D-Index & Metrics Best Publications
Biology and Biochemistry
Belgium
2023
Medicine
Belgium
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 144 Citations 83,674 778 World Ranking 800 National Ranking 7
Biology and Biochemistry D-index 138 Citations 78,170 729 World Ranking 192 National Ranking 4

Research.com Recognitions

Awards & Achievements

2023 - Research.com Medicine in Belgium Leader Award

2023 - Research.com Biology and Biochemistry in Belgium Leader Award

2022 - Research.com Medicine in Belgium Leader Award

1989 - Member of Academia Europaea

Member of the European Molecular Biology Organization (EMBO)

Overview

What is she best known for?

The fields of study she is best known for:

  • Internal medicine
  • Gene
  • Enzyme

Her primary scientific interests are in Internal medicine, Plasminogen activator, Endocrinology, Immunology and Fibrinolysis. Her biological study spans a wide range of topics, including Gastroenterology and Cardiology. Her studies in Plasminogen activator integrate themes in fields like Molecular biology, Tissue plasminogen activator, Activator and Urokinase.

Her studies deal with areas such as Vascular endothelial growth factor A, Vascular endothelial growth factor and Angiogenesis as well as Endocrinology. Desire Collen combines subjects such as Placental growth factor, Endothelium and Cell biology with her study of Angiogenesis. Her Fibrinolysis research is multidisciplinary, relying on both Plasminogen Inactivators, Staphylokinase, Plasmin and Fibrin.

Her most cited work include:

  • Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele (3700 citations)
  • Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis. (2107 citations)
  • Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions (1431 citations)

What are the main themes of her work throughout her whole career to date?

Her primary areas of investigation include Internal medicine, Plasminogen activator, Molecular biology, Endocrinology and Biochemistry. Her Internal medicine study frequently links to other fields, such as Cardiology. Her Plasminogen activator study combines topics from a wide range of disciplines, such as Plasmin, Urokinase, Thrombolysis, Fibrinolysis and Tissue plasminogen activator.

Her Fibrinolysis research is multidisciplinary, incorporating perspectives in Immunology and Fibrin. Her Molecular biology research includes elements of Monoclonal antibody, Plasminogen activator inhibitor-1 and Recombinant DNA. Desire Collen has included themes like Vascular endothelial growth factor A and Vascular endothelial growth factor in her Angiogenesis study.

She most often published in these fields:

  • Internal medicine (31.79%)
  • Plasminogen activator (29.98%)
  • Molecular biology (20.14%)

What were the highlights of her more recent work (between 2002-2020)?

  • Internal medicine (31.79%)
  • Endocrinology (16.40%)
  • Immunology (13.57%)

In recent papers she was focusing on the following fields of study:

Her primary areas of study are Internal medicine, Endocrinology, Immunology, Cancer research and Cell biology. Her study connects Cardiology and Internal medicine. The various areas that Desire Collen examines in her Endocrinology study include Matrix metalloproteinase and In vivo.

Her Immunology study combines topics in areas such as Urokinase receptor, Genetic enhancement and Plasmin. Her Angiogenesis research is multidisciplinary, incorporating elements of Cancer, Endothelium and Vascular endothelial growth factor. Her research ties Plasminogen activator and Myocardial infarction together.

Between 2002 and 2020, her most popular works were:

  • VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death (768 citations)
  • Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1 (672 citations)
  • Anti-PlGF Inhibits Growth of VEGF(R)-Inhibitor-Resistant Tumors without Affecting Healthy Vessels (668 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Internal medicine
  • Enzyme

Desire Collen mostly deals with Internal medicine, Endocrinology, Immunology, Angiogenesis and Cancer research. Her research on Internal medicine often connects related topics like Cardiology. The Endocrinology study combines topics in areas such as Transgene and Heart failure.

Her Immunology research incorporates themes from Metastasis, Genetic enhancement and Coagulation. Her Angiogenesis research incorporates elements of Vascular endothelial growth factor A, Placental growth factor, Vascular endothelial growth factor and Endothelium. The Plasminogen activator study which covers Thrombosis that intersects with Clinical trial, Fibrinolysis and Tissue plasminogen activator.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

Peter Carmeliet;Valérie Ferreira;Georg Breier;Saskia Pollefeyt.
Nature (1996)

5255 Citations

Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis.

Peter Carmeliet;Yuval Dor;Jean-Marc Herbert;Dai Fukumura.
Nature (1998)

3206 Citations

Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions

Peter Carmeliet;Lieve Moons;Aernout Luttun;Valeria Vincenti.
Nature Medicine (2001)

2035 Citations

Cloning and expression of human tissue-type plasminogen activator cDNA in E. coli

Diane Pennica;William E. Holmes;William J. Kohr;Richard N. Harkins.
Nature (1983)

1819 Citations

Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis.

Peter Carmeliet;Maria Grazia Lampugnani;Lieve Moons;Ferrucio Breviario.
Cell (1999)

1554 Citations

On the regulation and control of fibrinolysis. Edward Kowalski Memorial Lecture.

D Collen.
Thrombosis and Haemostasis (1980)

1505 Citations

Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1

Aernout Luttun;Marc Tjwa;Lieve Moons;Yan Wu.
Nature Medicine (2002)

1378 Citations

Molecular mechanisms of blood vessel growth

Edward M. Conway;Désiré Collen;Peter Carmeliet.
Cardiovascular Research (2001)

1363 Citations

Physiological consequences of loss of plasminogen activator gene function in mice.

Peter Carmeliet;Peter Carmeliet;Luc Schoonjans;Lena Kieckens;Beverly Ream.
Nature (1994)

1258 Citations

Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration

B. Oosthuyse;L. Moons;E. Storkebaum;H. Beck.
Nature Genetics (2001)

1220 Citations

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