Florea Lupu

Overview

Best Publications

• Extracellular histones are major mediators of death in sepsis

  Jun Xu;Xiaomei Zhang;Rosana Pelayo;Marc Monestier

  1714
  Citations

• Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis.

  Peter Carmeliet;Maria Grazia Lampugnani;Lieve Moons;Ferrucio Breviario

  1610
  Citations

• Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration

  B. Oosthuyse;L. Moons;E. Storkebaum;H. Beck

  1270
  Citations

• Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure.

  Stephane Heymans;Aernout Luttun;Dieter Nuyens;G Theilmeier

  1007
  Citations

• Loss of HIF-2α and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice

  Veerle Compernolle;Koen Brusselmans;Till Acker;Peter Hoet

  971
  Citations

• Impaired myocardial angiogenesis and ischemic cardiomyopathy in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188.

  Peter Carmeliet;Yin Shan Ng;Dieter Nuyens;Gregor Theilmeier

  867
  Citations

• Urokinase-generated plasmin activates matrix metalloproteinases during aneurysm formation

  Peter Carmeliet;Lieve Moons;Roger Lijnen;Myriam Baes

  809
  Citations

• Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism

  Julián Aragonés;Martin Schneider;Martin Schneider;Martin Schneider;Katie Van Geyte;Katie Van Geyte;Peter Fraisl;Peter Fraisl

  560
  Citations

• Deficiency or inhibition of Gas6 causes platelet dysfunction and protects mice against thrombosis.

  Anne Angelillo-Scherrer;Pablo Garcia de Frutos;Cristina Aparicio;Els Melis

  532
  Citations

• Prelesional events in atherogenesis: accumulation of extracellular cholesterol-rich liposomes in the arterial intima and cardiac valves of the hyperlipidemic rabbit

  N Simionescu;E Vasile;F Lupu;G Popescu

  365
  Citations

• Localization and production of plasminogen activator inhibitor-1 in human healthy and atherosclerotic arteries.

  Florea Lupu;Gabriela E. Bergonzelli;Dominik A. Heim;Elisabeth Cousin

  353
  Citations

• Podoplanin maintains high endothelial venule integrity by interacting with platelet CLEC-2

  Brett H. Herzog;Jianxin Fu;Jianxin Fu;Stephen J. Wilson;Paul R. Hess

  352
  Citations

• Inhibitory Role of Plasminogen Activator Inhibitor-1 in Arterial Wound Healing and Neointima Formation A Gene Targeting and Gene Transfer Study in Mice

  Peter Carmeliet;Lieve Moons;Roger Lijnen;Stefaan Janssens

  348
  Citations

• Persistence of Atherosclerotic Plaque but Reduced Aneurysm Formation in Mice With Stromelysin-1 (MMP-3) Gene Inactivation

  J. Silence;F. Lupu;D. Collen;H.R. Lijnen

  310
  Citations

• Function of the Plasminogen/Plasmin and Matrix Metalloproteinase Systems After Vascular Injury in Mice With Targeted Inactivation of Fibrinolytic System Genes

  H. Roger Lijnen;Berthe Van Hoef;Florea Lupu;Lieve Moons

  284
  Citations

• Innate immunity and coagulation

  Charles T. Esmon;Jun Xu;Florea Lupu

  281
  Citations

• Urokinase but Not Tissue Plasminogen Activator Mediates Arterial Neointima Formation in Mice

  Peter Carmeliet;Lieve Moons;Jean-Marc Herbert;James Crawley

  277
  Citations

• A genetic Xenopus laevis tadpole model to study lymphangiogenesis

  Annelii Ny;Marta Koch;Marta Koch;Martin Schneider;Martin Schneider;Elke Neven;Elke Neven

  273
  Citations

• Endothelial cell O-glycan deficiency causes blood/lymphatic misconnections and consequent fatty liver disease in mice

  Jianxin Fu;Holger Gerhardt;J. Michael McDaniel;Baoyun Xia

  269
  Citations

• Plasminogen Activator Expression in Human Atherosclerotic Lesions

  Florea Lupu;Dominik A. Heim;Fedor Bachmann;Michel Hurni

  255
  Citations