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Immunology
Netherlands
2026
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Medicine
Netherlands
2023

D-Index & Metrics

Immunology

D-Index
136
Citations
71004
World Ranking
186
National Ranking
6

Medicine

D-Index
136
Citations
70996
World Ranking
1974
National Ranking
75

Research.com Recognitions

  • 2026 - Research.com Immunology in Netherlands Leader Award
  • 2025 - Research.com Immunology in Netherlands Leader Award
  • 2023 - Research.com Medicine in Netherlands Leader Award
  • 2022 - Research.com Immunology in Netherlands Leader Award

Overview

Cornelis J. M. Melief is affiliated with ISA Pharmaceuticals in the Netherlands. Their research primarily focuses on Medicine, with notable contributions across several subfields including Infectious Diseases, Nutrition and Dietetics, Neurology, Immunology, and Oncology.

The scientist's recent publications cover a range of topics related to immunotherapy, infectious disease responses, and cancer. Noteworthy papers include:

  • Reactive oxygen species as an initiator of toxic innate immune responses in retort to SARS-CoV-2 in an ageing population, consider N-acetylcysteine as early therapeutic intervention (2020, Toxicology Reports)
  • Editorial: Novel Strategies for Anti-Tumor Vaccines (2020, Frontiers in Immunology)

The topics addressed in their work encompass:

  • COVID-19 Clinical Research Studies
  • Vitamin C and Antioxidants Research
  • Long-Term Effects of COVID-19
  • Immunotherapy and Immune Responses
  • Cancer Immunotherapy and Biomarkers
  • Vaccines and Immunoinformatics Approaches

Frequent co-authors who have collaborated with Melief include Aikaterini Nasi, Stéphanie McArdle, Gustav Gaudernack, Gabriel Westman, and Johan Rockberg.

The venues where Melief has published include:

  • Toxicology Reports
  • Frontiers in Immunology

Best Publications

  • B lymphocytes secrete antigen-presenting vesicles.

    G Raposo;H W Nijman;W Stoorvogel;R Liejendekker

  • T-cell help for cytotoxic T lymphocytes is mediated by CD40–CD40L interactions

    S. P. Schoenberger;R. E. M. Toes;E. I. H. Van Der Voort;R. Offringa

  • Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens

    Matthew M. Gubin;Xiuli Zhang;Heiko Schuster;Etienne Caron

  • CD4 + T cell help in cancer immunology and immunotherapy

    Jannie Borst;Tomasz Ahrends;Nikolina Bąbała;Cornelis J. M. Melief

  • Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses.

    R. P.M. Sutmuller;L. M. Van Duivenvoorde;A. Van Elsas;T. N.M. Schumacher

  • Bone marrow-derived dendritic cells pulsed with synthetic tumour peptides elicit protective and therapeutic antitumour immunity

    J I Mayordomo;T Zorina;W J Storkus;L Zitvogel

  • Vaccination against HPV-16 Oncoproteins for Vulvar Intraepithelial Neoplasia

    Gemma G Kenter;Marij J P Welters;A Rob P M Valentijn;Margriet J G Lowik

  • Dendritic cell immunotherapy: mapping the way

    Carl G Figdor;I Jolanda M de Vries;W Joost Lesterhuis;Cornelis J M Melief

  • Therapeutic cancer vaccines

    Cornelis J.M. Melief;Thorbald van Hall;Ramon Arens;Ferry Ossendorp

  • The relationship between class I binding affinity and immunogenicity of potential cytotoxic T cell epitopes.

    A. Sette;A. Vitiello;B. Reherman;P. Fowler

  • Vaccination with cytotoxic T lymphocyte epitope‐containing peptide protects against a tumor induced by human papillomavirus type 16‐transformed cells

    M. C. W. Feltkamp;H. L. Smits;M. P. M. Vierboom;R. P. Minnaar

  • Specific T Helper Cell Requirement for Optimal Induction of Cytotoxic T Lymphocytes against Major Histocompatibility Complex Class II Negative Tumors

    Ferry Ossendorp;Erica Mengedé;Marcel Camps;Rian Filius

  • Vaccines for established cancer: overcoming the challenges posed by immune evasion.

    Sjoerd H. van der Burg;Ramon Arens;Ferry Ossendorp;Thorbald van Hall

  • Immunotherapy of established (pre)malignant disease by synthetic long peptide vaccines

    Cornelis J.M. Melief;Sjoerd H. van der Burg

  • Decreased tumor surveillance in perforin-deficient mice.

    M. F. Van Den Broek;D. Kagi;F. Ossendorp;R. Toes

  • Cancer Immunotherapy by Dendritic Cells

    Cornelis J.M. Melief

  • CD4 T cells and their role in antitumor immune responses.

    René E.M. Toes;Ferry Ossendorp;Rienk Offringa;Cornelis J.M. Melief

  • Autoimmune destruction of skin melanocytes by perilesional T cells from vitiligo patients.

    Jasper G. van den Boorn;Debby Konijnenberg;Trees A.M. Dellemijn;J.P. Wietze van der Veen

  • Established Human Papillomavirus Type 16-Expressing Tumors Are Effectively Eradicated Following Vaccination with Long Peptides

    Sander Zwaveling;Sandra C. Ferreira Mota;Jan Nouta;Mark Johnson

  • CD40 activation in vivo overcomes peptide-induced peripheral cytotoxic T-lymphocyte tolerance and augments anti-tumor vaccine efficacy.

    Diehl L;den Boer At;Schoenberger Sp;van der Voort Ei

Frequent Co-Authors

Sjoerd H. van der Burg
Sjoerd H. van der Burg Leiden University Medical Center
Rienk Offringa
Rienk Offringa German Cancer Research Center
Ferry Ossendorp
Ferry Ossendorp Leiden University Medical Center
Jan W. Drijfhout
Jan W. Drijfhout Leiden University Medical Center
René E. M. Toes
René E. M. Toes Leiden University Medical Center
Marij J. P. Welters
Marij J. P. Welters Leiden University Medical Center
Gemma G. Kenter
Gemma G. Kenter Vrije Universiteit Amsterdam
W. Martin Kast
W. Martin Kast University of Southern California
Kees L. M. C. Franken
Kees L. M. C. Franken Leiden University Medical Center
Gert Jan Fleuren
Gert Jan Fleuren Leiden University Medical Center

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