D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 44 Citations 14,979 95 World Ranking 15993 National Ranking 6639

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Biochemistry

Michael Rape mostly deals with Cell biology, Ubiquitin, Biochemistry, Anaphase-promoting complex and Ubiquitin ligase. His Ubiquitin research incorporates themes from Cell signaling, Signal transduction and Cell division. Ubiquitin-conjugating enzyme, Transcription factor, Proteasome and Enzyme are subfields of Biochemistry in which his conducts study.

His Ubiquitin-conjugating enzyme study incorporates themes from Deubiquitinating enzyme and SUMO enzymes. His Anaphase-promoting complex study combines topics from a wide range of disciplines, such as Spindle checkpoint and Mitotic checkpoint complex. The Ubiquitin ligase study which covers Plasma protein binding that intersects with Nuclear protein, Cell membrane and Regulon.

His most cited work include:

  • The Ubiquitin Code (1898 citations)
  • Building ubiquitin chains: E2 enzymes at work. (660 citations)
  • Activation of a Membrane-Bound Transcription Factor by Regulated Ubiquitin/Proteasome-Dependent Processing (491 citations)

What are the main themes of his work throughout his whole career to date?

Michael Rape spends much of his time researching Cell biology, Ubiquitin, Ubiquitin ligase, Biochemistry and Ubiquitin-conjugating enzyme. His Cell biology research includes themes of Cell cycle, Cell division and Anaphase-promoting complex. Particularly relevant to Deubiquitinating enzyme is his body of work in Ubiquitin.

His Ubiquitin ligase research is multidisciplinary, incorporating elements of Plasma protein binding, Protein degradation, Cell fate determination and Neural crest. Within one scientific family, he focuses on topics pertaining to Crystal structure under Biochemistry, and may sometimes address concerns connected to Stereochemistry. His Ubiquitin-conjugating enzyme research incorporates elements of Processivity, Ubiquitin-Protein Ligases, Ubiquitins and Active site.

He most often published in these fields:

  • Cell biology (80.19%)
  • Ubiquitin (73.58%)
  • Ubiquitin ligase (50.00%)

What were the highlights of his more recent work (between 2018-2021)?

  • Ubiquitin (73.58%)
  • Cell biology (80.19%)
  • Ubiquitin ligase (50.00%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Ubiquitin, Cell biology, Ubiquitin ligase, Biophysics and Mitosis. His research in Ubiquitin focuses on subjects like Transcription factor, which are connected to Medulloblastoma and Pediatric cancer. He works in the field of Cell biology, namely Proteasome.

His Ubiquitin ligase study combines topics from a wide range of disciplines, such as Small molecule, Protein degradation and Drug discovery. Michael Rape interconnects Proteostasis and Protein folding in the investigation of issues within Biophysics. His study in Mitosis is interdisciplinary in nature, drawing from both Receptor, Mitotic exit, Cell cycle and Cell division.

Between 2018 and 2021, his most popular works were:

  • Branching Out: Improved Signaling by Heterotypic Ubiquitin Chains. (42 citations)
  • Branching Out: Improved Signaling by Heterotypic Ubiquitin Chains. (42 citations)
  • Prospective discovery of small molecule enhancers of an E3 ligase-substrate interaction. (36 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Biochemistry

His main research concerns Cell biology, Ubiquitin, Branching, Virulence and Bacterial outer membrane. The study incorporates disciplines such as Anaphase-promoting complex and Small molecule in addition to Cell biology. His Anaphase-promoting complex study integrates concerns from other disciplines, such as Mitosis and Proteasome.

The Small molecule study combines topics in areas such as Rational design, Enhancer, Transcription factor, DNA ligase and Substrate Interaction. Michael Rape combines topics linked to Ubiquitin ligase with his work on Rational design. Michael Rape has researched Virulence in several fields, including Immune system and Intracellular parasite.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The Ubiquitin Code

David Komander;Michael Rape.
Annual Review of Biochemistry (2012)

3041 Citations

Building ubiquitin chains: E2 enzymes at work.

Yihong Ye;Michael Rape.
Nature Reviews Molecular Cell Biology (2009)

1057 Citations

The increasing complexity of the ubiquitin code

Richard Yau;Michael Rape.
Nature Cell Biology (2016)

721 Citations

Activation of a Membrane-Bound Transcription Factor by Regulated Ubiquitin/Proteasome-Dependent Processing

Thorsten Hoppe;Kai Matuschewski;Michael Rape;Stephan Schlenker.
Cell (2000)

670 Citations

A Series of Ubiquitin Binding Factors Connects CDC48/p97 to Substrate Multiubiquitylation and Proteasomal Targeting

Holger Richly;Michael Rape;Sigurd Braun;Sebastian Rumpf.
Cell (2005)

621 Citations

Mechanism of Ubiquitin-Chain Formation by the human Anaphase-Promoting Complex

Lingyan Jin;Adam Williamson;Sudeep Banerjee;Isabelle Philipp.
Cell (2008)

590 Citations

Mobilization of Processed, Membrane-Tethered SPT23 Transcription Factor by CDC48UFD1/NPL4, a Ubiquitin-Selective Chaperone

Michael Rape;Thorsten Hoppe;Ingo Gorr;Marian Kalocay.
Cell (2001)

516 Citations

K11-Linked Polyubiquitination in Cell Cycle Control Revealed by a K11 Linkage-Specific Antibody

Marissa L. Matsumoto;Katherine E. Wickliffe;Ken C. Dong;Christine Yu.
Molecular Cell (2010)

419 Citations

Enhanced protein degradation by branched ubiquitin chains

Hermann-Josef Meyer;Michael Rape.
Cell (2014)

414 Citations

Role of the ubiquitin‐selective CDC48UFD1/NPL4 chaperone (segregase) in ERAD of OLE1 and other substrates

Sigurd Braun;Kai Matuschewski;Michael Rape;Sven Thoms;Sven Thoms.
The EMBO Journal (2002)

405 Citations

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