Peter Lobel

Research.com Recognitions

• 2016 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Best Publications

• Identification of HE1 as the Second Gene of Niemann-Pick C Disease

  Saule Naureckiene;David. E. Sleat;David. E. Sleat;Henry Lackland;Anthony Fensom

  989
  Citations

• Association of Mutations in a Lysosomal Protein with Classical Late-Infantile Neuronal Ceroid Lipofuscinosis

  David E. Sleat;Robert J. Donnelly;Henry Lackland;Henry Lackland;Chang Gong Liu

  650
  Citations

• Mannose 6-Phosphate Receptors and Lysosomal Enzyme Targeting

  N. M. Dahms;P. Lobel;Stuart Kornfeld

  647
  Citations

• Genetic evidence for nonredundant functional cooperativity between NPC1 and NPC2 in lipid transport

  David E. Sleat;Jennifer A. Wiseman;Mukarram El-Banna;Sandy M. Price

  422
  Citations

• STRUCTURE OF A CHOLESTEROL-BINDING PROTEIN DEFICIENT IN NIEMANN-PICK TYPE C2 DISEASE

  Natalia Friedland;Heng-Ling Liou;Peter Lobel;Ann M. Stock

  374
  Citations

• Mutations in the cytoplasmic domain of the 275 kd mannose 6-phosphate receptor differentially alter lysosomal enzyme sorting and endocytosis.

  Peter Lobel;Karen Fujimoto;Richard D. Ye;Gareth Griffiths

  350
  Citations

• Proteomics of the Lysosome

  Torben Lübke;Peter Lobel;Peter Lobel;David E. Sleat;David E. Sleat

  337
  Citations

• Activation of Microglia Acidifies Lysosomes and Leads to Degradation of Alzheimer Amyloid Fibrils

  Amitabha Majumdar;Dana Cruz;Nikiya Asamoah;Adina Buxbaum

  300
  Citations

• A mutation in the ovine cathepsin D gene causes a congenital lysosomal storage disease with profound neurodegeneration

  Jaana Tyynelä;Istvan Sohar;David E. Sleat;Rosalie M. Gin

  277
  Citations

• Cloning and sequence analysis of the cation-independent mannose 6-phosphate receptor.

  P. Lobel;N. M. Dahms;Stuart Kornfeld

  269
  Citations

• Structural Basis of Sterol Binding by NPC2, a Lysosomal Protein Deficient in Niemann-Pick Type C2 Disease

  Sujuan Xu;Brian Benoff;Heng-Ling Liou;Peter Lobel

  254
  Citations

• Mechanism of Cholesterol Transfer from the Niemann-Pick Type C2 Protein to Model Membranes Supports a Role in Lysosomal Cholesterol Transport *♦

  Sunita R. Cheruku;Zhi Xu;Roxanne Dutia;Peter Lobel

  245
  Citations

• Mutational Analysis of the Defective Protease in Classic Late-Infantile Neuronal Ceroid Lipofuscinosis, a Neurodegenerative Lysosomal Storage Disorder

  David E. Sleat;Rosalie M. Gin;Istvan Sohar;Krystyna Wisniewski

  207
  Citations

• 46 kd mannose 6-phosphate receptor: Cloning, expression, and homology to the 215 kd mannose 6-phosphate receptor

  Nancy M. Dahms;Peter Lobel;James Breitmeyer;John M. Chirgwin

  198
  Citations

• A Mouse Model of Classical Late-Infantile Neuronal Ceroid Lipofuscinosis Based on Targeted Disruption of the CLN2 Gene Results in a Loss of Tripeptidyl-Peptidase I Activity and Progressive Neurodegeneration

  David E. Sleat;Jennifer A. Wiseman;Mukarram El-Banna;Kwi Hye Kim

  197
  Citations

• The Human CLN2 Protein/Tripeptidyl-Peptidase I Is a Serine Protease That Autoactivates at Acidic pH

  Li Lin;Li Lin;Istvan Sohar;Henry Lackland;Peter Lobel;Peter Lobel

  194
  Citations

• Differential sorting of lysosomal enzymes in mannose 6-phosphate receptor-deficient fibroblasts.

  T Ludwig;H Munier-Lehmann;U Bauer;M Hollinshead

  188
  Citations

• Niemann-Pick Disease Type C: Spectrum of HE1 Mutations and Genotype/Phenotype Correlations in the NPC2 Group

  Gilles Millat;Karim Chikh;Saule Naureckiene;David E. Sleat

  185
  Citations

• Cloning of the bovine 215-kDa cation-independent mannose 6-phosphate receptor.

  Peter Lobel;Nancy M. Dahms;James Breitmeyer;John M. Chirgwin

  182
  Citations

• Intraventricular enzyme replacement improves disease phenotypes in a mouse model of late infantile neuronal ceroid lipofuscinosis

  Michael Chang;Jonathan D Cooper;David E Sleat;David E Sleat;Seng H Cheng

  181
  Citations