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Immunology

D-Index
85
Citations
25614
World Ranking
1320
National Ranking
682

Medicine

D-Index
85
Citations
25641
World Ranking
14645
National Ranking
7410

Overview

Walter J. Storkus is affiliated with the University of Pittsburgh in the United States and has an extensive research portfolio in medicine, particularly focusing on immunology and oncology. Their scholarly work spans multiple subfields, including immunology, oncology, molecular biology, pulmonary and respiratory medicine, and surgery.

The primary topics covered in Storkus's research include:

  • Cancer Immunotherapy and Biomarkers
  • Immunotherapy and Immune Responses
  • CAR-T Cell Therapy Research
  • Immune Cell Function and Interaction
  • Cutaneous Melanoma Detection and Management
  • Interferon and Immune Responses
  • Immune Cells in Cancer

Storkus has contributed to a number of recent papers that reflect these interests:

  • "STING Agonists as Cancer Therapeutics," 2021, published in Cancers
  • "Epigenetic modulation of antitumor immunity for improved cancer immunotherapy," 2021, published in Molecular Cancer
  • "STING agonist-based treatment promotes vascular normalization and tertiary lymphoid structure formation in the therapeutic melanoma microenvironment," 2021, published in Journal for ImmunoTherapy of Cancer
  • "Bi- and Tri-Specific T Cell Engager-Armed Oncolytic Viruses: Next-Generation Cancer Immunotherapy," 2020, published in Biomedicines
  • "Dendritic cell vaccines targeting tumor blood vessel antigens in combination with dasatinib induce therapeutic immune responses in patients with checkpoint-refractory advanced melanoma," 2021, published in Journal for ImmunoTherapy of Cancer

Among frequent co-authors associated with Storkus are:

  • John M. Kirkwood
  • J Filderman
  • Lilit Karapetyan
  • Ahmad A. Tarhini
  • Cindy Sander

The scientist's research is frequently published in the following venues:

  • Regular and Young Investigator Award Abstracts
  • Journal for ImmunoTherapy of Cancer
  • The Journal of Immunology
  • Frontiers in Immunology
  • Journal of Clinical Oncology

Walter J. Storkus has also authored a book published by Frontiers Media titled "Immunotherapy in Renal Cell Carcinoma" released in 2023.

Best Publications

  • Bone marrow-derived dendritic cells pulsed with synthetic tumour peptides elicit protective and therapeutic antitumour immunity

    J I Mayordomo;T Zorina;W J Storkus;L Zitvogel

  • Therapy of murine tumors with tumor peptide-pulsed dendritic cells: dependence on T cells, B7 costimulation, and T helper cell 1-associated cytokines.

    L. Zitvogel;J. I. Mayordomo;Tjendimin Tjandrawan;A. B. Deleo

  • Peptide-pulsed dendritic cells induce antigen-specific CTL-mediated protective tumor immunity.

    Christina M. Celluzzi;Jose I. Mayordomo;Walter J. Storkus;Michael T. Lotze

  • Recombinant IL-12 administration induces tumor regression in association with IFN-gamma production.

    C L Nastala;H D Edington;T G McKinney;H Tahara

  • Tumor-Derived Microvesicles Promote Regulatory T Cell Expansion and Induce Apoptosis in Tumor-Reactive Activated CD8+ T Lymphocytes

    Eva U. Wieckowski;Carmen Visus;Marta Szajnik;Miroslaw J. Szczepanski

  • α-Type-1 Polarized Dendritic Cells A Novel Immunization Tool with Optimized CTL-inducing Activity

    Robbie B. Mailliard;Anna Wankowicz-Kalinska;Quan Cai;Amy Wesa

  • NK susceptibility varies inversely with target cell class I HLA antigen expression.

    W J Storkus;D N Howell;R D Salter;J R Dawson

  • Dendritic cells mediate NK cell help for Th1 and CTL responses: two-signal requirement for the induction of NK cell helper function.

    Robbie B. Mailliard;Young Ik Son;Richard Redlinger;Patrick T. Coates

  • Fibroblasts genetically engineered to secrete interleukin 12 can suppress tumor growth and induce antitumor immunity to a murine melanoma in vivo.

    Hideaki Tahara;Herbert J. Zeh;Walter J. Storkus;Itzhak Pappo

  • Tumor escape from immune recognition: lethal recurrent melanoma in a patient associated with downregulation of the peptide transporter protein TAP-1 and loss of expression of the immunodominant MART-1/Melan-A antigen.

    Markus J. Maeurer;Susanne M. Gollin;Dina Martin;William Swaney

  • Immunologic monitoring of cancer vaccine therapy: results of a workshop sponsored by the Society for Biological Therapy.

    Ulrich Keilholz;Jeffrey Weber;James H. Finke;Dmitry I. Gabrilovich

  • Disease-associated Bias in T Helper Type 1 (Th1)/Th2 CD4+ T Cell Responses Against MAGE-6 in HLA-DRB10401+ Patients With Renal Cell Carcinoma or Melanoma

    Tomohide Tatsumi;Lisa S. Kierstead;Elena Ranieri;Elena Ranieri;Loreto Gesualdo

  • STING Agonists as Cancer Therapeutics.

    Afsaneh Amouzegar;Manoj Chelvanambi;Jessica N. Filderman;Walter J. Storkus

  • Effective eradication of established murine tumors with IL-12 gene therapy using a polycistronic retroviral vector.

    H. Tahara;L. Zitvogel;W. J. Storkus;H. J. Zeh

  • Reversal of natural killing susceptibility in target cells expressing transfected class I HLA genes

    W. J. Storkus;J. Alexander;John A Payne;J. R. Dawson

  • Autologous Human Monocyte-Derived Dendritic Cells Genetically Modified to Express Melanoma Antigens Elicit Primary Cytotoxic T Cell Responses In Vitro: Enhancement by Cotransfection of Genes Encoding the Th1-Biasing Cytokines IL-12 and IFN-α

    Thomas Tüting;Cara C. Wilson;Dina M. Martin;Yvette L. Kasamon

  • Therapy of murine tumors with p53 wild-type and mutant sequence peptide-based vaccines.

    J I Mayordomo;D J Loftus;H Sakamoto;C M De Cesare

  • Immunopolarization of CD4(+) and CD8(+) T cells to type-1-like is associated with melanocyte loss in human vitiligo

    Anna Wańkowicz-Kalińska;René M J G J van den Wijngaard;Bert J Tigges;Wiete Westerhof

  • Identification of T-cell epitopes: rapid isolation of class I-presented peptides from viable cells by mild acid elution.

    Walter J. Storkus;Herbert J. Zeh;Russell D. Salter;Michael T. Lotze

  • Vaccinia virus-mediated cancer immunotherapy: cancer vaccines and oncolytics

    Zong Sheng Guo;Binfeng Lu;Zongbi Guo;Esther Giehl

  • Toll like receptor-3 ligand poly-ICLC promotes the efficacy of peripheral vaccinations with tumor antigen-derived peptide epitopes in murine CNS tumor models

    Xinmei Zhu;Fumihiko Nishimura;Kotaro Sasaki;Mitsugu Fujita

  • Mass spectrometric identification of a naturally processed melanoma peptide recognized by CD8+ cytotoxic T lymphocytes.

    Chiara Castelli;Walter J. Storkus;Markus J. Maeurer;Dina M. Martin

Frequent Co-Authors

Michael T. Lotze
Michael T. Lotze University of Pittsburgh
Hideho Okada
Hideho Okada University of California, San Francisco
John M. Kirkwood
John M. Kirkwood University of Pittsburgh
Paul D. Robbins
Paul D. Robbins University of Minnesota
Theresa L. Whiteside
Theresa L. Whiteside University of Pittsburgh
Laurence Zitvogel
Laurence Zitvogel University of Paris-Saclay
Hideaki Tahara
Hideaki Tahara University of Tokyo
Simon C. Watkins
Simon C. Watkins University of Pittsburgh
Markus Maeurer
Markus Maeurer Champalimaud Foundation
Pawel Kalinski
Pawel Kalinski Roswell Park Comprehensive Cancer Center

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