D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Molecular Biology D-index 97 Citations 30,429 305 World Ranking 336 National Ranking 198

Research.com Recognitions

Awards & Achievements

1995 - Fellow of John Simon Guggenheim Memorial Foundation

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Enzyme

Richard A. Firtel mainly focuses on Cell biology, Dictyostelium, Chemotaxis, Gene and Molecular biology. His research in Cell biology intersects with topics in Cell migration, Cytoskeleton and Cell polarity. His Cell migration research includes themes of GTP-binding protein regulators, Guanine nucleotide exchange factor and Actin cytoskeleton.

His Dictyostelium study incorporates themes from Cell aggregation, Cell, Cell type and Dictyostelium discoideum. Richard A. Firtel has researched Chemotaxis in several fields, including Protein kinase B, PI3K/AKT/mTOR pathway, Signal transduction and Kinase. His Molecular biology study combines topics in areas such as Plasmid, Tyrosine, G protein-coupled receptor and Recombinant DNA.

His most cited work include:

  • Cell migration: integrating signals from front to back. (3919 citations)
  • Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis (668 citations)
  • Chemoattractant‐mediated transient activation and membrane localization of Akt/PKB is required for efficient chemotaxis to cAMP in Dictyostelium (404 citations)

What are the main themes of his work throughout his whole career to date?

Richard A. Firtel mostly deals with Cell biology, Dictyostelium, Dictyostelium discoideum, Molecular biology and Gene. His Cell biology research integrates issues from Morphogenesis, Chemotaxis and Cytoskeleton. Richard A. Firtel has included themes like Protein kinase B, Actin cytoskeleton, Pseudopodia, PI3K/AKT/mTOR pathway and Cell polarity in his Chemotaxis study.

The Dictyostelium study combines topics in areas such as Cell, Gene expression, Cellular differentiation, Motility and Transcription. His Dictyostelium discoideum study integrates concerns from other disciplines, such as RNA, Regulation of gene expression, Slime mold and Messenger RNA. The study incorporates disciplines such as Plasmid, DNA, Recombinant DNA, Ribosomal RNA and Heterotrimeric G protein in addition to Molecular biology.

He most often published in these fields:

  • Cell biology (52.12%)
  • Dictyostelium (51.14%)
  • Dictyostelium discoideum (32.57%)

What were the highlights of his more recent work (between 2010-2020)?

  • Cell biology (52.12%)
  • Motility (10.42%)
  • Dictyostelium (51.14%)

In recent papers he was focusing on the following fields of study:

The scientist’s investigation covers issues in Cell biology, Motility, Dictyostelium, Chemotaxis and Cell migration. His research integrates issues of Spindle apparatus, Dictyostelium discoideum and Cleavage furrow in his study of Cell biology. His Motility research is multidisciplinary, relying on both Cell, Cell adhesion and Cell culture.

His Dictyostelium study is concerned with the field of Gene as a whole. Richard A. Firtel has included themes like Signal transduction, G protein-coupled receptor, Pseudopodia, Effector and Cell polarity in his Chemotaxis study. His Cell migration research includes themes of WAVE complex, Biophysics and Cytoskeleton.

Between 2010 and 2020, his most popular works were:

  • Incoherent Feedforward Control Governs Adaptation of Activated Ras in a Eukaryotic Chemotaxis Pathway (124 citations)
  • Three-dimensional quantification of cellular traction forces and mechanosensing of thin substrata by fourier traction force microscopy. (77 citations)
  • Activated Membrane Patches Guide Chemotactic Cell Motility (66 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Enzyme

His primary scientific interests are in Cell biology, Chemotaxis, Motility, Actin and Dictyostelium. Richard A. Firtel works in the field of Cell biology, namely Myosin. His research in Chemotaxis intersects with topics in Pseudopodia, Signal transduction and Actin cytoskeleton.

In his study, which falls under the umbrella issue of Motility, Cell adhesion, Single-cell analysis and Membrane is strongly linked to Dictyostelium discoideum. His work deals with themes such as Mechanotransduction, Asymmetric cell division, Cleavage furrow and INCENP, which intersect with Actin. His study looks at the relationship between Dictyostelium and topics such as Cell migration, which overlap with Cytoplasm and Cell shape.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Cell migration: integrating signals from front to back.

Anne J. Ridley;Martin A. Schwartz;Keith Burridge;Richard A. Firtel.
Science (2003)

5723 Citations

Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis

Satoru Funamoto;Ruedi Meili;Susan Lee;Lisa Parry.
Cell (2002)

919 Citations

Chemoattractant‐mediated transient activation and membrane localization of Akt/PKB is required for efficient chemotaxis to cAMP in Dictyostelium

Ruedi Meili;Charlene Ellsworth;Susan Lee;T.B.K. Reddy.
The EMBO Journal (1999)

545 Citations

Localized Ras signaling at the leading edge regulates PI3K, cell polarity, and directional cell movement

Atsuo T. Sasaki;Cheryl Chun;Kosuke Takeda;Richard A. Firtel.
Journal of Cell Biology (2004)

425 Citations

Signaling pathways controlling cell polarity and chemotaxis

Chang Y Chung;Satoru Funamoto;Richard A Firtel.
Trends in Biochemical Sciences (2001)

422 Citations

The regulation of cell motility and chemotaxis by phospholipid signaling

Verena Kölsch;Pascale G. Charest;Richard A. Firtel.
Journal of Cell Science (2008)

412 Citations

Induction and modulation of cell-type-specific gene expression in Dictyostelium.

Mona C. Mehdy;David Ratner;Richard A. Firtel.
Cell (1983)

388 Citations

Leading the way: directional sensing through phosphatidylinositol 3-kinase and other signaling pathways

Sylvain Merlot;Richard A. Firtel.
Journal of Cell Science (2003)

388 Citations

DNA-mediated transformation in Dictyostelium discoideum: regulated expression of an actin gene fusion.

W Nellen;C Silan;R A Firtel.
Molecular and Cellular Biology (1984)

370 Citations

Role of Phosphatidylinositol 3′ Kinase and a Downstream Pleckstrin Homology Domain–Containing Protein in Controlling Chemotaxis inDictyostelium

Satoru Funamoto;Kristina Milan;Ruedi Meili;Richard A. Firtel.
Journal of Cell Biology (2001)

303 Citations

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