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David Lillicrap

David Lillicrap

D-Index & Metrics

Biology and Biochemistry

D-Index
72
Citations
17516
World Ranking
6342
National Ranking
230

Research.com Recognitions

  • 2013 - Fellow of the Royal Society of Canada Academy of Science

Overview

David Lillicrap is affiliated with Queen's University in Canada. Their research primarily falls within the field of Medicine, with a strong focus on Hematology. Additional subfields include Genetics, Molecular Biology, Infectious Diseases, and Internal Medicine.

The scientist's work covers key topics such as Platelet Disorders and Treatments, Hemophilia Treatment and Research, Blood Coagulation and Thrombosis Mechanisms, Venous Thromboembolism Diagnosis and Management, Blood groups and transfusion, Virus-based gene therapy research, and Cancer-related gene regulation.

Among recent publications, notable papers include:

  • "Effectiveness of therapeutic heparin versus prophylactic heparin on death, mechanical ventilation, or intensive care unit admission in moderately ill patients with covid-19 admitted to hospital: RAPID randomised clinical trial" (2021, BMJ)
  • "Disseminated intravascular coagulation in patients with 2019-nCoV pneumonia" (2020, Journal of Thrombosis and Haemostasis)
  • "Tolerating Factor VIII: Recent Progress" (2020, Frontiers in Immunology)
  • "Hemophilia Gene Therapy: Approaching the First Licensed Product" (2021, HemaSphere)
  • "Assembly of alternative prothrombinase by extracellular histones initiates and disseminates intravascular coagulation" (2020, Blood)

Frequent co-authors collaborating with David Lillicrap include James H. Morrissey, Paul Batty, Laura L. Swystun, Manuel Carção, and Orla Rawley.

Their research has been published extensively in several journals, with the most frequent venues being the Journal of Thrombosis and Haemostasis, Research and Practice in Thrombosis and Haemostasis, Blood, Haemophilia, and Blood Advances.

David Lillicrap was awarded the title of Fellow of the Royal Society of Canada in 2013, recognizing involvement in the Academy of Science.

Best Publications

  • Update on the pathophysiology and classification of von Willebrand disease: a report of the Subcommittee on von Willebrand Factor

    J E Sadler;U Budde;J C J Eikenboom;E J Favaloro

  • ISTH/SSC bleeding assessment tool: a standardized questionnaire and a proposal for a new bleeding score for inherited bleeding disorders

    F. Rodeghiero;A. Tosetto;T. Abshire;D. M. Arnold

  • Factor VIII gene inversions in severe hemophilia A: results of an international consortium study

    S. E. Antonarakis;J. P. Rossiter;M. Young;J. Horst

  • The mutational spectrum of type 1 von Willebrand disease: results from a Canadian cohort study

    Paula D. James;Colleen Notley;Carol Hegadorn;Jayne Leggo

  • Disseminated intravascular coagulation in patients with 2019-nCoV pneumonia.

    David Lillicrap

  • Tailored prophylaxis in severe hemophilia A: interim results from the first 5 years of the Canadian Hemophilia Primary Prophylaxis Study.

    B. M. Feldman;M. Pai;G. E. Rivard;S. Israels

  • Multiyear therapeutic benefit of AAV serotypes 2, 6, and 8 delivering factor VIII to hemophilia A mice and dogs.

    Haiyan Jiang;David Lillicrap;Susannah Patarroyo-White;Tongyao Liu

  • Intensive exposure to factor VIII is a risk factor for inhibitor development in mild hemophilia A.

    A. Sharathkumar;D. Lillicrap;V. S. Blanchette;M. Kern

  • Adenovirus-induced thrombocytopenia : the role of von willebrand factor and p-selectin in mediating accelerated platelet clearance

    Maha Othman;Andrea Labelle;Ian Mazzetti;Hisham S. Elbatarny

  • Generation and validation of the Condensed MCMDM-1VWD Bleeding Questionnaire for von Willebrand disease.

    M. Bowman;G. Mundell;J. Grabell;W. M. Hopman

  • von Willebrand disease: advances in pathogenetic understanding, diagnosis, and therapy

    David Lillicrap

  • The prevalence of symptomatic von Willebrand disease in primary care practice

    M. Bowman;W. M. Hopman;D. Rapson;D. Lillicrap

  • Eradication of neutralizing antibodies to factor VIII in canine hemophilia A after liver gene therapy

    Jonathan D. Finn;Margareth C. Ozelo;Denise E. Sabatino;Helen W. G. Franck

  • Life in the shadow of a dominant partner: the FVIII-VWF association and its clinical implications for hemophilia A

    Steven W. Pipe;Robert R. Montgomery;Kathleen P. Pratt;Peter J. Lenting

  • Therapeutic factor VIII levels and negligible toxicity in mouse and dog models of hemophilia A following gene therapy with high-capacity adenoviral vectors

    Marinee K L Chuah;Gudrun Schiedner;Lieven Thorrez;Brian Brown

  • von Willebrand disease in a pediatric-based population--comparison of type 1 diagnostic criteria and use of the PFA-100 and a von Willebrand factor/collagen-binding assay.

    J.A. Dean;V. S. Blanchette;M. D. Carcao;A. M. Stain

  • Theories of blood coagulation.

    James P. Riddel;Bradley E. Aouizerat;Christine Miaskowski;David P. Lillicrap

  • Effect of the Factor V Leiden Mutation on the Clinical Expression of Severe Hemophilia A

    D. H. Lee;I. R. Walker;J. Teitel;M.-C. Poon

  • Variation at the von Willebrand factor (vWF) gene locus is associated with plasma vWF :Ag levels : Identification of three novel single nucleotide polymorphisms in the vWF gene promoter

    Angela M. Keightley;Y. Miu Lam;Jolene N. Brady;Cherie L. Cameron

  • Systemic delivery of an adenoviral vector encoding canine factor VIII results in short-term phenotypic correction, inhibitor development, and biphasic liver toxicity in hemophilia A dogs

    Angela M. Gallo-Penn;Pamela S. Shirley;Julie L. Andrews;Shawn Tinlin

Frequent Co-Authors

Brian D. Brown
Brian D. Brown Icahn School of Medicine at Mount Sinai
Robert R. Montgomery
Robert R. Montgomery Medical College of Wisconsin
James H. Morrissey
James H. Morrissey University of Michigan–Ann Arbor
Thierry VandenDriessche
Thierry VandenDriessche Vrije Universiteit Brussel
Bradley N. White
Bradley N. White Trent University
Stefan Kochanek
Stefan Kochanek University of Ulm
Flora Peyvandi
Flora Peyvandi University of Milan
Emmanuel J. Favaloro
Emmanuel J. Favaloro Westmead Hospital
Marinee Chuah
Marinee Chuah KU Leuven
Erik Berntorp
Erik Berntorp Lund University

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