Klemens Kaupmann

Overview

Best Publications

• GABAB-RECEPTOR SUBTYPES ASSEMBLE INTO FUNCTIONAL HETEROMERIC COMPLEXES

  Klemens Kaupmann;Barbara Malitschek;Valerie Schuler;Jakob Heid

  1456
  Citations

• Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptors.

  Klemens Kaupmann;Katharina Huggel;Jakob Heid;Peter J. Flor

  1255
  Citations

• Molecular Structure and Physiological Functions of GABAB Receptors

  Bernhard Bettler;Klemens Kaupmann;Johannes Mosbacher;Martin Gassmann

  1174
  Citations

• Epilepsy, hyperalgesia, impaired memory, and loss of pre- and postsynaptic GABA(B) responses in mice lacking GABA(B(1))

  Valérie Schuler;Christian Lüscher;Christophe Blanchet;Norman Klix

  641
  Citations

• Don't worry ‘B’ happy!: a role for GABAB receptors in anxiety and depression

  John F. Cryan;Klemens Kaupmann

  540
  Citations

• GABAB receptors - the first 7TM heterodimers.

  Fiona H Marshall;Kenneth A Jones;Klemens Kaupmann;Bernhard Bettler

  449
  Citations

• Genetic and Pharmacological Evidence of a Role for GABA B Receptors in the Modulation of Anxiety- and Antidepressant-Like Behavior

  Cedric Mombereau;Klemens Kaupmann;Wolfgang Froestl;Gilles Sansig

  443
  Citations

• THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein-coupled receptors

  Stephen P.H. Alexander;Arthur Christopoulos;Anthony P. Davenport;Eamonn Kelly

  427
  Citations

• Positive allosteric modulation of native and recombinant gamma-aminobutyric acid(B) receptors by 2,6-Di-tert-butyl-4-(3-hydroxy-2,2-dimethyl-propyl)-phenol (CGP7930) and its aldehyde analog CGP13501.

  Stephan Urwyler;Johannes Mosbacher;Kurt Lingenhoehl;Jakob Heid

  389
  Citations

• C-terminal interaction is essential for surface trafficking but not for heteromeric assembly of GABA(b) receptors.

  Adriana Pagano;Giorgio Rovelli;Johannes Mosbacher;Tania Lohmann;Tania Lohmann

  377
  Citations

• Differential Compartmentalization and Distinct Functions of GABAB Receptor Variants

  Réjan Vigot;Samuel Barbieri;Hans Bräuner-Osborne;Rostislav Turecek;Rostislav Turecek

  374
  Citations

• LRRK2 protein levels are determined by kinase function and are crucial for kidney and lung homeostasis in mice

  Martin C. Herzig;Carine Kolly;Elke Persohn;Diethilde Theil

  365
  Citations

• Behavioral Characterization of the Novel GABAB Receptor-Positive Modulator GS39783 (N,N′-Dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine): Anxiolytic-Like Activity without Side Effects Associated with Baclofen or Benzodiazepines

  John F. Cryan;Peter H. Kelly;Frederique Chaperon;Conrad Gentsch

  306
  Citations

• Redistribution of GABAB(1) Protein and Atypical GABAB Responses in GABAB(2)-Deficient Mice

  Martin Gassmann;Hamdy Shaban;Réjan Vigot;Gilles Sansig

  276
  Citations

• N,N′-Dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine (GS39783) and Structurally Related Compounds: Novel Allosteric Enhancers of γ-Aminobutyric AcidB Receptor Function

  Stephan Urwyler;Mario F. Pozza;Kurt Lingenhoehl;Johannes Mosbacher

  274
  Citations

• Spatial distribution of GABA(B)R1 receptor mRNA and binding sites in the rat brain

  S Bischoff;S Leonhard;N Reymann;V Schuler

  255
  Citations

• Mutagenesis and modeling of the GABAB receptor extracellular domain support a venus flytrap mechanism for ligand binding

  Thierry Galvez;Marie-Laure Parmentier;Cécile Joly;Barbara Malitschek

  253
  Citations

• Generalization of amygdala LTP and conditioned fear in the absence of presynaptic inhibition.

  Hamdy Shaban;Yann Humeau;Yann Humeau;Cyril Herry;Guillaume Cassasus

  243
  Citations

• Spatial distribution of GABABR1 receptor mRNA and binding sites in the rat brain

  Serge Bischoff;Sabine Leonhard;Nicole Reymann;Valérie Schuler

  237
  Citations

• Molecular Pharmacology of Somatostatin‐receptor Subtypes

  Christian Bruns;Gisbert Weckbecker;Friedrich Raulf;Klemens Kaupmann

  206
  Citations