Andreas Billich

Overview

Best Publications

• Fingolimod (FTY720): discovery and development of an oral drug to treat multiple sclerosis

  Volker Brinkmann;Andreas Billich;Thomas Baumruker;Peter Heining

  1712
  Citations

• Comparison of human skin or epidermis models with human and animal skin in in-vitro percutaneous absorption.

  Fritz P. Schmook;Josef G. Meingassner;Andreas Billich

  678
  Citations

• Phosphorylation of the immunomodulatory drug FTY720 by sphingosine kinases.

  Andreas Billich;Frederic Bornancin;Piroska Dévay;Diana Mechtcheriakova

  620
  Citations

• Persistent signaling induced by FTY720-phosphate is mediated by internalized S1P1 receptors

  Florian Mullershausen;Frédéric Zecri;Cihan Cetin;Andreas Billich

  482
  Citations

• Sphingosine kinase type 2 is essential for lymphopenia induced by the immunomodulatory drug FTY720

  Barbara Zemann;Bernd Kinzel;Matthias Müller;Roland Reuschel

  378
  Citations

• Mode of Action of SDZ NIM 811, a Nonimmunosuppressive Cyclosporin A Analog with Activity against Human Immunodeficiency Virus (HIV) Type 1: Interference with HIV Protein-Cyclophilin A Interactions

  A Billich;F Hammerschmid;P Peichl;R Wenger

  262
  Citations

• Percutaneous absorption of drugs used in atopic eczema: pimecrolimus permeates less through skin than corticosteroids and tacrolimus.

  Andreas Billich;Heinrich Aschauer;András Aszódi;Anton Stuetz

  240
  Citations

• PIKfyve, a class III PI kinase, is the target of the small molecular IL-12/IL-23 inhibitor apilimod and a player in Toll-like receptor signaling.

  Xinming Cai;Yongyao Xu;Atwood K. Cheung;Ronald C. Tomlinson

  216
  Citations

• Presence of Cyclophilin A in Synovial Fluids of Patients with Rheumatoid Arthritis

  Andreas Billich;Gottfried Winkler;Heinrich Aschauer;Antal Rot

  209
  Citations

• Basal and induced sphingosine kinase 1 activity in A549 carcinoma cells: function in cell survival and IL-1beta and TNF-alpha induced production of inflammatory mediators.

  Andreas Billich;Frédéric Bornancin;Diana Mechtcheriakova;François Natt

  189
  Citations

• Ovalbumin-induced plasma interleukin-4 levels are reduced in ceramide kinase-deficient DO11.10 RAG1 -/- mice

  Satoru Niwa;Nicole Urtz;Thomas Baumruker;Andreas Billich

  187
  Citations

• A novel role of sphingosine 1-phosphate receptor S1pr1 in mouse thrombopoiesis

  Lin Zhang;Lin Zhang;Martin Orban;Martin Orban;Michael Lorenz;Michael Lorenz;Verena Barocke;Verena Barocke

  176
  Citations

• Sphingosine 1-phosphate phosphatase 2 is induced during inflammatory responses.

  Diana Mechtcheriakova;Alexander Wlachos;Jury Sobanov;Tamara Kopp

  175
  Citations

• Steroid sulfatase inhibitors

  Peter Nussbaumer;Andreas Billich

  170
  Citations

• Second generation S1P pathway modulators: research strategies and clinical developments.

  Marc Bigaud;Danilo Guerini;Andreas Billich;Frederic Bassilana

  169
  Citations

• Sanglifehrin A, a Novel Cyclophilin-Binding Compound Showing Immunosuppressive Activity with a New Mechanism of Action

  Gerhard Zenke;Ulrike Strittmatter;Serge Fuchs;Valerie F. J. Quesniaux

  163
  Citations

• 2-Substituted 4-(thio)chromenone 6-O-sulfamates: potent inhibitors of human steroid sulfatase.

  Peter Nussbaumer;Philipp Lehr;Andreas Billich

  157
  Citations

• Mode of action of SDZ NIM 811, a nonimmunosuppressive cyclosporin A analog with activity against human immunodeficiency virus type 1 (HIV-1): interference with early and late events in HIV-1 replication.

  A Steinkasserer;R Harrison;A Billich;F Hammerschmid

  152
  Citations

• Synthesis of borondipyrromethene (BODIPY)-labeled sphingosine derivatives by cross-metathesis reaction

  Carsten Peters;Andreas Billich;Michael Ghobrial;Klemens Högenauer

  135
  Citations

• Stimulation of MCF-7 breast cancer cell proliferation by estrone sulfate and dehydroepiandrosterone sulfate: inhibition by novel non-steroidal steroid sulfatase inhibitors.

  Andreas Billich;Peter Nussbaumer;Philipp Lehr

  134
  Citations