World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
95
Citations
33434
World Ranking
1900
National Ranking
1046

Overview

Benoit I. Giasson is affiliated with the University of Florida in the United States. Their research primarily focuses on the fields of Medicine and Neuroscience, with a significant number of publications dedicated to these areas. Within these broad fields, their subfields of study include Neurology, Physiology, Molecular Biology, Cellular and Molecular Neuroscience, and Psychiatry and Mental Health.

The main topics addressed in their work cover a range of neurological diseases and mechanisms, including:

  • Alzheimer's disease research and treatments
  • Parkinson's Disease Mechanisms and Treatments
  • Prion Diseases and Protein Misfolding
  • Neurological disorders and treatments
  • Nerve injury and regeneration
  • Neurological diseases and metabolism
  • Neuroinflammation and Neurodegeneration Mechanisms

The scientist has published extensively in several scientific journals. Frequent publication venues include:

  • Acta Neuropathologica Communications
  • Brain Communications
  • npj Parkinson s Disease
  • Neuroscience Letters
  • Molecular Neurodegeneration

Recent notable papers authored or co-authored by Benoit I. Giasson cover a variety of relevant topics and were published during 2020 and 2021. These include:

  • "Don't Phos Over Tau": recent developments in clinical biomarkers and therapies targeting tau phosphorylation in Alzheimer's disease and other tauopathies, 2021, Molecular Neurodegeneration
  • The emerging role of α-synuclein truncation in aggregation and disease, 2020, Journal of Biological Chemistry
  • Tau Ser208 phosphorylation promotes aggregation and reveals neuropathologic diversity in Alzheimer's disease and other tauopathies, 2020, Acta Neuropathologica Communications
  • Determinants of seeding and spreading of α-synuclein pathology in the brain, 2020, Science Advances
  • Multiple system atrophy-associated oligodendroglial protein p25α stimulates formation of novel α-synuclein strain with enhanced neurodegenerative potential, 2021, Acta Neuropathologica

Benoit I. Giasson collaborates frequently with several co-authors who contribute consistently to their research projects. These collaborators include:

  • Stefan Prokop
  • Zachary A. Sorrentino
  • Kimberly-Marie M. Gorion
  • Yuxing Xia
  • Brach M. Bell

Best Publications

  • Oxidative Damage Linked to Neurodegeneration by Selective α-Synuclein Nitration in Synucleinopathy Lesions

    Benoit I. Giasson;John E. Duda;Ian V. J. Murray;Qiping Chen

  • Neuronal α-Synucleinopathy with Severe Movement Disorder in Mice Expressing A53T Human α-Synuclein

    Benoit I. Giasson;John E. Duda;John E. Duda;Shawn M. Quinn;Bin Zhang

  • A Hydrophobic Stretch of 12 Amino Acid Residues in the Middle of α-Synuclein Is Essential for Filament Assembly

    Benoit I. Giasson;Ian V.J. Murray;John Q. Trojanowski;Virginia M.-Y. Lee

  • Initiation and synergistic fibrillization of tau and alpha-synuclein.

    Benoit I. Giasson;Mark S. Forman;Mark S. Forman;Makoto Higuchi;Makoto Higuchi;Lawrence I. Golbe;Lawrence I. Golbe

  • Glial cytoplasmic inclusions in white matter oligodendrocytes of multiple system atrophy brains contain insoluble α‐synuclein

    Pang-hsien Tu;James E. Galvin;James E. Galvin;Minami Baba;Benoit Giasson

  • Dityrosine cross-linking promotes formation of stable alpha -synuclein polymers. Implication of nitrative and oxidative stress in the pathogenesis of neurodegenerative synucleinopathies.

    José M. Souza;José M. Souza;Benoit I. Giasson;Qiping Chen;Virginia M.-Y. Lee

  • Mutant and wild type human alpha-synucleins assemble into elongated filaments with distinct morphologies in vitro.

    Benoit I. Giasson;Kunihiro Uryu;John Q. Trojanowski;Virginia M.-Y Lee

  • Lewy Bodies Contain Altered α-Synuclein in Brains of Many Familial Alzheimer's Disease Patients with Mutations in Presenilin and Amyloid Precursor Protein Genes

    Carol F. Lippa;Hideo Fujiwara;David M.A. Mann;Benoit Giasson

  • Circadian clock proteins regulate neuronal redox homeostasis and neurodegeneration

    Erik S. Musiek;Miranda M. Lim;Guangrui Yang;Adam Q. Bauer

  • Induction of α-Synuclein Aggregation by Intracellular Nitrative Insult

    Evgenia Paxinou;Qiping Chen;Marie Weisse;Benoit I. Giasson

  • A Multicenter Study of Glucocerebrosidase Mutations in Dementia With Lewy Bodies

    Michael A. Nalls;Raquel Duran;Grisel Lopez;Marzena Kurzawa-Akanbi

  • The E46K Mutation in α-Synuclein Increases Amyloid Fibril Formation

    Eric A. Greenbaum;Charles L. Graves;Amanda J. Mishizen-Eberz;Michael A. Lupoli

  • Role of α-Synuclein Carboxy-Terminus on Fibril Formation in Vitro†

    Ian V. J. Murray;Benoit I. Giasson;Shawn M. Quinn;Vishwanath Koppaka

  • Novel antibodies to synuclein show abundant striatal pathology in Lewy body diseases

    John E. Duda;Benoit I. Giasson;Meghann E. Mabon;Virginia M.-Y. Lee

  • Misfolded proteinase K–resistant hyperphosphorylated α-synuclein in aged transgenic mice with locomotor deterioration and in human α-synucleinopathies

    Manuela Neumann;Philipp J. Kahle;Benoit I. Giasson;Laurence Ozmen

  • The relationship between oxidative/nitrative stress and pathological inclusions in Alzheimer's and Parkinson's diseases.

    Benoit I. Giasson;Harry Ischiropoulos;Virginia M.-Y. Lee;John Q. Trojanowski

  • Mouse Model of Multiple System Atrophy α-Synuclein Expression in Oligodendrocytes Causes Glial and Neuronal Degeneration

    Ikuru Yazawa;Benoit I. Giasson;Ryogen Sasaki;Bin Zhang

  • Up-regulation of protein chaperones preserves viability of cells expressing toxic Cu/Zn-superoxide dismutase mutants associated with amyotrophic lateral sclerosis

    Wendy Bruening;Josée Roy;Benoit Giasson;Denise A Figlewicz

  • Widespread nitration of pathological inclusions in neurodegenerative synucleinopathies.

    John E. Duda;Benoit I. Giasson;Qiping Chen;Tamar L. Gur

  • Dityrosine cross-linking promotes formation of stable α-synuclein polymers

    Benoit I. Giasson;Jose M. Souza;Qiping Chen;Harry Ischiropoulos

Frequent Co-Authors

Virginia M.-Y. Lee
Virginia M.-Y. Lee University of Pennsylvania
John Q. Trojanowski
John Q. Trojanowski University of Pennsylvania
Todd E. Golde
Todd E. Golde Emory University
Harry Ischiropoulos
Harry Ischiropoulos Children's Hospital of Philadelphia
John E. Duda
John E. Duda University of Pennsylvania
David R. Borchelt
David R. Borchelt University of Florida
Pedro E. Cruz
Pedro E. Cruz University of Florida
Howard I. Hurtig
Howard I. Hurtig University of Pennsylvania
Ellen Sidransky
Ellen Sidransky National Institutes of Health

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