2026 Hugh Rosen: Biology and Biochemistry Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Biology and Biochemistry	87	2837	2612	1457	1313	258	26596

Overview

Hugh Rosen is affiliated with the Scripps Research Institute in the United States. Their research spans multiple fields within biochemistry, genetics, molecular biology, neuroscience, and medicine with a focus on molecular mechanisms and cellular processes.

Their main fields of study include:

Biochemistry, Genetics and Molecular Biology
Medicine
Neuroscience

Within these broad areas, their subfields of study cover:

Molecular Biology
Physiology
Cellular and Molecular Neuroscience
Cognitive Neuroscience
Cell Biology

Rosen's work is particularly concentrated on topics such as:

Sphingolipid Metabolism and Signaling
Pain Mechanisms and Treatments
Neuropeptides and Animal Physiology
Lipid Membrane Structure and Behavior
Sleep and Wakefulness Research
Ion channel regulation and function
Endoplasmic Reticulum Stress and Disease

Their recent publications illustrate a focus on neurobiology and immunological mechanisms:

"Chronic pain recruits hypothalamic dynorphin/kappa opioid receptor signalling to promote wakefulness and vigilance," 2022, Brain
"Opposing Effects on Descending Control of Nociception by µ and κ Opioid Receptors in the Anterior Cingulate Cortex," 2023, Anesthesiology
"The riddle of the Sphinx: why sphingosine-1-phosphate may help define molecular mechanisms underlying risk stratification for serious COVID-19 infections," 2020, EMBO Molecular Medicine
"S1P₁ Contributes to Endotoxin-enhanced B-Cell Functions Involved in Hypersensitivity Pneumonitis," 2020, American Journal of Respiratory Cell and Molecular Biology
"The discovery and development of the sphingosine 1-phosphate receptor modulator ozanimod in ulcerative colitis," 2024, Advances in pharmacology

The frequent coauthors with whom Rosen collaborates include:

Edita Navratilova
Miguel Guerrero
Volker Neugebauer
Frank Porreca
Hisakatsu Ito

Publication venues where Rosen has contributed multiple times reflect the interdisciplinary nature of their research:

Brain
Anesthesiology
EMBO Molecular Medicine
American Journal of Respiratory Cell and Molecular Biology
Advances in pharmacology

Best Publications

Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists.

Suzanne Mandala;Richard Hajdu;James Bergstrom;Elizabeth Quackenbush

1954
Citations
Sphingosine 1-phosphate and its receptors: an autocrine and paracrine network

Hugh Rosen;Edward J. Goetzl

811
Citations
Crystal Structure of a Lipid G Protein–Coupled Receptor

Michael A. Hanson;Christopher B. Roth;Euijung Jo;Mark T. Griffith

798
Citations
Endothelial cells are central orchestrators of cytokine amplification during influenza virus infection

John R. Teijaro;Kevin B. Walsh;Stuart M. Cahalan;Daniel M. Fremgen

783
Citations
Absence of Wallerian Degeneration does not Hinder Regeneration in Peripheral Nerve.

E. R. Lunn;V. H. Perry;M. C. Brown;H. Rosen

774
Citations
Sphingosine 1-Phosphate (S1P) Receptor Subtypes S1P1 and S1P3, Respectively, Regulate Lymphocyte Recirculation and Heart Rate

M. Germana Sanna;Jiayu Liao;Euijung Jo;Christopher Alfonso

747
Citations
Importance of cellular microenvironment and circulatory dynamics in B cell immunotherapy.

Qian Gong;Qinglin Ou;Shiming Ye;Wyne P. Lee

644
Citations
The function of follicular helper T cells is regulated by the strength of T cell antigen receptor binding

Nicolas Fazilleau;Louise J McHeyzer-Williams;Hugh Rosen;Michael G McHeyzer-Williams

559
Citations
Resistance to fever induction and impaired acute-phase response in interleukin-1β-deficient mice

Hui Zheng;Daniel Fletcher;Wieslaw Kozak;Minghao Jiang

496
Citations
Sphingosine 1-Phosphate Receptor Signaling

Hugh Rosen;Pedro J. Gonzalez-Cabrera;M. Germana Sanna;Steven Brown

494
Citations
Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P 1 antagonist in vivo

M Germana Sanna;Sheng-Kai Wang;Pedro J Gonzalez-Cabrera;Pedro J Gonzalez-Cabrera;Anthony Don

461
Citations
Tumor suppression after tumor cell-targeted tumor necrosis factor alpha gene transfer.

Thomas Blankenstein;Zheng Hong Qin;K Uberla;Werner Muller

413
Citations
Monoclonal antibody to the murine type 3 complement receptor inhibits adhesion of myelomonocytic cells in vitro and inflammatory cell recruitment in vivo.

H Rosen;S Gordon

406
Citations
The Antifungal Echinocandin Caspofungin Acetate Kills Growing Cells of Aspergillus fumigatus In Vitro

J. C. Bowman;P. Scott Hicks;M. B. Kurtz;H. Rosen

398
Citations
Immune Cell Regulation and Cardiovascular Effects of Sphingosine 1-Phosphate Receptor Agonists in Rodents Are Mediated via Distinct Receptor Subtypes

M. Forrest;S.-Y. Sun;R. Hajdu;J. Bergstrom

396
Citations
The GPCR Network: a large-scale collaboration to determine human GPCR structure and function.

Raymond C. Stevens;Vadim Cherezov;Vsevolod Katritch;Ruben Abagyan

377
Citations
Reversible inhibitor of p97, DBeQ, impairs both ubiquitin-dependent and autophagic protein clearance pathways

Tsui-Fen Chou;Steve J. Brown;Dmitriy Minond;Brian E. Nordin

367
Citations
Dendritic cell PAR1–S1P3 signalling couples coagulation and inflammation

Frank Niessen;Florence Schaffner;Christian Furlan-Freguia;Rafal Pawlinski

341
Citations
Two-site binding of C5a by its receptor: An alternative binding paradigm for G protein-coupled receptors

S J Siciliano;T E Rollins;J DeMartino;Z Konteatis

334
Citations
Sphingosine 1-phosphate type 1 receptor agonism inhibits transendothelial migration of medullary T cells to lymphatic sinuses

Sindy H Wei;Hugh Rosen;Melanie P Matheu;M Germana Sanna

321
Citations