Diane P. Hanger

Overview

Best Publications

• Tau phosphorylation: the therapeutic challenge for neurodegenerative disease.

  Diane P. Hanger;Brian H. Anderton;Wendy Noble

  1148
  Citations

• Roles of tau protein in health and disease.

  Tong Guo;Wendy Jane Noble;Diane Pamela Hanger

  1020
  Citations

• Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: generation of paired helical filament epitopes and neuronal localisation of the kinase.

  Diane P. Hanger;Kenneth Hughes;James R. Woodgett;Jean-Pierre Brion

  928
  Citations

• Physiological release of endogenous tau is stimulated by neuronal activity.

  Amy M Pooler;Emma C Phillips;Dawn H W Lau;Wendy Noble

  690
  Citations

• Alzheimer's disease-like phosphorylation of the microtubule-associated protein tau by glycogen synthase kinase-3 in transfected mammalian cells

  S Lovestone;C H Reynolds;D Latimer;Davis

  644
  Citations

• Novel Phosphorylation Sites in Tau from Alzheimer Brain Support a Role for Casein Kinase 1 in Disease Pathogenesis

  Diane P. Hanger;Helen L. Byers;Selina Wray;Kit-Yi Leung

  527
  Citations

• The importance of tau phosphorylation for neurodegenerative diseases.

  Wendy Noble;Diane P. Hanger;Christopher C. J. Miller;Simon Lovestone

  505
  Citations

• New phosphorylation sites identified in hyperphosphorylated tau (paired helical filament-tau) from Alzheimer's disease brain using nanoelectrospray mass spectrometry.

  Diane P. Hanger;Joanna C. Betts;Thérèse L. F. Loviny;Walter P. Blackstock

  476
  Citations

• Astrocytes are important mediators of Aβ-induced neurotoxicity and tau phosphorylation in primary culture

  Claire Garwood;Amy Pooler;J. Atherton;Diane Hanger

  417
  Citations

• α-Synuclein binds to the ER–mitochondria tethering protein VAPB to disrupt Ca 2+ homeostasis and mitochondrial ATP production

  Sébastien Paillusson;Patricia Gomez-Suaga;Radu Stoica;Daniel Little

  368
  Citations

• The ER-Mitochondria Tethering Complex VAPB-PTPIP51 Regulates Autophagy

  Patricia Gomez-Suaga;Sebastien Paillusson;Radu Stoica;Wendy Noble

  345
  Citations

• Phosphorylation Regulates Tau Interactions with Src Homology 3 Domains of Phosphatidylinositol 3-Kinase, Phospholipase Cγ1, Grb2, and Src Family Kinases

  C. Hugh Reynolds;Claire J. Garwood;Selina Wray;Caroline Price

  283
  Citations

• ALS/FTD-associated FUS activates GSK-3β to disrupt the VAPB–PTPIP51 interaction and ER–mitochondria associations

  Radu Stoica;Sébastien Paillusson;Patricia Gomez‐Suaga;Jacqueline C Mitchell

  251
  Citations

• A role for tau at the synapse in Alzheimer's disease pathogenesis.

  Amy M Pooler;Wendy Noble;Diane P Hanger

  248
  Citations

• Tyrosine 394 is phosphorylated in Alzheimer's paired helical filament tau and in fetal tau with c-Abl as the candidate tyrosine kinase.

  Pascal Derkinderen;Timothy M. E. Scales;Diane P. Hanger;Kit-Yi Leung

  234
  Citations

• Tau phosphorylation affects its axonal transport and degradation

  Teresa Rodríguez-Martín;Inmaculada Cuchillo-Ibáñez;Wendy Noble;Fanon Nyenya

  228
  Citations

• Induction of neuronal death by alpha-synuclein.

  Anirban R. Saha;Natalia N. Ninkina;Diane P. Hanger;Brian H. Anderton

  226
  Citations

• Tau in Alzheimer neurofibrillary tangles. N- and C-terminal regions are differentially associated with paired helical filaments and the location of a putative abnormal phosphorylation site.

  J.-P. Brion;D. P. Hanger;M. T.K Bruce;A.-M. Couck

  224
  Citations

• Parkinson's disease alpha-synuclein mutations exhibit defective axonal transport in cultured neurons

  Anirban R. Saha;Josephine Hill;Michelle A. Utton;Ayodeji A. Asuni

  222
  Citations

• Pathological inclusion bodies in tauopathies contain distinct complements of tau with three or four microtubule-binding repeat domains as demonstrated by new specific monoclonal antibodies.

  R de Silva;T Lashley;G Gibb;Diane Hanger

  200
  Citations