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Biology and Biochemistry

D-Index
57
Citations
19237
World Ranking
13553
National Ranking
377

Overview

Stuart A. Ralph is affiliated with the University of Melbourne in Australia. Their research spans multiple areas within medicine and biochemistry, genetics, and molecular biology, prominently focusing on parasitology and infectious diseases.

Their scientific contributions include recent papers published in notable venues such as Trends in Parasitology, mSystems, Nature Communications, PLoS Pathogens, and mBio. Selected recent publications include:

  • K13, the Cytostome, and Artemisinin Resistance (2020) in Trends in Parasitology
  • Direct Nanopore Sequencing of mRNA Reveals Landscape of Transcript Isoforms in Apicomplexan Parasites (2021) in mSystems
  • PfCERLI1 is a conserved rhoptry associated protein essential for Plasmodium falciparum merozoite invasion of erythrocytes (2020) in Nature Communications
  • Chromosome-level genome of Schistosoma haematobium underpins genome-wide explorations of molecular variation (2022) in PLoS Pathogens
  • Functional Characterization of the m 6 A-Dependent Translational Modulator PfYTH.2 in the Human Malaria Parasite (2021) in mBio

The main fields of study where Stuart A. Ralph has contributed include Medicine and Biochemistry, Genetics and Molecular Biology. Within these, their subfields prominently feature Molecular Biology, Public Health, Environmental and Occupational Health, Parasitology, Epidemiology, and Immunology.

The research topics they have extensively worked on cover an array of infectious diseases and molecular mechanisms. Key areas of focus include:

  • Malaria Research and Control
  • Mosquito-borne diseases and control
  • RNA modifications and cancer
  • RNA and protein synthesis mechanisms
  • Research on Leishmaniasis Studies
  • Toxoplasma gondii Research Studies
  • RNA Research and Splicing

Stuart A. Ralph collaborates frequently with a network of colleagues including Christopher J. Tonkin, Emma McHugh, Michaela S. Bulloch, Darren J. Creek, and Leann Tilley. Their repeated partnerships indicate active involvement in collaborative research efforts.

Regarding publication venues, their work appears frequently in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Trends in Parasitology
  • PLoS Pathogens
  • mSystems
  • Nature Communications

Best Publications

  • Genome sequence of the human malaria parasite Plasmodium falciparum

    Malcolm J. Gardner;Neil Hall;Eula Fung;Owen White

  • Comparative genomics of the neglected human malaria parasite Plasmodium vivax

    Jane M. Carlton;Jane M. Carlton;John H. Adams;Joana C. Silva;Shelby L. Bidwell

  • Tropical infectious diseases: metabolic maps and functions of the Plasmodium falciparum apicoplast.

    Stuart A. Ralph;Giel G. van Dooren;Ross F. Waller;Michael J. Crawford

  • Telomeric Heterochromatin Propagation and Histone Acetylation Control Mutually Exclusive Expression of Antigenic Variation Genes in Malaria Parasites

    Lucio H. Freitas-Junior;Rosaura Hernandez-Rivas;Stuart A. Ralph;Dvorak Montiel-Condado

  • Dissecting apicoplast targeting in the malaria parasite Plasmodium falciparum

    Bernardo J. Foth;Stuart A. Ralph;Christopher J. Tonkin;Nicole S. Struck

  • Super-Resolution Dissection of Coordinated Events during Malaria Parasite Invasion of the Human Erythrocyte

    David T Riglar;Dave Richard;Danny W Wilson;Michelle J. Boyle;Michelle J. Boyle

  • Trafficking and assembly of the cytoadherence complex in Plasmodium falciparum-infected human erythrocytes.

    Mark E. Wickham;Melanie Rug;Stuart A. Ralph;Nectarios Klonis

  • Genome sequence of Theileria parva, a bovine pathogen that transforms lymphocytes.

    Malcolm J. Gardner;Richard Bishop;Trushar Shah;Etienne P. de Villiers

  • Artemisinin Action and Resistance in Plasmodium falciparum.

    Leann Tilley;Judith Straimer;Nina F. Gnädig;Stuart A. Ralph

  • Genomic-scale prioritization of drug targets: the TDR Targets database

    Fernán Agüero;Bissan Al-Lazikani;Martin Aslett;Matthew Berriman

  • ISOLATION OF VIABLE PLASMODIUM FALCIPARUM MEROZOITES TO DEFINE ERYTHROCYTE INVASION EVENTS AND ADVANCE VACCINE AND DRUG DEVELOPMENT

    Michelle J Boyle;Danny W Wilson;Jack S Richards;David T Riglar

  • Phenotypic variation of Plasmodium falciparum merozoite proteins directs receptor targeting for invasion of human erythrocytes.

    Manoj T. Duraisingh;Tony Triglia;Stuart A. Ralph;Julian C. Rayner

  • Reticulocyte-binding protein homologue 5 – An essential adhesin involved in invasion of human erythrocytes by Plasmodium falciparum

    Jake Baum;Lin Chen;Julie Healer;Sash Lopaticki

  • Interaction between Plasmodium falciparum apical membrane antigen 1 and the rhoptry neck protein complex defines a key step in the erythrocyte invasion process of malaria parasites

    Dave Richard;Christopher A. MacRaild;David T. Riglar;Jo-Anne Chan

  • Plasmodium falciparum Heterochromatin Protein 1 Marks Genomic Loci Linked to Phenotypic Variation of Exported Virulence Factors

    Christian Flueck;Richard Bartfai;Jennifer Volz;Igor Niederwieser

  • Sir2 paralogues cooperate to regulate virulence genes and antigenic variation in Plasmodium falciparum.

    Christopher J Tonkin;Céline K Carret;Céline K Carret;Manoj T Duraisingh;Manoj T Duraisingh;Till S Voss

  • Deciphering apicoplast targeting signals--feature extraction from nuclear-encoded precursors of Plasmodium falciparum apicoplast proteins.

    Jochen Zuegge;Stuart Ralph;Michael Schmuker;Geoffrey I McFadden

  • Artemisinin kills malaria parasites by damaging proteins and inhibiting the proteasome.

    Jessica L Bridgford;Stanley C Xie;Simon A Cobbold;Charisse Flerida A Pasaje

  • The apicoplast as an antimalarial drug target.

    Stuart A. Ralph;Marthe C. D'Ombrain;Geoffrey I. McFadden

  • Antigenic variation in Plasmodium falciparum is associated with movement of var loci between subnuclear locations

    Stuart A. Ralph;Christine Scheidig-Benatar;Artur Scherf

Frequent Co-Authors

Alan F. Cowman
Alan F. Cowman Walter and Eliza Hall Institute of Medical Research
Jake Baum
Jake Baum University of New South Wales
Geoffrey I. McFadden
Geoffrey I. McFadden University of Melbourne
Christopher J. Tonkin
Christopher J. Tonkin Walter and Eliza Hall Institute of Medical Research
David S. Roos
David S. Roos University of Pennsylvania
Malcolm J. McConville
Malcolm J. McConville University of Melbourne
Jonathan B. Baell
Jonathan B. Baell Monash University
Artur Scherf
Artur Scherf Institut Pasteur
Vicky M. Avery
Vicky M. Avery Griffith University

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