D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Molecular Biology D-index 61 Citations 12,905 125 World Ranking 1267 National Ranking 652

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Amino acid

Alan R. Kimmel mainly focuses on Perilipin, Lipid droplet, Biochemistry, Perilipin-1 and Lipid metabolism. His research integrates issues of Human genome, Conserved sequence, Gene, Protein family and Perilipin 2 in his study of Perilipin. The study incorporates disciplines such as Genetics and Computational biology in addition to Lipid droplet.

His work on Protein kinase A, Phosphorylation and Receptor as part of general Biochemistry study is frequently linked to Muscarinic acetylcholine receptor M5 and Follicle-stimulating hormone receptor, therefore connecting diverse disciplines of science. His research in Perilipin-1 intersects with topics in Cell fractionation, Peptide sequence, Gene isoform and Cell biology. Alan R. Kimmel interconnects Cell fate determination and Dictyostelium in the investigation of issues within Cell biology.

His most cited work include:

  • Perilipin ablation results in a lean mouse with aberrant adipocyte lipolysis, enhanced leptin production, and resistance to diet-induced obesity (614 citations)
  • Perilipin A is essential for the translocation of hormone-sensitive lipase during lipolytic activation (431 citations)
  • A chemoattractant receptor controls development in Dictyostelium discoideum. (422 citations)

What are the main themes of his work throughout his whole career to date?

Alan R. Kimmel mainly investigates Cell biology, Dictyostelium, Biochemistry, Perilipin and Lipid droplet. In his study, which falls under the umbrella issue of Cell biology, Cell, Cell migration, Morphogen, PI3K/AKT/mTOR pathway and Phagocytosis is strongly linked to Chemotaxis. His Dictyostelium research includes elements of Dictyostelium discoideum, Gene expression, Cellular differentiation and Multicellular organism.

His Dictyostelium discoideum research focuses on subjects like G protein, which are linked to Cell surface receptor. His Perilipin research is mostly focused on the topic Perilipin-1. His biological study spans a wide range of topics, including Fatty acid, Lipid metabolism, Endocrinology and Perilipin 2.

He most often published in these fields:

  • Cell biology (47.69%)
  • Dictyostelium (43.08%)
  • Biochemistry (33.08%)

What were the highlights of his more recent work (between 2015-2021)?

  • Cell biology (47.69%)
  • Dictyostelium (43.08%)
  • Lipid droplet (23.85%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Cell biology, Dictyostelium, Lipid droplet, Chemotaxis and Perilipin. Alan R. Kimmel specializes in Cell biology, namely Intracellular. Alan R. Kimmel has researched Dictyostelium in several fields, including Cell aggregation, Signal transduction and Cell growth.

His work carried out in the field of Lipid droplet brings together such families of science as Beta oxidation and Endocrinology, Lipid metabolism. His Chemotaxis research is multidisciplinary, incorporating perspectives in Cell migration, Dictyostelium discoideum, Phagocytosis and MAPK/ERK pathway. In his study, Thermogenin, Adipose tissue, White adipose tissue and Transcription is inextricably linked to Regulation of gene expression, which falls within the broad field of Perilipin.

Between 2015 and 2021, his most popular works were:

  • The Perilipins: Major Cytosolic Lipid Droplet–Associated Proteins and Their Roles in Cellular Lipid Storage, Mobilization, and Systemic Homeostasis* (117 citations)
  • Perilipin 5 is protective in the ischemic heart (19 citations)
  • Loss of perilipin 2 in cultured myotubes enhances lipolysis and redirects the metabolic energy balance from glucose oxidation towards fatty acid oxidation. (17 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Amino acid

His primary scientific interests are in Lipid droplet, Perilipin, Cell biology, Regulation of gene expression and Biochemistry. He combines subjects such as Beta oxidation and Glucose uptake with his study of Lipid droplet. His research links Lipid metabolism with Perilipin.

His Cell biology study integrates concerns from other disciplines, such as Adipose tissue, Thermogenin, White adipose tissue and Cell. The various areas that Alan R. Kimmel examines in his Regulation of gene expression study include Scaffold protein, Perilipin-1, Phosphorylation, Organelle and Energy homeostasis. His Biochemistry study incorporates themes from Randle cycle and Skeletal muscle.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Perilipin ablation results in a lean mouse with aberrant adipocyte lipolysis, enhanced leptin production, and resistance to diet-induced obesity

J. T. Tansey;C. Sztalryd;J. Gruia-Gray;D. L. Roush.
Proceedings of the National Academy of Sciences of the United States of America (2001)

867 Citations

Perilipin A is essential for the translocation of hormone-sensitive lipase during lipolytic activation

Carole Sztalryd;Guoheng Xu;Heidi Dorward;John T. Tansey.
Journal of Cell Biology (2003)

685 Citations

Perilipin A Increases Triacylglycerol Storage by Decreasing the Rate of Triacylglycerol Hydrolysis

Dawn L. Brasaemle;Dawn L. Brasaemle;Boris Rubin;Boris Rubin;Ingrid A. Harten;Jasmine Gruia-Gray.
Journal of Biological Chemistry (2000)

583 Citations

A chemoattractant receptor controls development in Dictyostelium discoideum.

Peter S. Klein;Tzeli J. Sun;Charles L. Saxe;Alan R. Kimmel.
Science (1988)

567 Citations

Adoption of PERILIPIN as a unifying nomenclature for the mammalian PAT-family of intracellular lipid storage droplet proteins.

Alan R. Kimmel;Dawn L. Brasaemle;Monica McAndrews-Hill;Carole Sztalryd.
Journal of Lipid Research (2010)

527 Citations

Perilipins, ADRP, and other proteins that associate with intracellular neutral lipid droplets in animal cells.

Constantine Londos;Dawn L. Brasaemle;Charles J. Schultz;Jere P. Segrest.
Seminars in Cell & Developmental Biology (1999)

522 Citations

Functional conservation for lipid storage droplet association among Perilipin, ADRP, and TIP47 (PAT)-related proteins in mammals, Drosophila, and Dictyostelium.

Shinji Miura;Jai-Wei Gan;Joseph Brzostowski;Michael J. Parisi.
Journal of Biological Chemistry (2002)

422 Citations

GSK3, a master switch regulating cell-fate specification and tumorigenesis.

Leung Kim;Alan R Kimmel.
Current Opinion in Genetics & Development (2000)

342 Citations

Role of PAT proteins in lipid metabolism

C. Londos;C. Sztalryd;J.T. Tansey;A.R. Kimmel.
Biochimie (2005)

340 Citations

On the control of lipolysis in adipocytes.

Constantine Londos;Dawn L. Brasaemle;Charles J. Schultz;Diane C. Adler-Wailes.
Annals of the New York Academy of Sciences (1999)

335 Citations

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