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Marinee Chuah

Marinee Chuah

D-Index & Metrics

Biology and Biochemistry

D-Index
58
Citations
9356
World Ranking
13435
National Ranking
242

Overview

Marinee Chuah is affiliated with KU Leuven in Belgium and conducts research primarily within the fields of Biochemistry, Genetics, and Molecular Biology as well as Medicine. Their work is distributed across multiple subfields, including Molecular Biology, Genetics, Oncology, Physiology, and Cellular and Molecular Neuroscience.

The scientist's publications prominently feature topics such as virus-based gene therapy research, CRISPR and genetic engineering, CAR-T cell therapy research, viral infectious diseases and gene expression in insects, muscle physiology and disorders, lysosomal storage disorders research, and neurogenetic and muscular disorders research.

Marinee Chuah has contributed articles to various academic venues, with notable frequencies in Molecular Therapy, Human Gene Therapy, and Molecular Therapy - Methods & Clinical Development. Additional venues include UNC Libraries and Nature Communications.

Key recent papers include:

  • Identification of a myotropic AAV by massively parallel in vivo evaluation of barcoded capsid variants (2020, Nature Communications)
  • Semirational bioengineering of AAV vectors with increased potency and specificity for systemic gene therapy of muscle disorders (2022, Science Advances)
  • Universal allogeneic CAR T cells engineered with Sleeping Beauty transposons and CRISPR-CAS9 for cancer immunotherapy (2022, Molecular Therapy)
  • Hemophilia Gene Therapy: The End of the Beginning? (2023, Human Gene Therapy)
  • Treatment of infantile-onset Pompe disease in a rat model with muscle-directed AAV gene therapy (2024, Molecular Metabolism)

Frequent co-authors collaborating with Marinee Chuah include Thierry VandenDriessche, Quang Hong Pham, Warut Tulalamba, Jihad El Andari, and Dirk Grimm.

Best Publications

  • Molecular evolution of a novel hyperactive Sleeping Beauty transposase enables robust stable gene transfer in vertebrates

    Lajos Mátés;Marinee K L Chuah;Eyayu Belay;Boris Jerchow

  • Lentiviral vectors containing the human immunodeficiency virus type-1 central polypurine tract can efficiently transduce nondividing hepatocytes and antigen-presenting cells in vivo

    Thierry VandenDriessche;Lieven Thorrez;Luigi Naldini;Antonia Follenzi

  • Nanoparticles for the delivery of genes and drugs to human hepatocytes

    Tadanori Yamada;Yasushi Iwasaki;Hiroko Tada;Hidehiko Iwabuki

  • Comparative analysis of transposable element vector systems in human cells

    Ivana Grabundzija;Markus Irgang;Lajos Mátés;Eyayu Belay

  • Long-term expression of human coagulation factor VIII and correction of hemophilia A after in vivo retroviral gene transfer in factor VIII-deficient mice

    Thierry VandenDriessche;Veerle Vanslembrouck;Inge Goovaerts;Hans Zwinnen

  • Efficacy and safety of adeno-associated viral vectors based on serotype 8 and 9 vs. lentiviral vectors for hemophilia B gene therapy.

    T. Vandendriessche;L. Thorrez;A. Acosta-Sanchez;I. Petrus

  • Codon optimization of human factor VIII cDNAs leads to high-level expression

    Natalie J. Ward;Suzanne M. K. Buckley;Simon N. Waddington;Thierry VandenDriessche;Thierry VandenDriessche

  • Therapeutic factor VIII levels and negligible toxicity in mouse and dog models of hemophilia A following gene therapy with high-capacity adenoviral vectors

    Marinee K L Chuah;Gudrun Schiedner;Lieven Thorrez;Brian Brown

  • Gene therapy for cardiovascular disease: advances in vector development, targeting, and delivery for clinical translation

    Melvin Y. Rincon;Thierry VandenDriessche;Thierry VandenDriessche;Marinee K. Chuah;Marinee K. Chuah

  • Emerging potential of transposons for gene therapy and generation of induced pluripotent stem cells

    Thierry VandenDriessche;Zoltán Ivics;Zsuzsanna Izsvák;Marinee K. L. Chuah

  • Identification of a myotropic AAV by massively parallel in vivo evaluation of barcoded capsid variants

    Jonas Weinmann;Sabrina Weis;Josefine Sippel;Warut Tulalamba

  • Long-term persistence of human bone marrow stromal cells transduced with factor VIII-retroviral vectors and transient production of therapeutic levels of human factor VIII in nonmyeloablated immunodeficient mice

    Marinee K.L. Chuah;An Van Damme;Hans Zwinnen;Inge Goovaerts

  • Hepatocyte-targeted expression by integrase-defective lentiviral vectors induces antigen-specific tolerance in mice with low genotoxic risk

    Janka Mátrai;Alessio Cantore;Cynthia C. Bartholomae;Andrea Annoni

  • Differential Effects of Progenitor Cell Populations on Left Ventricular Remodeling and Myocardial Neovascularization After Myocardial Infarction

    Christophe Dubois;Xiaoshun Liu;Piet Claus;Glenn Marsboom

  • Efficient Lentiviral Transduction and Improved Engraftment of Human Bone Marrow Mesenchymal Cells

    An Van Damme;Lieven Thorrez;Ling Ma;Herman Vandenburgh;Herman Vandenburgh

  • IL-10 dampens TNF/inducible nitric oxide synthase-producing dendritic cell-mediated pathogenicity during parasitic infection.

    Martin Guilliams;Kiavash Movahedi;Tom Bosschaerts;Thierry VandenDriessche;Thierry VandenDriessche

  • Liver-Directed Lentiviral Gene Therapy in a Dog Model of Hemophilia B

    Alessio Cantore;Marco Ranzani;Cynthia C. Bartholomae;Monica Volpin

  • Bone marrow stromal cells as targets for gene therapy.

    An Van Damme;Thierry Vanden Driessche;Desire Collen;Marinee K.L. Chuah

  • Inhibition of clinical human immunodeficiency virus (HIV) type 1 isolates in primary CD4+ T lymphocytes by retroviral vectors expressing anti-HIV genes.

    T. Vandendriessche;M. K. L. Chuah;L. Chiang;Hsiao-Kuey Chang

  • Atonal homolog 1 is a tumor suppressor gene.

    Wouter Bossuyt;Avedis Kazanjian;Natalie De Geest;Sofie Van Kelst

Frequent Co-Authors

Thierry VandenDriessche
Thierry VandenDriessche Vrije Universiteit Brussel
Desire Collen
Desire Collen KU Leuven
Luigi Naldini
Luigi Naldini Vita-Salute San Raffaele University
Zsuzsanna Izsvák
Zsuzsanna Izsvák Max Delbrück Center for Molecular Medicine
Herman H. Vandenburgh
Herman H. Vandenburgh Brown University
David Lillicrap
David Lillicrap Queen's University
George Dickson
George Dickson Royal Holloway University of London
Beat Thöny
Beat Thöny University of Zurich

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