World's Best Scientists 2026 revealed!

D-Index & Metrics

Microbiology

D-Index
56
Citations
10419
World Ranking
3717
National Ranking
1456

Overview

Photini Sinnis is affiliated with Johns Hopkins University in the United States. Their research primarily focuses on malaria and mosquito-borne diseases, contributing to fields such as medicine, immunology, microbiology, public health, and parasitology.

Their areas of study include:

  • Malaria Research and Control
  • Mosquito-borne diseases and control
  • Invertebrate Immune Response Mechanisms
  • Parasites and Host Interactions
  • Viral Infections and Vectors
  • Complement system in diseases
  • Insect Pest Control Strategies

Frequent coauthors collaborating with Sinnis include:

  • Sachie Kanatani
  • Abhai K. Tripathi
  • Godfree Mlambo
  • Melanie J. Shears
  • David A. Fidock

Sinnis has published extensively in several recognized venues. The most frequent publication platforms are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Trends in Parasitology
  • Journal of Visualized Experiments
  • Proceedings of the National Academy of Sciences

Recent papers by Photini Sinnis demonstrate the scope of their research:

  • "When Is a Plasmodium-Infected Mosquito an Infectious Mosquito?", 2020, Trends in Parasitology
  • "Experimental determination of the force of malaria infection reveals a non-linear relationship to mosquito sporozoite loads", 2020, PLoS Pathogens
  • "Plasmodium falciparum Gametocyte Culture and Mosquito Infection Through Artificial Membrane Feeding", 2020, Journal of Visualized Experiments
  • "A G358S mutation in the Plasmodium falciparum Na+ pump PfATP4 confers clinically-relevant resistance to cipargamin", 2022, Nature Communications
  • "Transcriptional heterogeneity and tightly regulated changes in gene expression during Plasmodium berghei sporozoite development", 2021, Proceedings of the National Academy of Sciences

Photini Sinnis's work spans interdisciplinary topics within immunology and infectious diseases, emphasizing vector biology and the molecular mechanisms of parasite transmission. Their research outputs contribute to understanding the complexities of malaria infection and mosquito vector dynamics.

Best Publications

  • Malaria circumsporozoite protein binds to heparan sulfate proteoglycans associated with the surface membrane of hepatocytes.

    Ute Frevert;Photini Sinnis;Carla Cerami;Wayne Shreffler

  • The basolateral domain of the hepatocyte plasma membrane bears receptors for the circumsporozoite protein of plasmodium falciparum sporozoites

    Carla Cerami;Ute Frevert;Photini Sinnis;Bela Takacs

  • The malaria circumsporozoite protein has two functional domains, each with distinct roles as sporozoites journey from mosquito to mammalian host

    Alida Coppi;Ramya Natarajan;Gabriele Pradel;Brandy L. Bennett

  • The fatty acid biosynthesis enzyme FabI plays a key role in the development of liver-stage malarial parasites.

    Min Yu;T. R.Santha Kumar;T. R.Santha Kumar;Louis J. Nkrumah;Alida Coppi

  • Heparan Sulfate Proteoglycans Provide a Signal to Plasmodium Sporozoites to Stop Migrating and Productively Invade Host Cells

    Alida Coppi;Rita Tewari;Joseph R. Bishop;Brandy L. Bennett

  • Plasmodium sporozoites trickle out of the injection site.

    Lucy Megumi Yamauchi;Alida Coppi;Georges Snounou;Photini Sinnis

  • A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite

    Neville K. Kisalu;Azza H. Idris;Connor Weidle;Yevel Flores-Garcia

  • Quantitative Dynamics of Plasmodium yoelii Sporozoite Transmission by Infected Anopheline Mosquitoes

    Darcy L. Medica;Photini Sinnis

  • The Plasmodium circumsporozoite protein is proteolytically processed during cell invasion

    Alida Coppi;Consuelo Pinzon-Ortiz;Christina Hutter;Photini Sinnis

  • Interrogating the Plasmodium Sporozoite Surface: Identification of Surface-Exposed Proteins and Demonstration of Glycosylation on CSP and TRAP by Mass Spectrometry-Based Proteomics.

    Kristian E. Swearingen;Scott E. Lindner;Scott E. Lindner;Lirong Shi;Melanie J. Shears

  • Malaria in India: The Center for the Study of Complex Malaria in India

    Aparup Das;Anupkumar R. Anvikar;Lauren J. Cator;Ramesh C. Dhiman

  • The Plasmodium circumsporozoite protein is involved in mosquito salivary gland invasion by sporozoites.

    Joon Mo Myung;Patricia Marshall;Photini Sinnis

  • Proteasome Inhibitors Block Development of Plasmodium spp.

    Soren M. Gantt;Joon Mo Myung;Marcelo Ribeiro da Silva Briones;Wei Dong Li

  • Total and putative surface proteomics of malaria parasite salivary gland sporozoites

    Scott E. Lindner;Kristian E. Swearingen;Anke Harupa;Anke Harupa;Ashley M. Vaughan

  • Antimalarial Activity of Allicin, a Biologically Active Compound from Garlic Cloves

    Alida Coppi;Melissa Cabinian;David Mirelman;Photini Sinnis

  • Structural and functional properties of region II-plus of the malaria circumsporozoite protein.

    Photini Sinnis;Pedro Clavijo;David Fenyö;Brian T. Chait

  • The binding of the circumsporozoite protein to cell surface heparan sulfate proteoglycans is required for plasmodium sporozoite attachment to target cells.

    Consuelo Pinzon-Ortiz;Jennifer Friedman;Jeffrey Esko;Photini Sinnis

  • Longitudinal analysis of Plasmodium sporozoite motility in the dermis reveals component of blood vessel recognition

    Christine S. Hopp;Kevin Chiou;Daniel R.T. Ragheb;Ahmed M. Salman

  • Plasmodium sporozoite-host interactions from the dermis to the hepatocyte.

    Ijeoma Ejigiri;Photini Sinnis

  • Shedding of TRAP by a Rhomboid Protease from the Malaria Sporozoite Surface Is Essential for Gliding Motility and Sporozoite Infectivity

    Ijeoma Ejigiri;Daniel R. T. Ragheb;Paco Pino;Alida Coppi

  • Transcriptomics and proteomics reveal two waves of translational repression during the maturation of malaria parasite sporozoites.

    Scott E. Lindner;Kristian E. Swearingen;Melanie J. Shears;Melanie J. Shears;Michael P. Walker

Frequent Co-Authors

Victor Nussenzweig
Victor Nussenzweig New York University
Fidel P Zavala
Fidel P Zavala Johns Hopkins University
David A. Fidock
David A. Fidock Columbia University
Stefan H. I. Kappe
Stefan H. I. Kappe University of Washington
Robert L. Moritz
Robert L. Moritz Institute for Systems Biology
Rita Tewari
Rita Tewari University of Nottingham
François Nosten
François Nosten MORU Mahidol Oxford Tropical Medicine Research Unit
Laurent Rénia
Laurent Rénia Nanyang Technological University
Volker Heussler
Volker Heussler University of Bern
Georges Snounou
Georges Snounou Inserm : Institut national de la santé et de la recherche médicale

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying Microbiology in the USA opens doors to a variety of related online degrees and career pathways that complement the scientific foundation of microbiology. For example, pursuing certifications like the ccls certification can lead to specialized roles that blend science with patient care and support in healthcare settings.

For individuals seeking flexible education options, finding the best degree for felons is a critical consideration. Many online microbiology and allied health programs are accessible to non-traditional students, providing valuable second chances and robust career prospects.

Health sciences also overlap with microbiology, offering careers such as a Functional Medicine Nurse Practitioner. Exploring the functional medicine np salary can help students understand the financial landscape and opportunities within this emerging field.

Additionally, the healthcare industry offers career paths like medical coding, where certifications like the Certified Professional Coder (CPC) are essential. Learning about the cpc medical coding salary provides insight into a rewarding and stable job market related to healthcare administration.

Best Scientists Citing Photini Sinnis

Trending Scientists