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Biology and Biochemistry

D-Index
120
Citations
54644
World Ranking
635
National Ranking
405

Research.com Recognitions

  • 2010 - E.B. Wilson Medal, American Society for Cell Biology
  • 1988 - Fellow of the American Academy of Arts and Sciences
  • 1984 - Member of the National Academy of Medicine (NAM)
  • 1982 - Member of the National Academy of Sciences
  • 1967 - Fellow of the American Association for the Advancement of Science (AAAS)
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Stuart Kornfeld is affiliated with Washington University in St. Louis in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with significant contributions to medicine. Kornfeld's work spans several subfields including molecular biology, physiology, cell biology, infectious diseases, and organic chemistry.

The scientist's main topics of study include cellular transport and secretion, glycosylation and glycoproteins research, lysosomal storage disorders research, calcium signaling and nucleotide metabolism, SARS-CoV-2 and COVID-19 research, lipid membrane structure and behavior, and viral gastroenteritis research and epidemiology.

Frequent publication venues for Kornfeld's research include:

  • Molecular Genetics and Metabolism
  • FEBS Letters
  • Glycobiology
  • Nature Structural & Molecular Biology
  • FEBS Open Bio

Selected recent papers by Stuart Kornfeld include:

  • "A weak COPI binding motif in the cytoplasmic tail of SARS-CoV-2 spike glycoprotein is necessary for its cleavage, glycosylation, and localization" (2021, FEBS Letters)
  • "Cataloging natural sialic acids and other nonulosonic acids (NulOs), and their representation using the Symbol Nomenclature for Glycans" (2023, Glycobiology)
  • "Structure of the human GlcNAc-1-phosphotransferase αβ subunits reveals regulatory mechanism for lysosomal enzyme glycan phosphorylation" (2022, Nature Structural & Molecular Biology)
  • "Inactivation of the three GGA genes in HeLa cells partially compromises lysosomal enzyme sorting" (2020, FEBS Open Bio)
  • "Disease-causing missense mutations within the N-terminal transmembrane domain of GlcNAc-1-phosphotransferase impair endoplasmic reticulum translocation or Golgi retention" (2020, Human Mutation)

Kornfeld collaborates frequently with researchers including Balraj Doray, Benjamin C. Jennings, Wang-Sik Lee, Lin Liu, and Huilin Li.

Throughout their career, Kornfeld has been recognized by multiple professional organizations and awards. Notable honors include:

  • Member of the National Academy of Sciences (1982)
  • Member of the National Academy of Medicine (1984)
  • Fellow of the American Academy of Arts and Sciences (1988)
  • E.B. Wilson Medal from the American Society for Cell Biology (2010)
  • Fellow of the American Association for the Advancement of Science (1967)
  • Member of the Association of American Physicians

Best Publications

  • Assembly of asparagine-linked oligosaccharides.

    Rosalind Kornfeld;Stuart Kornfeld

  • The Biogenesis of Lysosomes

    Stuart Kornfeld;Ira Mellman

  • Structure and function of the mannose 6-phosphate/insulinlike growth factor II receptors.

    Stuart Kornfeld

  • Mannose 6-phosphate receptors: new twists in the tale

    Pradipta Ghosh;Nancy M. Dahms;Stuart Kornfeld

  • Comparative Aspects of Glycoprotein Structure

    R. Kornfeld;Stuart Kornfeld

  • Symbol Nomenclature for Graphical Representations of Glycans.

    Ajit Varki;Richard D. Cummings;Markus Aebi;Nicole H. Packer

  • The mannose 6-phosphate receptor and the biogenesis of lysosomes

    Gareth Griffiths;Bernard Hoflack;Kai Simons;Ira Mellman

  • Characterization of the structural determinants required for the high affinity interaction of asparagine-linked oligosaccharides with immobilized Phaseolus vulgaris leukoagglutinating and erythroagglutinating lectins.

    R D Cummings;S Kornfeld

  • Fractionation of asparagine-linked oligosaccharides by serial lectin-Agarose affinity chromatography. A rapid, sensitive, and specific technique.

    R D Cummings;S Kornfeld

  • Trafficking of lysosomal enzymes.

    Stuart Kornfeld

  • Mannose 6-Phosphate Receptors and Lysosomal Enzyme Targeting

    N. M. Dahms;P. Lobel;Stuart Kornfeld

  • Trafficking of lysosomal enzymes in normal and disease states.

    Stuart Kornfeld

  • The synthesis of complex-type oligosaccharides. I. Structure of the lipid-linked oligosaccharide precursor of the complex-type oligosaccharides of the vesicular stomatitis virus G protein.

    E. Li;I. Tabas;S. Kornfeld

  • Structure of the carbohydrate units of IgA1 immunoglobulin. II. Structure of the O-glycosidically linked oligosaccharide units.

    Jacques Baenziger;Stuart Kornfeld

  • Biosynthesis of N- and O-linked oligosaccharides of the low density lipoprotein receptor.

    R. D. Cummings;S. Kornfeld;W. J. Schneider;K. K. Hobgood

  • Processing of high mannose oligosaccharides to form complex type oligosaccharides on the newly synthesized polypeptides of the vesicular stomatitis virus G protein and the IgG heavy chain.

    I Tabas;S Schlesinger;S Kornfeld

  • The structure of a phytohemagglutinin receptor site from human erythrocytes.

    Rosalind Kornfeld;Stuart Kornfeld

  • The synthesis of complex-type oligosaccharides. II. Characterization of the processing intermediates in the synthesis of the complex oligosaccharide units of the vesicular stomatitis virus G protein.

    Stuart Kornfeld;E. Li;I. Tabas

  • A molecular sensor that allows a gut commensal to control its nutrient foundation in a competitive ecosystem (host-microbial cross-talkygerm-free miceyBacteroides thetaiotaomicronytranscriptional repressorsyepithelial fucosylated glycan synthesis)

    Lora V. Hooper;Jian Xu;Per G. Falk;T Ore Midtvedt

  • THE BIOGENESIS OF L YSOSOMES

    Stuart Kornfeld;Ira Mellman

Frequent Co-Authors

Ajit Varki
Ajit Varki University of California, San Diego
Marc L. Reitman
Marc L. Reitman National Institute of Diabetes and Digestive and Kidney Diseases
Sondra Schlesinger
Sondra Schlesinger Washington University in St. Louis
Daniel E. Goldberg
Daniel E. Goldberg Washington University in St. Louis
Richard D. Cummings
Richard D. Cummings Harvard Medical School
Linton M. Traub
Linton M. Traub University of Pittsburgh
Peter Vogel
Peter Vogel St. Jude Children's Research Hospital
Luis Glaser
Luis Glaser Washington University in St. Louis
Jacques U. Baenziger
Jacques U. Baenziger Washington University in St. Louis
Peter Lobel
Peter Lobel Rutgers, The State University of New Jersey

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