His scientific interests lie mostly in Signal transduction, Cell biology, Proto-oncogene tyrosine-protein kinase Src, LYN and Cancer research. In Signal transduction, he works on issues like Tyrosine, which are connected to Molecular biology. His work deals with themes such as Cell migration, Receptor, Biochemistry and Cancer, which intersect with Cell biology.
The subject of his Proto-oncogene tyrosine-protein kinase Src research is within the realm of Kinase. His research in LYN intersects with topics in Granulocyte colony-stimulating factor receptor, breakpoint cluster region and Myeloid leukemia. His study in Cancer research is interdisciplinary in nature, drawing from both Breast cancer, Breast disease, Doxorubicin and Tyrosine-kinase inhibitor.
His primary areas of study are Cell biology, Cancer research, LYN, Proto-oncogene tyrosine-protein kinase Src and Signal transduction. In his research, Endocytosis is intimately related to Cytoskeleton, which falls under the overarching field of Cell biology. His Cancer research study combines topics in areas such as Janus kinase, Cellular differentiation, Bone marrow and Tyrosine phosphorylation.
His LYN research incorporates elements of Molecular biology, Protein kinase B, Cell growth and Syk. Seth J. Corey interconnects Tyrosine kinase, Dasatinib and Receptor tyrosine kinase in the investigation of issues within Proto-oncogene tyrosine-protein kinase Src. The concepts of his Signal transduction study are interwoven with issues in Receptor, Tyrosine and Kinase.
The scientist’s investigation covers issues in Cell biology, Immunology, Pediatrics, Neutropenia and Internal medicine. His Cell biology research is multidisciplinary, relying on both Growth factor, Actin cytoskeleton and Dynamin. His Immunology study integrates concerns from other disciplines, such as Granulocyte colony-stimulating factor receptor, Congenital Neutropenia and Cancer research.
He studies Cancer research, namely Myeloid leukemia. His Neutropenia research is multidisciplinary, relying on both Granulocyte colony-stimulating factor and Granulocyte macrophage colony-stimulating factor. His LYN study improves the overall literature in Proto-oncogene tyrosine-protein kinase Src.
His main research concerns Neutropenia, Immunology, Pediatrics, Stem cell and Mutation. His Immunology study combines topics in areas such as Progenitor cell and Granulocyte colony-stimulating factor. The various areas that Seth J. Corey examines in his Pediatrics study include Novel agents, Drug development, Drug approval and MEDLINE.
His Stem cell research integrates issues from Filgrastim, Sargramostim, Adjuvant, Granulocyte macrophage colony-stimulating factor and Transplantation. Seth J. Corey has included themes like Neutrophil elastase, Receptor and Signal transduction in his Mutation study. His Myeloid leukemia study is concerned with the field of Cancer research as a whole.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
The t(5;17) variant of acute promyelocytic leukemia expresses a nucleophosmin-retinoic acid receptor fusion
Robert L. Redner;Elizabeth A. Rush;Susan Faas;William A. Rudert.
Myelodysplastic syndromes: the complexity of stem-cell diseases
Seth J. Corey;Mark D. Minden;Dwayne L. Barber;Hagop M Kantarjian.
Nature Reviews Cancer (2007)
A Bcr/Abl-independent, Lyn-dependent Form of Imatinib Mesylate (STI-571) Resistance Is Associated with Altered Expression of Bcl-2
Yun Dai;Mohamed Rahmani;Seth J. Corey;Paul Dent.
Journal of Biological Chemistry (2004)
Granulocyte macrophage-colony stimulating factor stimulates both association and activation of phosphoinositide 3OH-kinase and src-related tyrosine kinase(s) in human myeloid derived cells.
S. Corey;A. Eguinoa;K. Puyana-Theall;J.B. Bolen.
The EMBO Journal (1993)
G-CSF and GM-CSF in Neutropenia
Hrishikesh M. Mehta;Michael Malandra;Seth J. Corey;Seth J. Corey.
Journal of Immunology (2015)
Granulocyte colony-stimulating factor receptor signaling involves the formation of a three-component complex with Lyn and Syk protein-tyrosine kinases.
Seth J. Corey;Anne L. Burkhardt;Joseph B. Bolen;Robert L. Geahlen.
Proceedings of the National Academy of Sciences of the United States of America (1994)
Receptor stimulated accumulation of phosphatidylinositol (3,4,5)‐trisphosphate by G‐protein mediated pathways in human myeloid derived cells.
L Stephens;A Eguinoa;S Corey;T Jackson.
The EMBO Journal (1993)
Src-related protein tyrosine kinases in hematopoiesis
Seth J. Corey;Steven M. Anderson.
Dasatinib synergizes with doxorubicin to block growth, migration, and invasion of breast cancer cells.
C. S. Pichot;S. M. Hartig;L. Xia;C. Arvanitis.
British Journal of Cancer (2009)
G-CSF induced reactive oxygen species involves Lyn-PI3-kinase-Akt and contributes to myeloid cell growth
Quan Sheng Zhu;Ling Xia;Gordon B. Mills;Clifford A. Lowell.
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