World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
81
Citations
26778
World Ranking
3838
National Ranking
1900

Research.com Recognitions

  • 2013 - Hellman Fellow

Overview

Daniel K. Nomura is affiliated with the University of California, Berkeley in the United States. Their research spans several fields within the life sciences, focusing mainly on biochemistry, genetics, molecular biology, and medicine.

Their body of work covers a range of subfields, including molecular biology, organic chemistry, oncology, immunology, and hematology. Throughout their career, the scientist has concentrated on several key topics, among which are:

  • Protein degradation and inhibitors
  • Ubiquitin and proteasome pathways
  • Click chemistry and applications
  • Peptidase inhibition and analysis
  • Multiple myeloma research and treatments
  • Computational drug discovery methods
  • Chemical synthesis and analysis

The scientist has published extensively, with notable recent papers that include:

  • Advances in covalent drug discovery (2022), published in Nature Reviews Drug Discovery
  • Deubiquitinase-targeting chimeras for targeted protein stabilization (2022), published in Nature Chemical Biology
  • Discovery of a Covalent FEM1B Recruiter for Targeted Protein Degradation Applications (2022), published in Journal of the American Chemical Society
  • Reimagining Druggability Using Chemoproteomic Platforms (2021), published in Accounts of Chemical Research
  • A Cellular Mechanism to Detect and Alleviate Reductive Stress (2020), published in Cell

Frequent collaborators in their research include Markus Schirle, Jeffrey M. McKenna, John A. Tallarico, Dustin Dovala, and Jessica N. Spradlin.

The scientist has contributed to multiple publication venues, with a significant number of works appearing in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • ACS Chemical Biology
  • Journal of the American Chemical Society
  • Cell chemical biology
  • ACS Central Science

In recognition of their research contributions, the scientist was awarded the Hellman Fellow in 2013.

Best Publications

  • The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis.

    Kirill Bersuker;Joseph M. Hendricks;Zhipeng Li;Leslie Magtanong

  • Monoacylglycerol Lipase Regulates a Fatty Acid Network that Promotes Cancer Pathogenesis

    Daniel K. Nomura;Jonathan Z. Long;Sherry Niessen;Heather S. Hoover

  • Exogenous Monounsaturated Fatty Acids Promote a Ferroptosis-Resistant Cell State.

    Leslie Magtanong;Pin-Joe Ko;Milton To;Jennifer Yinuo Cao

  • Endocannabinoid Hydrolysis Generates Brain Prostaglandins That Promote Neuroinflammation

    Daniel K. Nomura;Daniel K. Nomura;Bradley E. Morrison;Jacqueline L. Blankman;Jonathan Z. Long

  • Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system

    Joel E Schlosburg;Jacqueline L Blankman;Jonathan Z Long;Daniel K Nomura

  • Microglia dictate the impact of saturated fat consumption on hypothalamic inflammation and neuronal function.

    Martin Valdearcos;Megan M. Robblee;Daniel I. Benjamin;Daniel K. Nomura

  • DGAT1-Dependent Lipid Droplet Biogenesis Protects Mitochondrial Function during Starvation-Induced Autophagy

    Truc B. Nguyen;Sharon M. Louie;Joseph R. Daniele;Quan Tran

  • Inhibition of fatty acid oxidation as a therapy for MYC-overexpressing triple-negative breast cancer

    Roman Camarda;Alicia Y Zhou;Rebecca A Kohnz;Sanjeev Balakrishnan

  • Lysosomal cholesterol activates mTORC1 via an SLC38A9-Niemann-Pick C1 signaling complex

    Brian M. Castellano;Ashley M. Thelen;Ofer Moldavski;McKenna Feltes

  • Dual blockade of FAAH and MAGL identifies behavioral processes regulated by endocannabinoid crosstalk in vivo

    Jonathan Z. Long;Daniel K. Nomura;Robert E. Vann;D. Matthew Walentiny

  • Activity-based protein profiling for biochemical pathway discovery in cancer

    Daniel K. Nomura;Melissa M. Dix;Benjamin F. Cravatt

  • Harnessing the anti-cancer natural product nimbolide for targeted protein degradation

    Jessica N. Spradlin;Jessica N. Spradlin;Xirui Hu;Xirui Hu;Carl C. Ward;Carl C. Ward;Scott M. Brittain

  • Characterization of Monoacylglycerol Lipase Inhibition Reveals Differences in Central and Peripheral Endocannabinoid Metabolism

    Jonathan Z. Long;Daniel K. Nomura;Benjamin F. Cravatt

  • Mechanistic and Pharmacological Characterization of PF-04457845: A Highly Potent and Selective Fatty Acid Amide Hydrolase Inhibitor That Reduces Inflammatory and Noninflammatory Pain

    Kay Ahn;Sarah E. Smith;Marya B. Liimatta;David Beidler

  • A Proximity Labeling Strategy Provides Insights into the Composition and Dynamics of Lipid Droplet Proteomes

    Kirill Bersuker;Clark W.H. Peterson;Milton To;Steffen J. Sahl

  • Effective breast cancer combination therapy targeting BACH1 and mitochondrial metabolism.

    Jiyoung Lee;Ali E. Yesilkanal;Joseph P. Wynne;Casey Frankenberger

  • Monoacylglycerol lipase exerts dual control over endocannabinoid and fatty acid pathways to support prostate cancer

    Daniel K. Nomura;Donald P. Lombardi;Jae Won Chang;Sherry Niessen

  • Suppressing fatty acid uptake has therapeutic effects in preclinical models of prostate cancer

    Matthew J. Watt;Matthew J. Watt;Ashlee K. Clark;Luke A. Selth;Vanessa R. Haynes;Vanessa R. Haynes

  • Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications.

    Carl C. Ward;Jordan I. Kleinman;Scott M. Brittain;Scott M. Brittain;Patrick S. Lee;Patrick S. Lee

  • Mitochondrial DNA Replication Defects Disturb Cellular dNTP Pools and Remodel One-Carbon Metabolism

    Joni Nikkanen;Saara Forsström;Liliya Euro;Ilse Paetau

Frequent Co-Authors

Benjamin F. Cravatt
Benjamin F. Cravatt Scripps Research Institute
Markus Schirle
Markus Schirle Novartis (Switzerland)
John E. Casida
John E. Casida University of California, Berkeley
Andrei Goga
Andrei Goga University of California, San Francisco
Roberto Zoncu
Roberto Zoncu University of California, Berkeley
Aron H. Lichtman
Aron H. Lichtman Virginia Commonwealth University
Jamie H. D. Cate
Jamie H. D. Cate University of California, Berkeley
Michael Rape
Michael Rape University of California, Berkeley
Shingo Kajimura
Shingo Kajimura Beth Israel Deaconess Medical Center
Andreas Stahl
Andreas Stahl University of California, Berkeley

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