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Raymond J. Deshaies

D-Index & Metrics

Biology and Biochemistry

D-Index
104
Citations
47787
World Ranking
1238
National Ranking
733

Raymond J. Deshaies publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Raymond J. Deshaies sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 231 publications — 61st percentile

61% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Raymond J. Deshaies D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Raymond J. Deshaies sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 104 D-Index — 94th percentile

94% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Research.com Recognitions

  • 2016 - Member of the National Academy of Sciences
  • 2011 - Fellow of the American Academy of Arts and Sciences
  • 2007 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Raymond J. Deshaies is affiliated with the California Institute of Technology in the United States. Their research spans key areas in biochemistry, genetics, and molecular biology, with significant contributions to medicine. The primary subfields of focus include molecular biology, epidemiology, cell biology, oncology, and biochemistry.

The scientist's work frequently addresses topics such as ubiquitin and proteasome pathways, protein degradation and inhibitors, endoplasmic reticulum stress and disease, autophagy in disease and therapy, liver disease diagnosis and treatment, lipid metabolism and biosynthesis, and peptidase inhibition and analysis.

Deshaies has published numerous articles in leading scientific venues. Frequent publication outlets include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • UNC Libraries
  • Nature
  • Molecular Cell
  • Proceedings of the National Academy of Sciences

Selected recent papers illustrate the themes and scope of their research:

  • Multispecific drugs herald a new era of biopharmaceutical innovation, 2020, Nature
  • Harnessing the Power of Proteolysis for Targeted Protein Inactivation, 2020, Molecular Cell
  • PIKES Analysis Reveals Response to Degraders and Key Regulatory Mechanisms of the CRL4 Network, 2020, Molecular Cell
  • Assembly and Regulation of CRL Ubiquitin Ligases, 2020, Advances in Experimental Medicine and Biology
  • A covalent p97/VCP ATPase inhibitor can overcome resistance to CB-5083 and NMS-873 in colorectal cancer cells, 2021, European Journal of Medicinal Chemistry

Collaboration is a notable feature of Deshaies' work. Frequent co-authors include:

  • David J. Sherman
  • Rati Verma
  • Michael J. Sweredoski
  • Jiansong Xie
  • John Ferbas

Recognition from the broader scientific community includes membership and fellowships in prestigious organizations. Awards received are:

  • Member of the National Academy of Sciences (2016)
  • Fellow of the American Academy of Arts and Sciences (2011)
  • Fellow of the American Association for the Advancement of Science (AAAS) (2007)

Best Publications

  • RING Domain E3 Ubiquitin Ligases

    Raymond J. Deshaies;Claudio A. P. Joazeiro

  • Function and regulation of cullin-RING ubiquitin ligases.

    Matthew D. Petroski;Raymond J. Deshaies

  • Protacs: chimeric molecules that target proteins to the Skp1-Cullin-F box complex for ubiquitination and degradation.

    Kathleen M. Sakamoto;Kyung B. Kim;Akiko Kumagai;Frank Mercurio

  • A subfamily of stress proteins facilitates translocation of secretory and mitochondrial precursor polypeptides

    Raymond J. Deshaies;Bruce D. Koch;Margaret Werner-Washburne;Elizabeth A. Craig

  • How proteolysis drives the cell cycle

    Randall W. King;Raymond J. Deshaies;Jan-Michael Peters;Marc W. Kirschner

  • SCF and Cullin/RING H2-Based Ubiquitin Ligases

    Raymond J Deshaies

  • Role of Rpn11 Metalloprotease in Deubiquitination and Degradation by the 26S Proteasome

    Rati Verma;L. Aravind;Robert Oania;W. Hayes McDonald

  • A Complex of Cdc4p, Skp1p, and Cdc53p/Cullin Catalyzes Ubiquitination of the Phosphorylated CDK Inhibitor Sic1p

    R.M.Renny Feldman;Craig C Correll;Kenneth B Kaplan;Raymond J Deshaies

  • Exit from Mitosis Is Triggered by Tem1-Dependent Release of the Protein Phosphatase Cdc14 from Nucleolar RENT Complex

    Wenying Shou;Jae Hong Seol;Anna Shevchenko;Christopher Baskerville

  • Role of Predicted Metalloprotease Motif of Jab1/Csn5 in Cleavage of Nedd8 from Cul1

    Gregory A. Cope;Greg S. B. Suh;L. Aravind;Sylvia E. Schwarz

  • Promotion of NEDD8-CUL1 Conjugate Cleavage by COP9 Signalosome

    Svetlana Lyapina;Gregory Cope;Anna Shevchenko;Giovanna Serino

  • Proteasomal Proteomics: Identification of Nucleotide-sensitive Proteasome-interacting Proteins by Mass Spectrometric Analysis of Affinity-purified Proteasomes

    Rati Verma;Stephen Chen;Renny Feldman;David Schieltz

  • Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4

    Zdenek Skrott;Martin Mistrik;Klaus Kaae Andersen;Søren Friis

  • Phosphorylation of Sic1p by G1 Cdk Required for Its Degradation and Entry into S Phase

    R. Verma;R. S. Annan;M. J. Huddleston;S. A. Carr

  • Interactions of the COP9 Signalosome with the E3 Ubiquitin Ligase SCF TIR1 in Mediating Auxin Response

    Claus Schwechheimer;Giovanna Serino;Judy Callis;William L. Crosby

  • Multiubiquitin Chain Receptors Define a Layer of Substrate Selectivity in the Ubiquitin-Proteasome System

    Rati Verma;Robert Oania;Johannes Graumann;Raymond J Deshaies

  • Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34.

    J. H. Seol;R.M. R. Feldman;W. Zachariae;A. Shevchenko

  • Multimodal Activation of the Ubiquitin Ligase SCF by Nedd8 Conjugation

    Anjanabha Saha;Raymond J. Deshaies

  • A yeast mutant defective at an early stage in import of secretory protein precursors into the endoplasmic reticulum.

    R J Deshaies;R Schekman

  • Transcription Factor Nrf1 Mediates the Proteasome Recovery Pathway after Proteasome Inhibition in Mammalian Cells

    Senthil K. Radhakrishnan;Candy S. Lee;Patrick Young;Anne Beskow

Frequent Co-Authors

Sonja Hess
Sonja Hess AstraZeneca (United Kingdom)
Kathleen M. Sakamoto
Kathleen M. Sakamoto Stanford University
Randy Schekman
Randy Schekman University of California, Berkeley
Craig M. Crews
Craig M. Crews Yale University
Seth M. Cohen
Seth M. Cohen University of California, San Diego
Matthias Peter
Matthias Peter ETH Zurich
Hugh Rosen
Hugh Rosen Scripps Research Institute
John R. Yates
John R. Yates Scripps Research Institute
Andrej Shevchenko
Andrej Shevchenko Max Planck Society
Ruedi Aebersold
Ruedi Aebersold ETH Zurich

External Links

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Best Scientists Citing Raymond J. Deshaies

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Harvard Medical School

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Brenda A. Schulman

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Publications: 83

Keiji Tanaka

Keiji Tanaka

Tokyo Metropolitan Institute of Medical Science

Publications: 82

Craig M. Crews

Craig M. Crews

Yale University

Publications: 80

Jeffrey L. Brodsky

Jeffrey L. Brodsky

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Publications: 79

Yi Sun

Yi Sun

Zhejiang University

Publications: 78

Mike Tyers

Mike Tyers

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Publications: 75

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Harvard University

Publications: 62

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Harvard University

Publications: 58

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Harvard University

Publications: 56

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Publications: 53

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Publications: 52

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