D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 65 Citations 20,384 138 World Ranking 3953 National Ranking 1991

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • DNA

Benoit I. Giasson mainly investigates Alpha-synuclein, Pathology, Lewy body, Cell biology and Biochemistry. His work carried out in the field of Alpha-synuclein brings together such families of science as Protein structure, Immunoelectron microscopy, Cytoplasmic inclusion and Central nervous system. His Pathology research focuses on subjects like Mutation, which are linked to Immunology.

His studies in Lewy body integrate themes in fields like Alzheimer's disease, Dementia with Lewy bodies, Central nervous system disease and Synucleinopathies. He combines subjects such as Oxidative stress, Immunogold labelling and Wild type, Mutant with his study of Cell biology. His Biochemistry study combines topics in areas such as α synuclein and Pathogenesis.

His most cited work include:

  • Oxidative Damage Linked to Neurodegeneration by Selective α-Synuclein Nitration in Synucleinopathy Lesions (1313 citations)
  • Neuronal α-Synucleinopathy with Severe Movement Disorder in Mice Expressing A53T Human α-Synuclein (911 citations)
  • A Hydrophobic Stretch of 12 Amino Acid Residues in the Middle of α-Synuclein Is Essential for Filament Assembly (694 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Cell biology, Alpha-synuclein, Pathology, Synucleinopathies and Biochemistry. His Cell biology research includes elements of Fibril and Neurodegeneration, Tauopathy. His work is dedicated to discovering how Neurodegeneration, Neuroscience are connected with Parkinsonism and other disciplines.

His Alpha-synuclein study also includes

  • Amyloid that connect with fields like Protein aggregation,
  • Mutation together with Mutant and Oxidative stress. The various areas that he examines in his Pathology study include Genetically modified mouse and Central nervous system. His Synucleinopathies research includes themes of Cytoplasmic inclusion, Synuclein and Neurodegeneration with brain iron accumulation.

He most often published in these fields:

  • Cell biology (33.02%)
  • Alpha-synuclein (31.13%)
  • Pathology (28.30%)

What were the highlights of his more recent work (between 2018-2021)?

  • Cell biology (33.02%)
  • Tauopathy (11.79%)
  • Pathology (28.30%)

In recent papers he was focusing on the following fields of study:

Benoit I. Giasson mostly deals with Cell biology, Tauopathy, Pathology, Neurodegeneration and Neuroscience. His Cell biology study focuses on Phosphorylation in particular. He interconnects Neuropil and Neurology in the investigation of issues within Pathology.

The study incorporates disciplines such as Lewy body and Senile plaques in addition to Neurodegeneration. His Lewy body study incorporates themes from Proteostasis and Amyloid. His Neuroscience research incorporates themes from Loss function and Disease.

Between 2018 and 2021, his most popular works were:

  • MAPT mutations, tauopathy, and mechanisms of neurodegeneration. (41 citations)
  • α-Synuclein and astrocytes: tracing the pathways from homeostasis to neurodegeneration in Lewy body disease. (37 citations)
  • Endogenous oligodendroglial alpha-synuclein and TPPP/p25α orchestrate alpha-synuclein pathology in experimental multiple system atrophy models (25 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

Benoit I. Giasson mainly investigates Neurodegeneration, Lewy body, Phosphorylation, Pathology and Tauopathy. His study in Neurodegeneration is interdisciplinary in nature, drawing from both Neuroscience and Senile plaques. His Phosphorylation study introduces a deeper knowledge of Cell biology.

In his research, Inhibitory postsynaptic potential, Serine and In vivo is intimately related to Tau protein, which falls under the overarching field of Cell biology. He mostly deals with Synucleinopathies in his studies of Pathology. His Tauopathy research incorporates elements of Mutation, Protein aggregation, Parkinsonism and Frontotemporal dementia.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Oxidative Damage Linked to Neurodegeneration by Selective α-Synuclein Nitration in Synucleinopathy Lesions

Benoit I. Giasson;John E. Duda;Ian V. J. Murray;Qiping Chen.
Science (2000)

1759 Citations

Neuronal α-Synucleinopathy with Severe Movement Disorder in Mice Expressing A53T Human α-Synuclein

Benoit I. Giasson;John E. Duda;John E. Duda;Shawn M. Quinn;Bin Zhang.
Neuron (2002)

1139 Citations

Initiation and synergistic fibrillization of tau and alpha-synuclein.

Benoit I. Giasson;Mark S. Forman;Mark S. Forman;Makoto Higuchi;Makoto Higuchi;Lawrence I. Golbe;Lawrence I. Golbe.
Science (2003)

1015 Citations

A Hydrophobic Stretch of 12 Amino Acid Residues in the Middle of α-Synuclein Is Essential for Filament Assembly

Benoit I. Giasson;Ian V.J. Murray;John Q. Trojanowski;Virginia M.-Y. Lee.
Journal of Biological Chemistry (2001)

987 Citations

Mutant and Wild Type Human α-Synucleins Assemble into Elongated Filaments with Distinct Morphologies in Vitro

Benoit I. Giasson;Kunihiro Uryu;John Q. Trojanowski;Virginia M.-Y Lee.
Journal of Biological Chemistry (1999)

706 Citations

Dityrosine cross-linking promotes formation of stable alpha -synuclein polymers. Implication of nitrative and oxidative stress in the pathogenesis of neurodegenerative synucleinopathies.

José M. Souza;José M. Souza;Benoit I. Giasson;Qiping Chen;Virginia M.-Y. Lee.
Journal of Biological Chemistry (2000)

674 Citations

Glial cytoplasmic inclusions in white matter oligodendrocytes of multiple system atrophy brains contain insoluble α‐synuclein

Pang‐hsien Tu;James E. Galvin;James E. Galvin;Minami Baba;Benoit Giasson.
Annals of Neurology (1998)

639 Citations

Lewy Bodies Contain Altered α-Synuclein in Brains of Many Familial Alzheimer's Disease Patients with Mutations in Presenilin and Amyloid Precursor Protein Genes

Carol F. Lippa;Hideo Fujiwara;David M.A. Mann;Benoit Giasson.
American Journal of Pathology (1998)

509 Citations

Induction of α-Synuclein Aggregation by Intracellular Nitrative Insult

Evgenia Paxinou;Qiping Chen;Marie Weisse;Benoit I. Giasson.
The Journal of Neuroscience (2001)

465 Citations

Novel antibodies to synuclein show abundant striatal pathology in Lewy body diseases

John E. Duda;Benoit I. Giasson;Meghann E. Mabon;Virginia M.-Y. Lee.
Annals of Neurology (2002)

432 Citations

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