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Biology and Biochemistry

D-Index
57
Citations
12062
World Ranking
13808
National Ranking
5841

Overview

Timothy A. Donlon is affiliated with the University of Hawaii at Manoa in the United States. Their research primarily focuses on the intersection of biochemistry, genetics, and molecular biology with medicine, reflecting a strong interdisciplinary approach in their scientific work.

Donlon has published extensively in subfields including molecular biology, aging, and physiology, with contributions also touching on rheumatology as well as pediatrics, perinatology, and child health. Their research portfolio encompasses key topics related to genetics, aging, and longevity in model organisms, as well as FOXO transcription factor regulation. Additional topics explored include adipose tissue and metabolism, GDF15 and related biomarkers, dietary effects on health, birth, development and health, and dementia and cognitive impairment research.

The scientist's frequent publication venues highlight their active involvement in aging and gerontology research. Notable journals with multiple publications include Aging, Journal of Hypertension, The Journals of Gerontology Series A, GeroScience, and Innovation in Aging.

Timothy A. Donlon's collaborative work features several frequent coauthors known within the field. These include Bradley J. Willcox, Brian J. Morris, Randi Chen, Richard Allsopp, and Kamal Masaki, indicating a network of partnerships influencing research in longevity and related biomedical sciences.

Recent representative papers authored or coauthored by Donlon span important aspects of FOXO transcription factors and longevity research. Significant examples include:

  • "FOXO transcription factors as therapeutic targets in human diseases" (2022, Trends in Pharmacological Sciences)
  • "Pharmaceutical and nutraceutical activation of FOXO3 for healthy longevity" (2022, Ageing Research Reviews)
  • "FOXO3 longevity genotype mitigates the increased mortality risk in men with a cardiometabolic disease" (2020, Aging)
  • "Novel Functional, Health, and Genetic Determinants of Cognitive Terminal Decline: Kuakini Honolulu Heart Program/Honolulu-Asia Aging Study" (2021, The Journals of Gerontology Series A)
  • "Vascular endothelial growth factor receptor 1 gene (FLT1) longevity variant increases lifespan by reducing mortality risk posed by hypertension" (2023, Aging)

Best Publications

  • FOXO3A genotype is strongly associated with human longevity

    Bradley J. Willcox;Timothy A. Donlon;Qimei He;Randi Chen

  • Identification of cDNA clones for the human microtubule-associated protein tau and chromosomal localization of the genes for tau and microtubule-associated protein 2

    Rachael L. Neve;Rachael L. Neve;Peter C Harris;Peter C Harris;Kenneth S. Kosik;David M. Kurnit;David M. Kurnit

  • Detection of bcr-abl fusion in chronic myelogeneous leukemia by in situ hybridization

    D. C. Tkachuk;C. A. Westbrook;Michael Andreeff;T. A. Donlon

  • Human von Willebrand factor (vWF): isolation of complementary DNA (cDNA) clones and chromosomal localization

    David Ginsburg;David Ginsburg;Robert I. Handin;Robert I. Handin;David T. Bonthron;Timothy A. Donlon;Timothy A. Donlon

  • Association of the hOGG1 Ser326Cys polymorphism with lung cancer risk.

    Loïc Le Marchand;Timothy Donlon;Annette Lum-Jones;Ann Seifried

  • FOXO3: A Major Gene for Human Longevity--A Mini-Review.

    Brian J. Morris;Donald Craig Willcox;Timothy A. Donlon;Bradley J. Willcox

  • Treatment of myelodysplastic syndromes with recombinant human granulocyte colony-stimulating factor. A phase I-II trial.

    Robert S. Negrin;Douglas H. Haeuber;Arnon Nagler;Lynne C. Olds

  • Small nuclear ribonucleoprotein polypeptide N (SNRPN), an expressed gene in the Prader–Willi syndrome critical region

    Tayfun Özçelik;Stuart Leff;Wendy Robinson;Tim Donlon

  • Maintenance treatment of patients with myelodysplastic syndromes using recombinant human granulocyte colony-stimulating factor.

    Robert S. Negrin;Douglas H. Haeuber;Arnon Nagler;Yukio Kobayashi

  • Performance-based measures of physical function for high-function populations.

    J. David Curb;Clementina D. Ceria‐Ulep;Beatriz L. Rodriguez;John Grove

  • B-vitamin intake, metabolic genes, and colorectal cancer risk (United States).

    Loic Le Marchand;Timothy Donlon;Jean H. Hankin;Laurence N. Kolonel

  • Combined effects of well-done red meat, smoking, and rapid N-acetyltransferase 2 and CYP1A2 phenotypes in increasing colorectal cancer risk.

    Loïc Le Marchand;Jean H. Hankin;Lynne R. Wilkens;Lisa M. Pierce

  • Clinical heterogeneity associated with deletions in the long arm of chromosome 15: report of 3 new cases and their possible genetic significance.

    L C Kaplan;R Wharton;E Elias;F Mandell

  • The gene for enhancer binding proteins E12/E47 lies at the t(1;19) breakpoint in acute leukemias.

    Julia D. Mellentin;Cornelis Murre;Timothy A. Donlon;Patrick S. McCaw

  • Case-Control Study of Ovarian Cancer and Polymorphisms in Genes Involved in Catecholestrogen Formation and Metabolism

    Marc T. Goodman;Katharine McDuffie;Laurence N. Kolonel;Keith Terada

  • Isolation of molecular probes associated with the chromosome 15 instability in the Prader-Willi syndrome.

    T A Donlon;M Lalande;A Wyman;G Bruns

  • Well-done red meat, metabolic phenotypes and colorectal cancer in Hawaii.

    Loı̈c Le Marchand;Jean H Hankin;Lisa M Pierce;Rashmi Sinha

  • Estrogen Metabolism–Related Genes and Breast Cancer Risk: The Multiethnic Cohort Study

    Loïc Le Marchand;Timothy Donlon;Laurence N. Kolonel;Brian E. Henderson

  • Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations.

    Marc A. Coram;Qing Duan;Thomas J. Hoffmann;Timothy Thornton

  • Fine mapping of the Autosomal Dominant Split Hand/Split Foot Locus on Chromosome 7, Band q21.3-q22.1

    Stephen W. Scherer;Parvoneh Poorkaj;Todd Allen;Julia Kim

Frequent Co-Authors

Kamal Masaki
Kamal Masaki University of Hawaii at Manoa
Samuel A. Latt
Samuel A. Latt Boston Children's Hospital
Beatriz L. Rodriguez
Beatriz L. Rodriguez University of Hawaii at Manoa
Lynne R. Wilkens
Lynne R. Wilkens University of Hawaii at Manoa
Loic Le Marchand
Loic Le Marchand University of Hawaii at Manoa
Marc Lalande
Marc Lalande University of Connecticut Health Center
Peter L. Greenberg
Peter L. Greenberg Stanford University
Robert S. Negrin
Robert S. Negrin Stanford University
Michael L. Cleary
Michael L. Cleary Stanford University
Leonard W. Poon
Leonard W. Poon University of Georgia

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