Jean-Marc Herbert

Overview

Best Publications

• Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis.

  Peter Carmeliet;Yuval Dor;Jean-Marc Herbert;Dai Fukumura

  3339
  Citations

• Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions

  Peter Carmeliet;Lieve Moons;Aernout Luttun;Valeria Vincenti

  2114
  Citations

• Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis.

  Peter Carmeliet;Maria Grazia Lampugnani;Lieve Moons;Ferrucio Breviario

  1610
  Citations

• Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1

  Aernout Luttun;Marc Tjwa;Lieve Moons;Yan Wu

  1426
  Citations

• Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration

  B. Oosthuyse;L. Moons;E. Storkebaum;H. Beck

  1270
  Citations

• Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1

  Monica Autiero;Johannes Waltenberger;Didier Communi;Andrea Kranz

  1015
  Citations

• Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure.

  Stephane Heymans;Aernout Luttun;Dieter Nuyens;G Theilmeier

  1007
  Citations

• Peroxisome Proliferator-activated Receptor α Activators Improve Insulin Sensitivity and Reduce Adiposity

  Michèle Guerre-Millo;Philippe Gervois;Eric Raspé;Lise Madsen

  917
  Citations

• Structure and stereochemistry of the active metabolite of clopidogrel

  Jean-Marie Pereillo;Mohamed Maftouh;Alain Andrieu;Marie-Francoise Uzabiaga

  642
  Citations

• Deficiency or inhibition of Gas6 causes platelet dysfunction and protects mice against thrombosis.

  Anne Angelillo-Scherrer;Pablo Garcia de Frutos;Cristina Aparicio;Els Melis

  532
  Citations

• The lectin-like domain of thrombomodulin confers protection from neutrophil-mediated tissue damage by suppressing adhesion molecule expression via nuclear factor kappaB and mitogen-activated protein kinase pathways.

  Edward Conway;Marlies Lutgart Julien Van de Wouwer;Saskia Pollefeyt;Kerstin Jurk

  487
  Citations

• Clopidogrel and ticlopidine: P2Y12 adenosine diphosphate-receptor antagonists for the prevention of atherothrombosis

  Pierre Savi;Jean-Marc Herbert

  449
  Citations

• Synthesis of thrombin-inhibiting heparin mimetics without side effects

  Maurice Petitou;Jean-Pascal Hérault;André Bernat;Pierre-Alexandre Driguez

  447
  Citations

• Rimonabant reduces obesity-associated hepatic steatosis and features of metabolic syndrome in obese Zucker fa/fa rats.

  Magali Gary-Bobo;Ghizlane Elachouri;Jean François Gallas;Philip Janiak

  424
  Citations

• The active metabolite of Clopidogrel disrupts P2Y12 receptor oligomers and partitions them out of lipid rafts

  Pierre Savi;Jean-Luc Zachayus;Nathalie Delesque-Touchard;Catherine Labouret

  419
  Citations

• The antiaggregating activity of clopidogrel is due to a metabolic activation by the hepatic cytochrome P450-1A.

  Savi P;Combalbert J;Gaich C;Rouchon Mc

  397
  Citations

• Neuropilin-2 interacts with VEGFR-2 and VEGFR-3 and promotes human endothelial cell survival and migration.

  Benoit Favier;Antoine Alam;Pauline Barron;Jacques Bonnin

  371
  Citations

• Specific Impairment of Human Platelet P2YAC ADP Receptor–Mediated Signaling by the Antiplatelet Drug Clopidogrel

  J. Geiger;J. Brich;P. Hönig-Liedl;M. Eigenthaler

  364
  Citations

• P2y(12), a new platelet ADP receptor, target of clopidogrel.

  P. Savi;C. Labouret;N. Delesque;F. Guette

  358
  Citations

• VEGF-B is dispensable for blood vessel growth but critical for their survival, and VEGF-B targeting inhibits pathological angiogenesis

  Fan Zhang;Zhongshu Tang;Xu Hou;Johan Lennartsson

  342
  Citations