World's Best Scientists 2026 revealed!

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Immunology

D-Index
109
Citations
42828
World Ranking
520
National Ranking
316

Medicine

D-Index
109
Citations
42828
World Ranking
5793
National Ranking
3110

Overview

John Sidney is affiliated with the La Jolla Institute For Allergy & Immunology in the United States. Their research primarily focuses on immunology and infectious diseases with a particular emphasis on T-cell and B-cell immunology, vaccines, and immune responses related to SARS-CoV-2 and COVID-19.

Their main fields of study include Medicine, Immunology and Microbiology, and Biochemistry, Genetics and Molecular Biology. Subfields emphasized in their work comprise Immunology, Molecular Biology, Infectious Diseases, Epidemiology, and Neurology.

John Sidney has contributed extensively to the study of immune mechanisms and vaccine responses, especially in the context of the SARS-CoV-2 virus. Notable recent papers include:

  • Selective and cross-reactive SARS-CoV-2 T cell epitopes in unexposed humans (2020, Science)
  • A Sequence Homology and Bioinformatic Approach Can Predict Candidate Targets for Immune Responses to SARS-CoV-2 (2020, Cell Host & Microbe)
  • SARS-CoV-2 vaccination induces immunological T cell memory able to cross-recognize variants from Alpha to Omicron (2022, Cell)
  • Impact of SARS-CoV-2 variants on the total CD4+ and CD8+ T cell reactivity in infected or vaccinated individuals (2021, Cell Reports Medicine)
  • Comprehensive analysis of T cell immunodominance and immunoprevalence of SARS-CoV-2 epitopes in COVID-19 cases (2021, Cell Reports Medicine)

Their frequent co-authors include Alessandro Sette, Alba Grifoni, Bjoern Peters, S. Mallal, and Daniela Weiskopf. These collaborations reflect consistent contributions to the research community focused on immunology and infectious disease.

John Sidney's works have been published predominantly in venues such as bioRxiv (Cold Spring Harbor Laboratory), Cell Host & Microbe, Cell, The Journal of Immunology, and UNC Libraries.

Main research topics covered by Sidney involve:

  • Vaccines and immunoinformatics approaches
  • Immunotherapy and immune responses
  • SARS-CoV-2 and COVID-19 research
  • T-cell and B-cell immunology
  • Immune cell function and interaction
  • COVID-19 clinical research studies
  • Monoclonal and polyclonal antibodies research

Best Publications

  • Selective and cross-reactive SARS-CoV-2 T cell epitopes in unexposed humans.

    Jose Mateus;Alba Grifoni;Alison Tarke;John Sidney

  • A Sequence Homology and Bioinformatic Approach Can Predict Candidate Targets for Immune Responses to SARS-CoV-2

    Alba Grifoni;John Sidney;Yun Zhang;Richard H. Scheuermann

  • A Systematic Assessment of MHC Class II Peptide Binding Predictions and Evaluation of a Consensus Approach

    Peng Wang;John Sidney;Courtney Dow;Courtney Dow;Bianca Mothé

  • Predicting population coverage of T-cell epitope-based diagnostics and vaccines

    Huynh-Hoa Bui;John Sidney;Kenny Dinh;Scott Southwood

  • NetMHCpan, a method for MHC class I binding prediction beyond humans

    Ilka Hoof;Bjoern Peters;John Sidney;Lasse Eggers Pedersen

  • T cells from patients with Parkinson’s disease recognize α-synuclein peptides

    David Sulzer;Roy N. Alcalay;Francesca Garretti;Lucien Cote

  • HLA class I supertypes: a revised and updated classification

    John Sidney;Bjoern Peters;Nicole Frahm;Christian Brander

  • Peptide binding predictions for HLA DR, DP and DQ molecules

    Peng Wang;John Sidney;Yohan Kim;Alessandro Sette

  • Comprehensive analysis of dengue virus-specific responses supports an HLA-linked protective role for CD8+ T cells

    Daniela Weiskopf;Michael A. Angelo;Elzinandes L. de Azeredo;John Sidney

  • Mass Spectrometry Profiling of HLA-Associated Peptidomes in Mono-allelic Cells Enables More Accurate Epitope Prediction.

    Jennifer G. Abelin;Derin B. Keskin;Siranush Sarkizova;Christina R. Hartigan

  • A consensus epitope prediction approach identifies the breadth of murine T(CD8+)-cell responses to vaccinia virus.

    Magdalini Moutaftsi;Bjoern Peters;Valerie Pasquetto;David C Tscharke

  • Development of an epitope conservancy analysis tool to facilitate the design of epitope-based diagnostics and vaccines

    Huynh-Hoa Bui;Huynh-Hoa Bui;John Sidney;Wei Li;Nicholas Fusseder

  • Comprehensive analysis of T cell immunodominance and immunoprevalence of SARS-CoV-2 epitopes in COVID-19 cases.

    Alison Tarke;Alison Tarke;John Sidney;Conner K. Kidd;Jennifer M. Dan;Jennifer M. Dan

  • Impact of SARS-CoV-2 variants on the total CD4 + and CD8 + T cell reactivity in infected or vaccinated individuals.

    Alison Tarke;Alison Tarke;John Sidney;Nils Methot;Esther Dawen Yu

  • The outcome of hepatitis C virus infection is predicted by escape mutations in epitopes targeted by cytotoxic T lymphocytes.

    Ann L Erickson;Yoichi Kimura;Suzu Igarashi;Jennifer Eichelberger

  • Virus-specific cytotoxic T-lymphocyte responses select for amino-acid variation in simian immunodeficiency virus Env and Nef.

    David T. Evans;David T. Evans;David H. O'Connor;Peicheng Jing;John L. Dzuris

  • Key Parameters of Tumor Epitope Immunogenicity Revealed Through a Consortium Approach Improve Neoantigen Prediction

    Daniel K. Wells;Marit M. van Buuren;Kristen K. Dang;Vanessa M. Hubbard-Lucey

  • The immune epitope database and analysis resource: from vision to blueprint.

    Bjoern Peters;John Sidney;Phil Bourne;Huynh-Hoa Bui

  • Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire

    David A. Ostrov;Barry J. Grant;Yuri A. Pompeu;John Sidney

  • Reversion of CTL escape-variant immunodeficiency viruses in vivo.

    Thomas C Friedrich;Elizabeth J Dodds;Levi J Yant;Lara Vojnov

  • A large fraction of HLA class I ligands are proteasome-generated spliced peptides

    Juliane Liepe;Fabio Marino;John Sidney;Anita Jeko

Frequent Co-Authors

Alessandro Sette
Alessandro Sette La Jolla Institute For Allergy & Immunology
Bjoern Peters
Bjoern Peters La Jolla Institute For Allergy & Immunology
Carla Oseroff
Carla Oseroff La Jolla Institute For Allergy & Immunology
Simon Mallal
Simon Mallal Vanderbilt University Medical Center
Daniela Weiskopf
Daniela Weiskopf La Jolla Institute For Allergy & Immunology
Howard M. Grey
Howard M. Grey La Jolla Institute For Allergy & Immunology
Elizabeth J. Phillips
Elizabeth J. Phillips Vanderbilt University Medical Center
Scott Southwood
Scott Southwood Johnson & Johnson
Jason A. Greenbaum
Jason A. Greenbaum La Jolla Institute For Allergy & Immunology
Alba Grifoni
Alba Grifoni La Jolla Institute For Allergy & Immunology

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