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Molecular Biology

D-Index
100
Citations
32024
World Ranking
539
National Ranking
296

Research.com Recognitions

  • 1995 - Fellow of John Simon Guggenheim Memorial Foundation

Overview

Richard A. Firtel is affiliated with the University of California, San Diego in the United States. Their research focuses primarily on the intersections of biochemistry, genetics, molecular biology, medicine, and physics and astronomy. Within these broad fields, their work addresses specific subfields including cell biology, immunology and allergy, and atomic and molecular physics, and optics.

Their recent published work includes the paper titled "A Balance between Turning and Persistent Motion is Critical for Fast and Efficient 3-Dimensional Neutrophil Migration", which appeared in 2020 in the Biophysical Journal. This publication contributes to understanding the dynamics involved in cellular motion and immune response behavior.

Throughout their career, Richard A. Firtel has collaborated frequently with several researchers, such as:

  • Joshua François
  • Yi-Ting Yeh
  • Cindy Ayala
  • Juan C. del Álamo
  • Shu Chien

The main topics addressed in their research encompass:

  • Cellular Mechanics and Interactions
  • Cell Adhesion Molecules Research
  • Force Microscopy Techniques and Applications

Richard A. Firtel's work has been featured predominantly in the Biophysical Journal, reflecting their engagement with research relevant to biophysics. Their contributions span multiple scientific perspectives by integrating methodologies from various biological and physical sciences.

In recognition of their contributions, Richard A. Firtel was awarded the title of Fellow of the John Simon Guggenheim Memorial Foundation in 1995. This award acknowledges exceptional scholarship across disciplines.

Best Publications

  • Cell migration: integrating signals from front to back.

    Anne J. Ridley;Martin A. Schwartz;Keith Burridge;Richard A. Firtel

  • Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis

    Satoru Funamoto;Ruedi Meili;Susan Lee;Lisa Parry

  • Chemoattractant‐mediated transient activation and membrane localization of Akt/PKB is required for efficient chemotaxis to cAMP in Dictyostelium

    Ruedi Meili;Charlene Ellsworth;Susan Lee;T.B.K. Reddy

  • Localized Ras signaling at the leading edge regulates PI3K, cell polarity, and directional cell movement

    Atsuo T. Sasaki;Cheryl Chun;Kosuke Takeda;Richard A. Firtel

  • The regulation of cell motility and chemotaxis by phospholipid signaling

    Verena Kölsch;Pascale G. Charest;Richard A. Firtel

  • Signaling pathways controlling cell polarity and chemotaxis

    Chang Y Chung;Satoru Funamoto;Richard A Firtel

  • Induction and modulation of cell-type-specific gene expression in Dictyostelium.

    Mona C. Mehdy;David Ratner;Richard A. Firtel

  • Leading the way: directional sensing through phosphatidylinositol 3-kinase and other signaling pathways

    Sylvain Merlot;Richard A. Firtel

  • DNA-mediated transformation in Dictyostelium discoideum: regulated expression of an actin gene fusion.

    W Nellen;C Silan;R A Firtel

  • Role of Phosphatidylinositol 3′ Kinase and a Downstream Pleckstrin Homology Domain–Containing Protein in Controlling Chemotaxis inDictyostelium

    Satoru Funamoto;Kristina Milan;Ruedi Meili;Richard A. Firtel

  • Developmental regulation of a dictyostelium gene encoding a protein homologous to mammalian ras protein

    Christophe D. Reymond;Richard H. Gomer;Mona C. Mehdy;Richard A. Firtel

  • Chapter 4 Molecular Biology in Dictyostelium: Tools and Applications

    W. Nellen;S. Datta;C. Reymond;A. Sivertsen

  • Control of Cell Polarity and Chemotaxis by Akt/PKB and PI3 Kinase through the Regulation of PAKa

    Chang Y Chung;Gary Potikyan;Richard A Firtel

  • Phenocopy of discoidin I-minus mutants by antisense transformation in Dictyostelium

    Thomas E. Crowley;Wolfgang Nellen;Richard H. Gomer;Richard A. Firtel

  • Regulation and function of Gα protein subunits in Dictyostelium

    A. Kumagai;M. Pupillo;R. Gundersen;R. Miake-Lye

  • A small nuclear precursor of messenger RNA in the cellular slime mold Dictyostelium discoideum.

    Firtel Ra;Lodish Hf

  • G protein–independent Ras/PI3K/F-actin circuit regulates basic cell motility

    Atsuo T. Sasaki;Chris Janetopoulos;Chris Janetopoulos;Susan Lee;Pascale G. Charest

  • Receptor-mediated Regulation of PI3Ks Confines PI(3,4,5)P3 to the Leading Edge of Chemotaxing Cells

    Yi Elaine Huang;Miho Iijima;Carole A. Parent;Satoru Funamoto

  • A secreted factor and cyclic AMP jointly regulate cell-type-specific gene expression in Dictyostelium discoideum.

    Mona Mehdy;R. A. Firtel

  • Establishment of a transient expression system for Dictyostelium discoideum

    Peter K. Howard;Kevin G. Ahern;Richard A. Firtel

Frequent Co-Authors

Juan C. Lasheras
Juan C. Lasheras University of California, San Diego
Peter N. Devreotes
Peter N. Devreotes Johns Hopkins University
Richard H. Gomer
Richard H. Gomer Texas A&M University
Atsuo T. Sasaki
Atsuo T. Sasaki University of Cincinnati
Alan R. Kimmel
Alan R. Kimmel National Institutes of Health
William F. Loomis
William F. Loomis University of California, San Diego
Zhouxin Shen
Zhouxin Shen University of California, San Diego
Steven P. Briggs
Steven P. Briggs University of California, San Diego
Tony Hunter
Tony Hunter Salk Institute for Biological Studies

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