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Hideaki Tahara

Hideaki Tahara

D-Index & Metrics

Immunology

D-Index
67
Citations
16937
World Ranking
2661
National Ranking
106

Overview

Hideaki Tahara is affiliated with the University of Tokyo in Japan and has a research focus primarily in the fields of Medicine, Biochemistry, Genetics and Molecular Biology, and Immunology and Microbiology. Their work concentrates on oncology, molecular biology, and immunology, with specific attention to subfields such as pulmonary and respiratory medicine and genetics.

The scientist's research topics cover areas including immunotherapy and immune responses, immune cell function and interaction, peptidase inhibition and analysis, immune cells in cancer, chromatin remodeling and cancer, cancer immunotherapy and biomarkers, as well as virus-based gene therapy research.

Frequent publication venues for their work include Cancer Science, Immunotherapy, JTO Clinical and Research Reports, Cancer Immunology Immunotherapy, and Molecular Therapy - Oncolytics.

Hideaki Tahara has collaborated regularly with several co-authors, which include:

  • Yu Mizote
  • Takashi Akazawa
  • Keiichiro Honma
  • Tomoya Ekawa
  • Kei Kunimasa

Among the recent papers associated with their research are:

  • Atezolizumab with bevacizumab, paclitaxel and carboplatin was effective for patients with SMARCA4-deficient thoracic sarcoma (2021, Immunotherapy)
  • Conversion Surgery for Advanced Thoracic SMARCA4-Deficient Undifferentiated Tumor With Atezolizumab in Combination With Bevacizumab, Paclitaxel, and Carboplatin Treatment: A Case Report (2021, JTO Clinical and Research Reports)
  • The liposome of trehalose dimycolate extracted from M. bovis BCG induces antitumor immunity via the activation of dendritic cells and CD8+ T cells (2021, Cancer Immunology Immunotherapy)
  • Cancer-derived cholesterol sulfate is a key mediator to prevent tumor infiltration by effector T cells (2022, International Immunology)
  • Potent anti-tumor effects of receptor-retargeted syncytial oncolytic herpes simplex virus (2021, Molecular Therapy - Oncolytics)

Best Publications

  • Interleukin-17 promotes angiogenesis and tumor growth.

    Muneo Numasaki;Jun Ichi Fukushi;Mayumi Ono;Satwant K. Narula

  • Recombinant IL-12 administration induces tumor regression in association with IFN-gamma production.

    C L Nastala;H D Edington;T G McKinney;H Tahara

  • Expression of E-cadherin cell adhesion molecules in human breast cancer tissues and its relationship to metastasis

    Hiroshi Oka;Hitoshi Shiozaki;Kenji Kobayashi;Masatoshi Inoue

  • Phase I evaluation of intravenous recombinant human interleukin 12 in patients with advanced malignancies.

    Michael B. Atkins;Michael J. Robertson;Michael Gordon;Michael T. Lotze

  • Tumor-associated macrophages regulate tumorigenicity and anticancer drug responses of cancer stem/initiating cells

    Masahisa Jinushi;Shigeki Chiba;Hironori Yoshiyama;Kenkichi Masutomi

  • Viral vectors for gene therapy

    Paul D. Robbins;Hideaki Tahara;Steven C. Ghivizzani

  • Fibroblasts genetically engineered to secrete interleukin 12 can suppress tumor growth and induce antitumor immunity to a murine melanoma in vivo.

    Hideaki Tahara;Herbert J. Zeh;Walter J. Storkus;Itzhak Pappo

  • IFN-gamma-inducing factor/IL-18 administration mediates IFN-gamma- and IL-12-independent antitumor effects.

    Tadashi Osaki;Jean Marie Péron;Quan Cai;Haruki Okamura

  • Effective eradication of established murine tumors with IL-12 gene therapy using a polycistronic retroviral vector.

    H. Tahara;L. Zitvogel;W. J. Storkus;H. J. Zeh

  • Induction of systemic and therapeutic antitumor immunity using intratumoral injection of dendritic cells genetically modified to express interleukin 12

    Yasuhiko Nishioka;Motohiro Hirao;Paul D. Robbins;Michael T. Lotze

  • Adenovirus-Mediated Transfer of siRNA against Survivin Induced Apoptosis and Attenuated Tumor Cell Growth in Vitro and in Vivo

    Hiroaki Uchida;Hiroaki Uchida;Toshihiro Tanaka;Katsunori Sasaki;Kazunori Kato

  • Systemic administration of cellular IL-10 induces an effective, specific, and long-lived immune response against established tumors in mice.

    Robert M. Berman;Tadamichi Suzuki;Hideaki Tahara;Paul D. Robbins

  • Differential Antitumor Effects of Administration of Recombinant IL-18 or Recombinant IL-12 Are Mediated Primarily by Fas-Fas Ligand- and Perforin-Induced Tumor Apoptosis, Respectively

    Wataru Hashimoto;Tadashi Osaki;Tadashi Osaki;Haruki Okamura;Paul D. Robbins

  • Viral interleukin 10 (IL-10), the human herpes virus 4 cellular IL-10 homologue, induces local anergy to allogeneic and syngeneic tumors.

    Tadamichi Suzuki;Hideaki Tahara;Satwant Narula;Kevin W. Moore

  • Retrovirus-mediated transfer of viral IL-10 gene prolongs murine cardiac allograft survival

    Lihui Qin;Kenneth D. Chavin;Yaozhong Ding;Hideaki Tahara

  • Toll-like receptor 3 signaling converts tumor-supporting myeloid cells to tumoricidal effectors

    Hiroaki Shime;Misako Matsumoto;Hiroyuki Oshiumi;Shinya Tanaka

  • Cancer immunotherapy of established tumors with IL-12. Effective delivery by genetically engineered fibroblasts.

    L Zitvogel;H Tahara;P D Robbins;W J Storkus

  • Retroviral delivery of viral interleukin-10 into myeloid dendritic cells markedly inhibits their allostimulatory activity and promotes the induction of T-cell hyporesponsiveness.

    Takuya Takayama;Yasuhiko Nishioka;Lina Lu;Michael T. Lotze

  • CC chemokine receptor-7 on dendritic cells is induced after interaction with apoptotic tumor cells: critical role in migration from the tumor site to draining lymph nodes.

    Motohiro Hirao;Nobuyuki Onai;Kazumasa Hiroishi;Simon C. Watkins

  • Antitumor effects of interleukin-12 (IL-12): applications for the immunotherapy and gene therapy of cancer.

    H Tahara;M T Lotze

Frequent Co-Authors

Michael T. Lotze
Michael T. Lotze University of Pittsburgh
Paul D. Robbins
Paul D. Robbins University of Minnesota
Walter J. Storkus
Walter J. Storkus University of Pittsburgh
Angus W. Thomson
Angus W. Thomson University of Pittsburgh
Masabumi Shibuya
Masabumi Shibuya Jobu University
Yusuke Nakamura
Yusuke Nakamura National Institutes of Biomedical Innovation, Health and Nutrition
Laurence Zitvogel
Laurence Zitvogel University of Paris-Saclay
Yoshihiro Hayakawa
Yoshihiro Hayakawa Aichi Institute of Technology
Haruki Okamura
Haruki Okamura Hyogo College of Medicine
Theresa L. Whiteside
Theresa L. Whiteside University of Pittsburgh

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