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Geoffrey I. McFadden

Geoffrey I. McFadden

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Biology and Biochemistry
Australia
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
92
Citations
31560
World Ranking
2209
National Ranking
51

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Australia Leader Award

Overview

Geoffrey I. McFadden is a researcher affiliated with the University of Melbourne in Australia. Their work primarily focuses on medicine and immunology and microbiology, contributing to 51 and 35 publications respectively in these fields. Specific subfields of study include public health, environmental and occupational health, immunology, parasitology, ecology, and molecular biology.

Their research covers various topics, notably malaria research and control, mosquito-borne diseases and control, immune cell function and interaction, immunotherapy and immune responses, coral and marine ecosystems studies, Toxoplasma gondii research studies, and Trypanosoma species research and implications.

Geoffrey I. McFadden has published extensively in scientific journals, with frequent venues including bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Cell Reports, Journal of Eukaryotic Microbiology, and the International Journal for Parasitology.

Among their recent papers are:

  • Mechanisms and targets of Fcγ-receptor mediated immunity to malaria sporozoites, 2021, Nature Communications
  • A Natural Peptide Antigen within the Plasmodium Ribosomal Protein RPL6 Confers Liver TRM Cell-Mediated Immunity against Malaria in Mice, 2020, Cell Host & Microbe
  • Division and Adaptation to Host Environment of Apicomplexan Parasites Depend on Apicoplast Lipid Metabolic Plasticity and Host Organelle Remodeling, 2020, Cell Reports
  • mRNA vaccine against malaria tailored for liver-resident memory T cells, 2023, Nature Immunology
  • Glycolipid-peptide vaccination induces liver-resident memory CD8 + T cells that protect against rodent malaria, 2020, Science Immunology

The researcher often collaborates with several frequent co-authors, including C.D. Goodman, Anton Cozijnsen, William R. Heath, Vanessa Mollard, and Daniel Fernandez-Ruiz.

Best Publications

  • Genome sequence of the human malaria parasite Plasmodium falciparum

    Malcolm J. Gardner;Neil Hall;Eula Fung;Owen White

  • Nuclear-encoded proteins target to the plastid in Toxoplasma gondii and Plasmodium falciparum

    Ross F. Waller;Patrick J. Keeling;Robert G. K. Donald;Boris Striepen

  • Tropical infectious diseases: metabolic maps and functions of the Plasmodium falciparum apicoplast.

    Stuart A. Ralph;Giel G. van Dooren;Ross F. Waller;Michael J. Crawford

  • Plastid in human parasites

    Geoffrey I. McFadden;Michael E. Reith;Janet Munholland;Naomi Lang-Unnasch

  • Protein trafficking to the plastid of Plasmodium falciparum is via the secretory pathway

    Ross F. Waller;Michael B. Reed;Alan F. Cowman;Geoffrey I. McFadden

  • Functional Profiling of a Plasmodium Genome Reveals an Abundance of Essential Genes

    Ellen Bushell;Ana Rita Gomes;Theo Sanderson;Burcu Anar

  • Dissecting apicoplast targeting in the malaria parasite Plasmodium falciparum

    Bernardo J. Foth;Stuart A. Ralph;Christopher J. Tonkin;Nicole S. Struck

  • Localization of organellar proteins in Plasmodium falciparum using a novel set of transfection vectors and a new immunofluorescence fixation method

    Christopher J. Tonkin;Giel G. van Dooren;Timothy P. Spurck;Nicole S. Struck

  • Primary and secondary endosymbiosis and the origin of plastids

    Geoffrey Ian McFadden

  • Liver-Resident Memory CD8 + T Cells Form a Front-Line Defense against Malaria Liver-Stage Infection.

    Daniel Fernandez-Ruiz;Wei Yi Ng;Wei Yi Ng;Lauren E Holz;Joel Z Ma

  • Algal genomes reveal evolutionary mosaicism and the fate of nucleomorphs.

    Bruce A. Curtis;Goro Tanifuji;Goro Tanifuji;Fabien Burki;Ansgar Gruber;Ansgar Gruber

  • The evolution, metabolism and functions of the apicoplast

    Liting Lim;Geoffrey Ian McFadden

  • Trafficking and assembly of the cytoadherence complex in Plasmodium falciparum-infected human erythrocytes.

    Mark E. Wickham;Melanie Rug;Stuart A. Ralph;Nectarios Klonis

  • Phenotypic variation of Plasmodium falciparum merozoite proteins directs receptor targeting for invasion of human erythrocytes.

    Manoj T. Duraisingh;Tony Triglia;Stuart A. Ralph;Julian C. Rayner

  • Metabolic maps and functions of the Plasmodium mitochondrion

    Giel G. van Dooren;Luciana M. Stimmler;Geoffrey I. McFadden

  • Development of the endoplasmic reticulum, mitochondrion and apicoplast during the asexual life cycle of Plasmodium falciparum

    Giel G. van Dooren;Matthias Marti;Christopher J. Tonkin;Luciana M. Stimmler

  • Apicomplexan plastids as drug targets.

    Geoffrey I. McFadden;David S. Roos

  • Use of Hepes buffer for microalgal culture media and fixation for electron microscopy

    G. I. McFadden;M. Melkonian

  • Evolution: red algal genome affirms a common origin of all plastids.

    Geoffrey I McFadden;Giel G van Dooren

  • The effects of anti-bacterials on the malaria parasite Plasmodium falciparum.

    Christopher Dean Goodman;Vanessa Su;Geoffrey I. McFadden

Frequent Co-Authors

Ross F. Waller
Ross F. Waller University of Cambridge
Paul R. Gilson
Paul R. Gilson Burnet Institute
Stuart A. Ralph
Stuart A. Ralph University of Melbourne
William R. Heath
William R. Heath University of Melbourne
Brendan S. Crabb
Brendan S. Crabb Monash University
Christopher J. Tonkin
Christopher J. Tonkin Walter and Eliza Hall Institute of Medical Research
Alan F. Cowman
Alan F. Cowman Walter and Eliza Hall Institute of Medical Research
Jake Baum
Jake Baum University of New South Wales
James G. Beeson
James G. Beeson Burnet Institute
Patrick J. Keeling
Patrick J. Keeling University of British Columbia

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