Sandra L. Hofmann

Research.com Recognitions

• 2013 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Best Publications

• Mutations in the palmitoyl protein thioesterase gene causing infantile neuronal ceroid lipofuscinosis

  Jouni Vesa;Elina Hellsten;Linda A. Verkruyse;Laura A. Camp

  819
  Citations

• Purification and properties of a palmitoyl-protein thioesterase that cleaves palmitate from H-Ras.

  Laura A. Camp;Sandra L. Hofmann

  416
  Citations

• Disruption of PPT1 or PPT2 causes neuronal ceroid lipofuscinosis in knockout mice

  Praveena Gupta;Abigail A. Soyombo;Armita Atashband;Krystyna E. Wisniewski

  334
  Citations

• Sterol-dependent repression of low density lipoprotein receptor promoter mediated by 16-base pair sequence adjacent to binding site for transcription factor Sp1.

  P A Dawson;S L Hofmann;D R van der Westhuyzen;T C Südhof

  323
  Citations

• Identification and properties of two distinct phosphatidylinositol-specific phospholipase C enzymes from sheep seminal vesicular glands.

  S L Hofmann;P W Majerus

  310
  Citations

• Lysosomal Targeting of Palmitoyl-protein Thioesterase

  Linda A. Verkruyse;Sandra L. Hofmann

  304
  Citations

• Molecular cloning and expression of palmitoyl-protein thioesterase.

  Laura A. Camp;Linda A. Verkruyse;Steven J. Afendis;Clive A. Slaughter

  296
  Citations

• Hydrolysis of polyphosphoinositides by purified sheep seminal vesicle phospholipase C enzymes

  David B. Wilson;Teresa E. Bross;Sandra L. Hofmann;Philip W. Majerus

  271
  Citations

• Overexpression of human low density lipoprotein receptors leads to accelerated catabolism of Lp(a) lipoprotein in transgenic mice

  Sandra L. Hofmann;Dan L. Eaton;Michael S. Brown;Walter J. McConathy

  224
  Citations

• Molecular genetics of palmitoyl-protein thioesterase deficiency in the U.S.

  Amit K. Das;Carlos H R Becerra;Won Yi;Jui Yun Lu

  221
  Citations

• The crystal structure of palmitoyl protein thioesterase 1 and the molecular basis of infantile neuronal ceroid lipofuscinosis.

  John J. Bellizzi;Joanne Widom;Christopher Kemp;Jui Yun Lu

  209
  Citations

• Regional and cellular neuropathology in the palmitoyl protein thioesterase-1 null mutant mouse model of infantile neuronal ceroid lipofuscinosis

  Ellen Bible;Praveena Gupta;Sandra L. Hofmann;Jonathan D. Cooper

  205
  Citations

• Lipid thioesters derived from acylated proteins accumulate in infantile neuronal ceroid lipofuscinosis: correction of the defect in lymphoblasts by recombinant palmitoyl-protein thioesterase.

  Jui Yun Lu;Linda A. Verkruyse;Sandra L. Hofmann

  194
  Citations

• Modulation of phosphatidylinositol-specific phospholipase C activity by phospholipid interactions, diglycerides, and calcium ions.

  S L Hofmann;P W Majerus

  188
  Citations

• Mutations in the Palmitoyl-Protein Thioesterase Gene (PPT; CLN1) Causing Juvenile Neuronal Ceroid Lipofuscinosis with Granular Osmiophilic Deposits

  Hannah M. Mitchison;Sandra L. Hofmann;Carlos H R Becerra;Patricia B. Munroe

  172
  Citations

• The effects of mepacrine and p-bromophenacyl bromide on arachidonic acid release in human platelets☆

  Sandra L. Hofmann;Stephen M. Prescott;Philip W. Majerus

  169
  Citations

• Functional importance of the amino terminus of Gqα

  John R. Hepler;Gloria H. Biddlecome;Christiane Kleuss;Laura A. Camp

  150
  Citations

• DHHC5 Protein Palmitoylates Flotillin-2 and Is Rapidly Degraded on Induction of Neuronal Differentiation in Cultured Cells

  Yi Li;Brent R. Martin;Benjamin F. Cravatt;Sandra L. Hofmann

  145
  Citations

• Overexpression of low density lipoprotein (LDL) receptor eliminates LDL from plasma in transgenic mice.

  Sandra L Hofmann;David W Russell;Michael S Brown;Joseph L Goldstein

  144
  Citations

• Tissue-specific sorting of the human LDL receptor in polarized epithelia of transgenic mice

  Ravindra K. Pathak;Masayuki Yokode;Robert E. Hammer;Sandra L. Hofmann

  144
  Citations