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Microbiology

D-Index
42
Citations
7317
World Ranking
5342
National Ranking
11

Overview

Guillermo Garcia-Effron is affiliated with the National University of the Littoral in Argentina. Their research primarily focuses on medicine, with 76 publications in this field. Within medicine, their work is concentrated on the subfields of infectious diseases, epidemiology, cell biology, molecular biology, and pharmacology.

The scientist's main topics of investigation include antifungal resistance and susceptibility, fungal infections and studies, plant pathogens and fungal diseases, nail diseases and treatments, fungal biology and applications, mycotoxins in agriculture and food, and yeasts and rust fungi studies.

Guillermo Garcia-Effron has contributed to several recent publications, including:

  • Global guideline for the diagnosis and management of rare yeast infections: an initiative of the ECMM in cooperation with ISHAM and ASM (2021, The Lancet Infectious Diseases)
  • Rezafungin-Mechanisms of Action, Susceptibility and Resistance: Similarities and Differences with the Other Echinocandins (2020, Journal of Fungi)
  • Infections due to Rare Cryptococcus Species. A Literature Review (2021, Journal of Fungi)
  • Molecular Markers of Antifungal Resistance: Potential Uses in Routine Practice and Future Perspectives (2021, Journal of Fungi)
  • Head-to-head comparison of CLSI, EUCAST, Etest and VITEK®2 results for Candida auris susceptibility testing (2022, International Journal of Antimicrobial Agents)

The venues in which Guillermo Garcia-Effron frequently publishes include Medical Mycology, Journal of Fungi, Mycoses, Antimicrobial Agents and Chemotherapy, and Revista Argentina de Microbiología.

Frequent collaborators with whom they have co-authored multiple works include Soledad Gamarra, Gustavo Giusiano, Daiana Macedo, Natalia Sasoni, and Matías S. Cabeza.

Best Publications

  • A New Aspergillus fumigatus Resistance Mechanism Conferring In Vitro Cross-Resistance to Azole Antifungals Involves a Combination of cyp51A Alterations

    E. Mellado;G. Garcia-Effron;L. Alcázar-Fuoli;W. J. G. Melchers

  • A naturally occurring proline-to-alanine amino acid change in Fks1p in Candida parapsilosis, Candida orthopsilosis, and Candida metapsilosis accounts for reduced echinocandin susceptibility.

    Guillermo Garcia-Effron;Santosh K. Katiyar;Steven Park;Thomas D. Edlind

  • Effect of Candida glabrata FKS1 and FKS2 Mutations on Echinocandin Sensitivity and Kinetics of 1,3-β-d-Glucan Synthase: Implication for the Existing Susceptibility Breakpoint

    Guillermo Garcia-Effron;Samuel Lee;Steven Park;John D. Cleary

  • Correlating echinocandin MIC and kinetic inhibition of fks1 mutant glucan synthases for Candida albicans: implications for interpretive breakpoints.

    Guillermo Garcia-Effron;Steven Park;David S. Perlin

  • Substitutions at Methionine 220 in the 14α-Sterol Demethylase (Cyp51A) of Aspergillus fumigatus Are Responsible for Resistance In Vitro to Azole Antifungal Drugs

    Emilia Mellado;Guillermo Garcia-Effron;Laura Alcazar-Fuoli;Manuel Cuenca-Estrella

  • Requirement for ergosterol in V-ATPase function underlies antifungal activity of azole drugs.

    Yong Qiang Zhang;Soledad Gamarra;Guillermo Garcia-Effron;Steven Park

  • Breakthrough Invasive Candidiasis in Patients on Micafungin

    Christopher D. Pfeiffer;Guillermo Garcia-Effron;Aimee K. Zaas;John R. Perfect

  • Echinocandin susceptibility testing of Candida species: comparison of EUCAST EDef 7.1, CLSI M27-A3, Etest, disk diffusion, and agar dilution methods with RPMI and isosensitest media

    Maiken Cavling Arendrup;Guillermo Garcia-Effron;Cornelia Lass-Flörl;Alicia Gomez Lopez

  • Ergosterol biosynthesis pathway in Aspergillus fumigatus.

    Laura Alcazar-Fuoli;Emilia Mellado;Guillermo Garcia-Effron;Jordi F. Lopez

  • A Ser678Pro Substitution in Fks1p Confers Resistance to Echinocandin Drugs in Aspergillus fumigatus

    Eleusa Maria F. Rocha;Guillermo Garcia-Effron;Steven Park;David S. Perlin

  • Global guideline for the diagnosis and management of rare yeast infections: an initiative of the ECMM in cooperation with ISHAM and ASM

    Sharon C-A Chen;John Perfect;Arnaldo L Colombo;Oliver A Cornely

  • Caspofungin-Resistant Candida tropicalis Strains Causing Breakthrough Fungemia in Patients at High Risk for Hematologic Malignancies

    Guillermo Garcia-Effron;Dimitrios P. Kontoyiannis;Russell E. Lewis;David S. Perlin

  • Fitness and virulence costs of Candida albicans FKS1 hot spot mutations associated with echinocandin resistance

    Ronen Ben-Ami;Guillermo Garcia-Effron;Russell E. Lewis;Russell E. Lewis;Soledad Gamarra

  • Targeted Gene Disruption of the 14-α Sterol Demethylase (cyp51A) in Aspergillus fumigatus and Its Role in Azole Drug Susceptibility

    Emilia Mellado;Guillermo Garcia-Effron;Maria Jose Buitrago;Laura Alcazar-Fuoli

  • Reduced Candida glabrata susceptibility secondary to an FKS1 mutation developed during candidemia treatment

    John D. Cleary;Guillermo Garcia-Effron;Stanley W. Chapman;David S. Perlin

  • Acquired Echinocandin Resistance in a Candida krusei Isolate Due to Modification of Glucan Synthase

    Jennifer Nielsen Kahn;Guillermo Garcia-Effron;Ming Jo Hsu;Steven Park

  • Serum Differentially Alters the Antifungal Properties of Echinocandin Drugs

    Padmaja Paderu;Guillermo Garcia-Effron;Sergey Balashov;Guillaume Delmas

  • Rapid Detection of Triazole Antifungal Resistance in Aspergillus fumigatus

    Guillermo Garcia-Effron;Amanda Dilger;Laura Alcazar-Fuoli;Steven Park

  • Novel FKS Mutations Associated with Echinocandin Resistance in Candida Species

    Guillermo Garcia-Effron;Daniel Joseph Chua;Jon Rupert Tomada;Joseph DiPersio

  • Breakthrough Aspergillus fumigatus and Candida albicans Double Infection during Caspofungin Treatment: Laboratory Characteristics and Implication for Susceptibility Testing

    Maiken Cavling Arendrup;Guillermo Garcia-Effron;Walter Buzina;Klaus Leth Mortensen

  • Establishing In Vitro-In Vivo Correlations for Aspergillus fumigatus: the Challenge of Azoles versus Echinocandins

    Maiken Cavling Arendrup;Susanne Perkhofer;Susan J. Howard;Guillermo Garcia-Effron

Frequent Co-Authors

David S. Perlin
David S. Perlin Rutgers, The State University of New Jersey
Manuel Cuenca-Estrella
Manuel Cuenca-Estrella Instituto de Salud Carlos III
Emilia Mellado
Emilia Mellado Instituto de Salud Carlos III
Juan L. Rodriguez-Tudela
Juan L. Rodriguez-Tudela Global Action for Fungal Infections (GAFFI)
Steven Park
Steven Park Rutgers, The State University of New Jersey
Maiken Cavling Arendrup
Maiken Cavling Arendrup Statens Serum Institut
John D. Turnidge
John D. Turnidge University of Adelaide
Ana Espinel-Ingroff
Ana Espinel-Ingroff Virginia Commonwealth University Medical Center
Teresa Peláez
Teresa Peláez Hospital General Universitario Gregorio Marañón
Jesús Guinea
Jesús Guinea Hospital General Universitario Gregorio Marañón

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