Pillai;Abhinav Kanwal;Yong Hu Fang;Willard W. Sharp

Frequent Co-Authors

Jack L. Arbiser
Jack L. Arbiser Emory University
R. John Solaro
R. John Solaro University of Illinois at Chicago
Mahavir Singh
Mahavir Singh Indian Institute of Science
Joe G.N. Garcia
Joe G.N. Garcia University of Arizona
Raul Mostoslavsky
Raul Mostoslavsky Harvard University
David W. Kamp
David W. Kamp Northwestern University
Alexandre F.R. Stewart
Alexandre F.R. Stewart University of Ottawa
Eric Verdin
Eric Verdin Buck Institute for Research on Aging
Yingming Zhao
Yingming Zhao University of Chicago
Chu-Xia Deng
Chu-Xia Deng University of Macau

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