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Alexandre F.R. Stewart

Alexandre F.R. Stewart

D-Index & Metrics

Biology and Biochemistry

D-Index
75
Citations
37765
World Ranking
5188
National Ranking
188

Overview

Alexandre F.R. Stewart is affiliated with the University of Ottawa in Canada and has contributed extensively to research in the fields of Medicine, Neuroscience, and Biochemistry, Genetics and Molecular Biology. Their work spans multiple subfields including Molecular Biology, Cellular and Molecular Neuroscience, Cardiology and Cardiovascular Medicine, Epidemiology, and Neurology.

Stewart's main research topics include Neuroinflammation and Neurodegeneration Mechanisms, Neuroscience and Neuropharmacology Research, Congenital Heart Disease Studies, Protein Tyrosine Phosphatases, Alzheimer's disease research and treatments, Congenital heart defects research, and Biochemical Analysis and Sensing Techniques.

Frequent publication venues for their research are:

  • Circulation
  • Neural Regeneration Research
  • PLoS Genetics
  • Neurobiology of Disease
  • UNC Libraries

Notable recent papers authored or co-authored by Stewart include:

  • Neuronal Protein Tyrosine Phosphatase 1B Hastens Amyloid β-Associated Alzheimer's Disease in Mice, 2020, Journal of Neuroscience
  • Genome-wide meta-analyses of restless legs syndrome yield insights into genetic architecture, disease biology and risk prediction, 2024, Nature Genetics
  • Hyperactivated PTP1B phosphatase in parvalbumin neurons alters anterior cingulate inhibitory circuits and induces autism-like behaviors, 2020, Nature Communications
  • Integrative analysis of genomic variants reveals new associations of candidate haploinsufficient genes with congenital heart disease, 2021, PLoS Genetics
  • Tyrosine phosphatase PTP1B impairs presynaptic NMDA receptor-mediated plasticity in a mouse model of Alzheimer's disease, 2021, Neurobiology of Disease

Frequent co-authors collaborating with Stewart are:

  • Hsiao-Huei Chen
  • Zhaohong Qin
  • Konrad M. Ricke
  • Michael Zasloff
  • Ragnar O. Vilmundarson

Best Publications

  • Strengthening the reporting of genetic association studies (STREGA): an extension of the STROBE statement

    Julian Little;Julian P.T. Higgins;John P.A. Ioannidis;John P.A. Ioannidis;David Moher

  • Plasma HDL cholesterol and risk of myocardial infarction: A mendelian randomisation study

    Benjamin F. Voight;Benjamin F. Voight;Benjamin F. Voight;Gina M. Peloso;Gina M. Peloso;Marju Orho-Melander;Ruth Frikke-Schmidt

  • A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease

    M Nikpay;A Goel;Won H-H.;L M Hall

  • Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

    Heribert Schunkert;Inke R. König;Sekar Kathiresan;Muredach P. Reilly

  • Aptamer-based multiplexed proteomic technology for biomarker discovery

    Larry Gold;Deborah Ayers;Jennifer Bertino;Christopher Bock

  • Large-scale association analysis identifies new risk loci for coronary artery disease

    Panos Deloukas;Stavroula Kanoni;Christina Willenborg;Martin Farrall

  • A common allele on chromosome 9 associated with coronary heart disease

    Ruth Mcpherson;Alexander Pertsemlidis;Nihan Kavaslar;Alexandre Stewart

  • Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction

    Ron Do;Ron Do;Nathan O. Stitziel;Hong Hee Won;Hong Hee Won;Anders Berg Jørgensen

  • A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease

    Majid Nikpay;Anuj Goel;Hong-Hee Won;Leanne M. Hall

  • Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies

    Muredach P Reilly;Mingyao Li;Jing He;Jane F Ferguson

  • Somatic mutations in the connexin 40 gene (GJA5) in atrial fibrillation.

    Michael H Gollob;Douglas L Jones;Andrew D Krahn;Lynne Danis

  • A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium

    Nicole Soranzo;Nicole Soranzo;Tim D Spector;Massimo Mangino;Brigitte Kühnel

  • Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

    Cristian Pattaro;Alexander Teumer;Mathias Gorski;Audrey Y. Chu

  • Aptamer-based multiplexed proteomic technology for biomarker discovery

    Larry Gold;Deborah Ayers;Jennifer Bertino;Christopher Bock

  • Genetic variants influencing circulating lipid levels and risk of coronary artery disease.

    Dawn M. Waterworth;Sally L. Ricketts;Kijoung Song;Li Chen

  • Point-of-care genetic testing for personalisation of antiplatelet treatment (RAPID GENE): a prospective, randomised, proof-of-concept trial.

    Jason D Roberts;George A Wells;Michel R Le May;Marino Labinaz

  • Functional Analysis of the Chromosome 9p21.3 Coronary Artery Disease Risk Locus

    Olga Jarinova;Alexandre F.R. Stewart;Robert Roberts;George Wells

  • Rare Copy Number Variation Discovery and Cross-Disorder Comparisons Identify Risk Genes for ADHD

    Anath C. Lionel;Jennifer Crosbie;Nicole Barbosa;Tara Goodale

  • Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.

    M Dichgans;R Malik;I R König;J Rosand

  • A common allele on chromosome 9 associated with coronary heart disease

    Ruth McPherson;Alexander Pertsemlidis;Nihan Kavaslar;Alexandre Stewart

Frequent Co-Authors

Ruth McPherson
Ruth McPherson University of Ottawa
Nilesh J. Samani
Nilesh J. Samani University of Leicester
Robert Roberts
Robert Roberts University of Missouri
George A. Wells
George A. Wells University of Ottawa
Winfried März
Winfried März Medical University of Graz
Muredach P. Reilly
Muredach P. Reilly Columbia University
Christopher P. Nelson
Christopher P. Nelson University of Leicester
Jeanette Erdmann
Jeanette Erdmann University of Lübeck
Stanley L. Hazen
Stanley L. Hazen Cleveland Clinic Lerner College of Medicine
Sekar Kathiresan
Sekar Kathiresan Harvard University

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