D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 48 Citations 12,393 82 World Ranking 11214 National Ranking 194

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Genetics

Klemens Kaupmann mainly focuses on GABAB receptor, Receptor, Neuroscience, Agonist and Metabotropic receptor. The GABAB receptor study combines topics in areas such as Receptor antagonist, Ion channel, Binding site and Cell biology. Much of his study explores Receptor relationship to Endocrinology.

His Neuroscience study incorporates themes from Protein subunit, Alternative splicing, Pathophysiology, splice and Extracellular proteins. His Agonist research incorporates themes from Muscle relaxation and Pharmacology. His study in Metabotropic receptor is interdisciplinary in nature, drawing from both Metabotropic glutamate receptor 1 and Metabotropic glutamate receptor.

His most cited work include:

  • GABAB-RECEPTOR SUBTYPES ASSEMBLE INTO FUNCTIONAL HETEROMERIC COMPLEXES (1069 citations)
  • Expression cloning of GABA B receptors uncovers similarity to metabotropic glutamate receptors (957 citations)
  • Molecular Structure and Physiological Functions of GABAB Receptors (699 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Receptor, GABAB receptor, Biochemistry, Internal medicine and Endocrinology. Klemens Kaupmann does research in Receptor, focusing on Metabotropic receptor specifically. His Metabotropic receptor research includes elements of Metabotropic glutamate receptor 1 and Inhibitory postsynaptic potential.

His research integrates issues of Allosteric regulation, Neuroscience and Pharmacology in his study of GABAB receptor. His Neuroscience research incorporates elements of Long-term potentiation, Pathophysiology, G protein-coupled receptor and Metabotropic glutamate receptor. Many of his research projects under Internal medicine are closely connected to Identity with Identity, tying the diverse disciplines of science together.

He most often published in these fields:

  • Receptor (54.39%)
  • GABAB receptor (45.61%)
  • Biochemistry (23.68%)

What were the highlights of his more recent work (between 2012-2020)?

  • Receptor (54.39%)
  • RAR-related orphan receptor gamma (6.14%)
  • In vivo (5.26%)

In recent papers he was focusing on the following fields of study:

Receptor, RAR-related orphan receptor gamma, In vivo, Cell biology and Inverse agonist are his primary areas of study. His Receptor study introduces a deeper knowledge of Biochemistry. His In vivo study integrates concerns from other disciplines, such as Nuclear receptor, Transcription and Drug discovery.

His work carried out in the field of Inverse agonist brings together such families of science as Imidazopyridine, Stereochemistry and Transcription factor. Klemens Kaupmann combines subjects such as Baclofen, Dopamine, Habituation and Ventral tegmental area with his study of GABAB receptor. In the field of Agonist, his study on Metabotropic glutamate receptor 1, Metabotropic glutamate receptor 6 and Metabotropic glutamate receptor 7 overlaps with subjects such as GABA receptor antagonist.

Between 2012 and 2020, his most popular works were:

  • Blocking Metabotropic Glutamate Receptor Subtype 7 (mGlu7) via the Venus Flytrap Domain (VFTD) inhibits Amygdala Plasticity, Stress and Anxiety-related Behavior (47 citations)
  • Pharmacological inhibition of RORγt suppresses the Th17 pathway and alleviates arthritis in vivo. (26 citations)
  • Structural States of RORγt: X-ray Elucidation of Molecular Mechanisms and Binding Interactions for Natural and Synthetic Compounds. (22 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Genetics

His main research concerns RAR-related orphan receptor gamma, Agonist, Transcription factor, Inverse agonist and Cell biology. The study incorporates disciplines such as Apoptosis, Cancer research, Downregulation and upregulation and Cytokine in addition to RAR-related orphan receptor gamma. His biological study focuses on Metabotropic glutamate receptor 1.

His studies in Transcription factor integrate themes in fields like Ex vivo, Receptor, Helix and Molecular biology. The various areas that he examines in his Inverse agonist study include Nuclear receptor and In vivo. Cell biology and Genetics are frequently intertwined in his study.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

GABAB-RECEPTOR SUBTYPES ASSEMBLE INTO FUNCTIONAL HETEROMERIC COMPLEXES

Klemens Kaupmann;Barbara Malitschek;Valerie Schuler;Jakob Heid.
Nature (1998)

1363 Citations

Expression cloning of GABA B receptors uncovers similarity to metabotropic glutamate receptors

Klemens Kaupmann;Katharina Huggel;Jakob Heid;Peter J. Flor.
Nature (1997)

1176 Citations

Molecular Structure and Physiological Functions of GABAB Receptors

Bernhard Bettler;Klemens Kaupmann;Johannes Mosbacher;Martin Gassmann.
Physiological Reviews (2004)

979 Citations

Epilepsy, hyperalgesia, impaired memory, and loss of pre- and postsynaptic GABA(B) responses in mice lacking GABA(B(1))

Valérie Schuler;Christian Lüscher;Christophe Blanchet;Norman Klix.
Neuron (2001)

587 Citations

Don't worry ‘B’ happy!: a role for GABAB receptors in anxiety and depression

John F. Cryan;Klemens Kaupmann.
Trends in Pharmacological Sciences (2005)

465 Citations

GABAB receptors - the first 7TM heterodimers.

Fiona H Marshall;Kenneth A Jones;Klemens Kaupmann;Bernhard Bettler.
Trends in Pharmacological Sciences (1999)

427 Citations

Genetic and Pharmacological Evidence of a Role for GABA B Receptors in the Modulation of Anxiety- and Antidepressant-Like Behavior

Cedric Mombereau;Klemens Kaupmann;Wolfgang Froestl;Gilles Sansig.
Neuropsychopharmacology (2004)

391 Citations

Positive Allosteric Modulation of Native and Recombinant γ-Aminobutyric AcidB Receptors by 2,6-Di-tert-butyl-4-(3-hydroxy-2,2-dimethyl-propyl)-phenol (CGP7930) and its Aldehyde Analog CGP13501

Stephan Urwyler;Johannes Mosbacher;Kurt Lingenhoehl;Jakob Heid.
Molecular Pharmacology (2001)

372 Citations

C-terminal interaction is essential for surface trafficking but not for heteromeric assembly of GABA(b) receptors.

Adriana Pagano;Giorgio Rovelli;Johannes Mosbacher;Tania Lohmann;Tania Lohmann.
The Journal of Neuroscience (2001)

356 Citations

Differential Compartmentalization and Distinct Functions of GABAB Receptor Variants

Réjan Vigot;Samuel Barbieri;Hans Bräuner-Osborne;Rostislav Turecek;Rostislav Turecek.
Neuron (2006)

334 Citations

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