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Vladimir L. Buchman

Vladimir L. Buchman

D-Index & Metrics

Biology and Biochemistry

D-Index
53
Citations
12401
World Ranking
16023
National Ranking
1267

Overview

Vladimir L. Buchman is affiliated with Cardiff University in the United Kingdom and has contributed extensively to research in medicine and biochemistry, genetics, and molecular biology. Their work primarily intersects with neurology, molecular biology, and cellular and molecular neuroscience, reflecting a broad engagement in the physiological and cellular mechanisms underlying neurological conditions.

The scientist's research portfolio covers several specialized topics including:

  • Parkinson's Disease Mechanisms and Treatments
  • Alzheimer's disease research and treatments
  • Neurological disorders and treatments
  • Amyotrophic Lateral Sclerosis Research
  • Nuclear Receptors and Signaling
  • Neuroscience and Neuropharmacology Research
  • RNA Research and Splicing

Notable recent publications demonstrate a focus on molecular and cellular processes in neurological diseases. These include:

  • "Long non-coding RNA Neat1 regulates adaptive behavioural response to stress in mice" (2020), published in Translational Psychiatry
  • "Single residue modulators of amyloid formation in the N-terminal P1-region of α-synuclein" (2022), published in Nature Communications
  • "Synaptic vesicle binding of α-synuclein is modulated by β- and γ-synucleins" (2022), published in Cell Reports
  • "Alterations in the nigrostriatal system following conditional inactivation of α-synuclein in neurons of adult and aging mice" (2020), published in Neurobiology of Aging
  • "ALS-linked cytoplasmic FUS assemblies are compositionally different from physiological stress granules and sequester hnRNPA3, a novel modifier of FUS toxicity" (2021), published in Neurobiology of Disease

Frequently publishing in venues such as bioRxiv (Cold Spring Harbor Laboratory), Cell Reports, Molecular Brain, Molecules, and Research Square, Vladimir L. Buchman maintains a diverse publishing profile across several established scientific journals.

The scientist collaborates with multiple researchers, including frequent coauthors:

  • Natalia Ninkina
  • Kirill Chaprov
  • Michail S. Kukharsky
  • Haiyan An
  • Tatyana A. Shelkovnikova

Best Publications

  • α-Synuclein promotes SNARE-complex assembly in vivo and in vitro

    Jacqueline Burre;Manu Sharma;Theodoros Tsetsenis;Vladimir L. Buchman

  • GDNF is an age-specific survival factor for sensory and autonomic neurons

    Anna Buj-Bello;Vladimir L. Buchman;Antony Horton;Arnon Rosenthal

  • Different neurotrophins are expressed and act in a developmental sequence to promote the survival of embryonic sensory neurons

    Vladimir L. Buchman;Alun M. Davies

  • Neurturin responsiveness requires a GPI-linked receptor and the Ret receptor tyrosine kinase.

    Anna Buj-Bello;Jimi Adu;Luzia G. P. Piñón;Antony Horton

  • A variation in the structure of the protein-coding region of the human p53 gene

    V.L. Buchman;P.M. Chumakov;N.N. Ninkina;O.P. Samarina

  • Part II: α-synuclein and its molecular pathophysiological role in neurodegenerative disease

    Kumlesh K. Dev;Katja Hofele;Samuel Barbieri;Vladimir L. Buchman

  • αβγ-Synuclein triple knockout mice reveal age-dependent neuronal dysfunction

    Becket Greten-Harrison;Manuela Polydoro;Megumi Morimoto-Tomita;Ling Diao

  • α-Synuclein and dopamine at the crossroads of Parkinson's disease

    Lara Lourenço Venda;Stephanie J. Cragg;Vladimir L. Buchman;Richard Wade-Martins

  • Functional Alterations to the Nigrostriatal System in Mice Lacking All Three Members of the Synuclein Family

    S Anwar;O Peters;S Millership;N Ninkina

  • Persyn, a Member of the Synuclein Family, Has a Distinct Pattern of Expression in the Developing Nervous System

    Vladimir L. Buchman;Hamish J. A. Hunter;Luzia G. P. Pinõn;Jane Thompson

  • Induction of neuronal death by alpha-synuclein.

    Anirban R. Saha;Natalia N. Ninkina;Diane P. Hanger;Brian H. Anderton

  • Myelination transition zone astrocytes are constitutively phagocytic and have synuclein dependent reactivity in glaucoma

    Judy V. Nguyen;Ileana Soto;Keun Young Kim;Eric A. Bushong

  • Parkinson's disease alpha-synuclein mutations exhibit defective axonal transport in cultured neurons

    Anirban R. Saha;Josephine Hill;Michelle A. Utton;Ayodeji A. Asuni

  • GFRα-4 and the tyrosine kinase Ret form a functional receptor complex for persephin

    Yasushi Enokido;Fred de Sauvage;Jo-Anne Hongo;Natalia Ninkina

  • Autoantibodies to alpha‐synuclein in inherited Parkinson’s disease

    Katerina K. Papachroni;Natalia Ninkina;Angeliki Papapanagiotou;Georgios M. Hadjigeorgiou

  • Role of STAT3 and PI 3-kinase/Akt in mediating the survival actions of cytokines on sensory neurons.

    Tonino Alonzi;Gayle Middleton;Sean Wyatt;Vladimir Buchman

  • Negative regulation of PI 3-kinase by Ruk, a novel adaptor protein

    Ivan Gout;Gayle Middleton;Jimi Adu;Natalia N. Ninkina;Natalia N. Ninkina

  • Increased striatal dopamine release and hyperdopaminergic‐like behaviour in mice lacking both alpha‐synuclein and gamma‐synuclein

    Steven L. Senior;Natalia Ninkina;Robert Deacon;David Bannerman

  • Developmental loss and resistance to MPTP toxicity of dopaminergic neurones in substantia nigra pars compacta of γ-synuclein, α-synuclein and double α/γ-synuclein null mutant mice

    Darren C. Robertson;Oliver Schmidt;Natalia Ninkina;Paul A. Jones

  • Monomeric Alpha-Synuclein Exerts a Physiological Role on Brain ATP Synthase.

    Marthe H.R. Ludtmann;Plamena R. Angelova;Natalia N. Ninkina;Sonia Gandhi

Frequent Co-Authors

Alun M. Davies
Alun M. Davies Cardiff University
Ivan Gout
Ivan Gout University College London
Diane P. Hanger
Diane P. Hanger King's College London
Brian H. Anderton
Brian H. Anderton King's College London
Stephanie J. Cragg
Stephanie J. Cragg University of Oxford
Maria Grazia Spillantini
Maria Grazia Spillantini University of Cambridge
Pamela J. Shaw
Pamela J. Shaw University of Sheffield
Richard Wade-Martins
Richard Wade-Martins University of Oxford
Alexander V. Gourine
Alexander V. Gourine University College London
John Powell
John Powell King's College London

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