World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
54
Citations
12099
World Ranking
15520
National Ranking
625

Overview

Laurent Prézeau is affiliated with the University of Montpellier in France. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, Neuroscience, and Medicine, with a focus on Molecular Biology and Cellular and Molecular Neuroscience as subfields. The scientist's work also touches on Oncology, Radiology, Nuclear Medicine and Imaging, and Surgery.

Prézeau's research topics include:

  • Receptor Mechanisms and Signaling
  • Neuroscience and Neuropharmacology Research
  • Photoreceptor and Optogenetics Research
  • Monoclonal and Polyclonal Antibodies Research
  • Click Chemistry and Applications
  • Pharmacological Receptor Mechanisms and Effects
  • HER2/EGFR in Cancer Research

Their recent notable publications cover a range of studies in molecular receptor biology and signaling mechanisms. These include:

  • "Biased signaling due to oligomerization of the G protein-coupled platelet-activating factor receptor" (2022) published in Nature Communications
  • "G protein-coupled receptors can control the Hippo/YAP pathway through Gq signaling" (2021) published in The FASEB Journal
  • "A nanobody activating metabotropic glutamate receptor 4 discriminates between homo- and heterodimers" (2021) published in Proceedings of the National Academy of Sciences
  • "Targeting the Brain with Single-Domain Antibodies: Greater Potential Than Stated So Far?" (2023) published in International Journal of Molecular Sciences
  • "SGIP1 modulates kinetics and interactions of the cannabinoid receptor 1 and G protein-coupled receptor kinase 3 signalosome" (2021) published in Journal of Neurochemistry

Frequently publishing in various venues, their work has appeared multiple times in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • The FASEB Journal
  • Proceedings of the National Academy of Sciences
  • International Journal of Molecular Sciences

Collaborations play a role in their research output, with frequent co-authors including:

  • Jean-Philippe Pin
  • Philippe Rondard
  • Pierre-André Lafon
  • Junke Liu
  • Marta Cimadevila

Best Publications

  • Evolution, structure, and activation mechanism of family 3/C G-protein-coupled receptors.

    Jean-Philippe Pin;Thierry Galvez;Laurent Prézeau

  • Cell-surface protein-protein interaction analysis with time-resolved FRET and snap-tag technologies: application to GPCR oligomerization.

    Damien Maurel;Laëtitia Comps-Agrar;Laëtitia Comps-Agrar;Carsten Brock;Carsten Brock;Marie-Laure Rives;Marie-Laure Rives

  • Nitric oxide-induced blockade of NMDA receptors.

    Olivier Manzoni;Laurent Prezeau;Philippe Marin;Solange Deshager

  • Agonist-independent activation of metabotropic glutamate receptors by the intracellular protein Homer

    F. Ango;L. Prézeau;T. Muller;J. C. Tu

  • CPCCOEt, a noncompetitive metabotropic glutamate receptor 1 antagonist, inhibits receptor signaling without affecting glutamate binding.

    Stephane Litschig;Fabrizio Gasparini;Doris Rueegg;Natacha Stoehr

  • Allosteric interactions between GB1 and GB2 subunits are required for optimal GABAB receptor function

    Thierry Galvez;Béatrice Duthey;Julie Kniazeff;Jaroslav Blahos

  • Closed state of both binding domains of homodimeric mGlu receptors is required for full activity

    Julie Kniazeff;Anne-Sophie Bessis;Damien Maurel;Hervé Ansanay

  • The non-competitive antagonists 2-methyl-6-(phenylethynyl)pyridine and 7-hydroxyiminocyclopropan[b]chromen-1a-carboxylic acid ethyl ester interact with overlapping binding pockets in the transmembrane region of group I metabotropic glutamate receptors

    Adriana Pagano;Adriana Pagano;Doris Rüegg;Stephane Litschig;Natacha Stoehr

  • C-terminal interaction is essential for surface trafficking but not for heteromeric assembly of GABA(b) receptors.

    Adriana Pagano;Giorgio Rovelli;Johannes Mosbacher;Tania Lohmann;Tania Lohmann

  • Alternative splicing generates metabotropic glutamate receptors inducing different patterns of calcium release in Xenopus oocytes.

    Jean-Philippe Pin;Christian Waeber;Laurent Prezeau;Joel Bockaert

  • Dimers and beyond: The functional puzzles of class C GPCRs.

    Julie Kniazeff;Laurent Prézeau;Philippe Rondard;Jean-Philippe Pin

  • A single subunit (GB2) is required for G protein activation by the heterodimeric GABAB receptor

    Béatrice Duthey;Sara Caudron;Julie Perroy;Bernhard Bettler

  • The Heptahelical Domain of GABAB2 Is Activated Directly by CGP7930, a Positive Allosteric Modulator of the GABAB Receptor *

    Virginie Binet;Carole Brajon;Laurent Le Corre;Francine Acher

  • Evidence for a single heptahelical domain being turned on upon activation of a dimeric GPCR

    Veronika Hlavackova;Veronika Hlavackova;Cyril Goudet;Julie Kniazeff;Alice Zikova

  • Heptahelical domain of metabotropic glutamate receptor 5 behaves like rhodopsin-like receptors

    Cyril Goudet;Florence Gaven;Julie Kniazeff;Claire Vol

  • Changes in the carboxyl-terminal domain of metabotropic glutamate receptor 1 by alternative splicing generate receptors with differing agonist-independent activity.

    L Prézeau;J Gomeza;S Ahern;S Mary

  • Allosteric functioning of dimeric class C G-protein-coupled receptors

    J.-P. Pin;J. Kniazeff;J. Liu;V. Binet

  • BAY36-7620: a potent non-competitive mGlu1 receptor antagonist with inverse agonist activity.

    Fiona Y. Carroll;Andreas Stolle;Philip M. Beart;Arnd Voerste

  • Asymmetric functioning of dimeric metabotropic glutamate receptors disclosed by positive allosteric modulators.

    Cyril Goudet;Julie Kniazeff;Veronika Hlavackova;Fanny Malhaire

  • A model for the functioning of family 3 GPCRs

    Marie-Laure Parmentier;Laurent Prézeau;Joël Bockaert;Jean-Philippe Pin

Frequent Co-Authors

Jean-Philippe Pin
Jean-Philippe Pin University of Montpellier
Joël Bockaert
Joël Bockaert University of Montpellier
Bernhard Bettler
Bernhard Bettler University of Basel
Olivier J. Manzoni
Olivier J. Manzoni Aix-Marseille University
Jianfeng Liu
Jianfeng Liu China-Japan Friendship Hospital
Paul F. Worley
Paul F. Worley Johns Hopkins University School of Medicine
Wolfgang Froestl
Wolfgang Froestl AC Immune (Switzerland)
Klemens Kaupmann
Klemens Kaupmann Novartis (Switzerland)
Philippe Marin
Philippe Marin University of Montpellier
Martin Gassmann
Martin Gassmann University of Basel

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