Ivo P. Touw mostly deals with Immunology, Myeloid leukemia, Congenital Neutropenia, Leukemia and Granulocyte colony-stimulating factor receptor. The Immunology study combines topics in areas such as Haematopoiesis, Recombinant Granulocyte Colony-Stimulating Factor and IRF8. The subject of his Myeloid leukemia research is within the realm of Cancer research.
Ivo P. Touw works mostly in the field of Leukemia, limiting it down to topics relating to Progenitor cell and, in certain cases, Cell division, Cell culture and Cell surface receptor. Within one scientific family, Ivo P. Touw focuses on topics pertaining to Antigen under Monocyte, and may sometimes address concerns connected to Molecular biology. Ivo P. Touw has included themes like Cellular differentiation, Lymphocytic choriomeningitis, Signal transduction, Cell biology and Myelopoiesis in his Myeloid study.
His scientific interests lie mostly in Immunology, Cancer research, Haematopoiesis, Cell biology and Molecular biology. His Immunology research is multidisciplinary, incorporating elements of Congenital Neutropenia, Granulocyte colony-stimulating factor and In vitro. His work in Myeloid leukemia and Malignant transformation is related to Cancer research.
As a member of one scientific family, Ivo P. Touw mostly works in the field of Haematopoiesis, focusing on Granulocyte and, on occasion, Granulopoiesis. While the research belongs to areas of Molecular biology, Ivo P. Touw spends his time largely on the problem of Endocrinology, intersecting his research to questions surrounding Cell culture. His studies examine the connections between Signal transduction and genetics, as well as such issues in Receptor, with regards to Granulocyte colony-stimulating factor receptor and Ubiquitin.
The scientist’s investigation covers issues in Immunology, Cancer research, Congenital Neutropenia, Haematopoiesis and Leukemia. His Immunology research is multidisciplinary, relying on both Receptor, Juvenile myelomonocytic leukemia and Gene, Mutant. His Cancer research research is multidisciplinary, incorporating perspectives in DNA demethylation, CD5, Bone marrow and RUNX1.
The various areas that Ivo P. Touw examines in his Congenital Neutropenia study include Granulocyte colony-stimulating factor receptor, Chronic neutrophilic leukemia and Myeloid leukemia. His research integrates issues of Ubiquitin and Cytokine in his study of Granulocyte colony-stimulating factor receptor. His Haematopoiesis research incorporates themes from Progenitor cell, Hematology and Myeloid.
His primary areas of study are Immunology, Myeloid, Congenital Neutropenia, Leukemia and Cancer research. His study in the fields of Myeloid leukemia and Infiltration under the domain of Immunology overlaps with other disciplines such as Glomerulonephritis and Nephrotoxicity. The study of Congenital Neutropenia is intertwined with the study of Receptor in a number of ways.
The concepts of his Receptor study are interwoven with issues in Granulocyte colony-stimulating factor receptor, Cytokine, Ubiquitin and Mutation rate. Ivo P. Touw has included themes like breakpoint cluster region and B cell in his Leukemia study. His work focuses on many connections between Cancer research and other disciplines, such as Haematopoiesis, that overlap with his field of interest in CEBPA and Cellular differentiation.
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Mutations in the gene for the granulocyte colony-stimulating-factor receptor in patients with acute myeloid leukemia preceded by severe congenital neutropenia
Fan Dong;Russell K. Brynes;Nicola Tidow;Karl Welte.
The New England Journal of Medicine (1995)
The Jak-Stat pathway in normal and perturbed hematopoiesis
Alister C. Ward;Ivo Touw;Akihiko Yoshimura.
Mesenchymal Inflammation Drives Genotoxic Stress in Hematopoietic Stem Cells and Predicts Disease Evolution in Human Pre-leukemia.
Noemi A. Zambetti;Zhen Ping;Si Chen;Keane J.G. Kenswil.
Cell Stem Cell (2016)
Hematopoietic growth factors and their receptors in acute leukemia
B Lowenberg;IP Touw.
Distinct cytoplasmic regions of the human granulocyte colony-stimulating factor receptor involved in induction of proliferation and maturation
Fan Dong;C. van Buitenen;K. Pouwels;Lies Hoefsloot.
Molecular and Cellular Biology (1993)
Autonomous Proliferation of Leukemic Cells in Vitro as a Determinant of Prognosis in Adult Acute Myeloid Leukemia
B. Löwenberg;W. L. J. Van Putten;I. P. Touw;R. Delwel.
The New England Journal of Medicine (1993)
Identification of a nonsense mutation in the granulocyte-colony-stimulating factor receptor in severe congenital neutropenia
Fan Dong;Lies Hoefsloot;Anita Schelen;C.A. Broeders.
Proceedings of the National Academy of Sciences of the United States of America (1994)
Sustained Receptor Activation and Hyperproliferation in Response to Granulocyte Colony-stimulating Factor (G-CSF) in Mice with a Severe Congenital Neutropenia/Acute Myeloid Leukemia-derived Mutation in the G-CSF Receptor Gene
Mirjam H.A. Hermans;Claudia Antonissen;Alister C. Ward;Angelique E.M. Mayen.
Journal of Experimental Medicine (1999)
Interleukin-7 is a growth factor of precursor B and T acute lymphoblastic leukemia
I Touw;K Pouwels;T van Agthoven;R van Gurp.
Mutations in the granulocyte colony-stimulating factor receptor gene in patients with severe congenital neutropenia.
F. Dong;D. C. Dale;M. A. Bonilla;M. Freedman.
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