D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 84 Citations 27,242 236 World Ranking 1431 National Ranking 35

Research.com Recognitions

Awards & Achievements

2012 - Fellow of the Royal Society of Canada Academy of Science

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Internal medicine

James W. Dennis mainly investigates Cell biology, Biochemistry, Glycoprotein, Golgi apparatus and Galectin. He studies Cell biology, focusing on Signal transduction in particular. His Signal transduction study integrates concerns from other disciplines, such as Epidermal growth factor and Cell membrane.

The Biochemistry study combines topics in areas such as Cell culture and Molecular biology. The concepts of his Glycoprotein study are interwoven with issues in Cell signaling and Glycosylation. His Golgi apparatus study combines topics in areas such as Integrin, Endocytosis, Cellular differentiation and Binding site.

His most cited work include:

  • Beta 1-6 branching of Asn-linked oligosaccharides is directly associated with metastasis (807 citations)
  • Negative regulation of T-cell activation and autoimmunity by Mgat5 N -glycosylation (703 citations)
  • Negative regulation of T-cell activation and autoimmunity by Mgat5 N -glycosylation (703 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in Cell biology, Biochemistry, Molecular biology, Glycosylation and Glycoprotein. His Cell biology study incorporates themes from Cancer cell, Endocytosis and Cell growth. James W. Dennis works mostly in the field of Biochemistry, limiting it down to topics relating to Cell culture and, in certain cases, Cancer research and Wheat germ agglutinin.

His Molecular biology research integrates issues from Gene, Mutant, Sialic acid and Chinese hamster ovary cell. The study incorporates disciplines such as Glycolipid and Oligosaccharide in addition to Glycoprotein. The Signal transduction study combines topics in areas such as Receptor, Epidermal growth factor and Cell membrane.

He most often published in these fields:

  • Cell biology (49.69%)
  • Biochemistry (39.13%)
  • Molecular biology (24.53%)

What were the highlights of his more recent work (between 2012-2021)?

  • Cell biology (49.69%)
  • Biochemistry (39.13%)
  • Metabolism (8.07%)

In recent papers he was focusing on the following fields of study:

Cell biology, Biochemistry, Metabolism, Glycosylation and Signal transducing adaptor protein are his primary areas of study. Focal adhesion is the focus of his Cell biology research. His studies in Golgi apparatus, Glycolysis, In vitro and Gene knockdown are all subfields of Biochemistry research.

Golgi apparatus is often connected to Glycan in his work. He has included themes like Plasma protein binding, Chinese hamster ovary cell, Galectin, Baby hamster kidney cell and Glycoprotein in his Glycosylation study. His Signal transducing adaptor protein research is multidisciplinary, relying on both Biophysics, Scaffold protein, Receptor tyrosine kinase and Protein tyrosine phosphatase.

Between 2012 and 2021, his most popular works were:

  • Temporal regulation of EGF signalling networks by the scaffold protein Shc1 (183 citations)
  • Temporal regulation of EGF signalling networks by the scaffold protein Shc1 (183 citations)
  • The galectin lattice at a glance. (151 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Internal medicine

His primary areas of study are Cell biology, Biochemistry, Metabolism, Golgi apparatus and Biosynthesis. His Cell biology study combines topics from a wide range of disciplines, such as Cancer cell and Cancer research. His study in Biochemistry focuses on Glycosylation in particular.

His Glycosylation research incorporates elements of Galectin, Catabolism, Cytosol, Endocytosis and NAD+ kinase. The Metabolism study which covers Metabolite that intersects with Cell growth, Intracellular, Tandem mass spectrometry, Amino acid and Sample preparation. His biological study spans a wide range of topics, including Transmembrane protein, Integrin and Glycoprotein, Glycan.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Beta 1-6 branching of Asn-linked oligosaccharides is directly associated with metastasis

James W. Dennis;Suzanne Laferte;Carol Waghorne;Martin L. Breitman.
Science (1987)

1118 Citations

Negative regulation of T-cell activation and autoimmunity by Mgat5 N -glycosylation

Michael Demetriou;Maria Granovsky;Sue Quaggin;James W. Dennis;James W. Dennis.
Nature (2001)

914 Citations

Glycoprotein glycosylation and cancer progression

James W. Dennis;Maria Granovsky;Maria Granovsky;Charles E. Warren.
Biochimica et Biophysica Acta (1999)

842 Citations

Complex N-Glycan Number and Degree of Branching Cooperate to Regulate Cell Proliferation and Differentiation

Ken S. Lau;Ken S. Lau;Emily A. Partridge;Emily A. Partridge;Ani Grigorian;Cristina I. Silvescu.
Cell (2007)

788 Citations

Regulation of cytokine receptors by Golgi N-glycan processing and endocytosis.

Emily A. Partridge;Christine Le Roy;Gianni M. Di Guglielmo;Judy Pawling.
Science (2004)

726 Citations

Suppression of tumor growth and metastasis in Mgat5-deficient mice.

Maria Granovsky;Maria Granovsky;Jimmie Fata;Judy Pawling;William J. Muller.
Nature Medicine (2000)

567 Citations

Inhibitors of carbohydrate processing: A new class of anticancer agents.

Paul E Goss;Michael A. Baker;Jeremy P. Carver;James W. Dennis.
Clinical Cancer Research (1995)

487 Citations

β1–6 Branched Oligosaccharides as a Marker of Tumor Progression in Human Breast and Colon Neoplasia

B. Fernandes;U. Sagman;M. Auger;M. Demetrio.
Cancer Research (1991)

479 Citations

Protein glycosylation in development and disease.

James W. Dennis;Maria Granovsky;Maria Granovsky;Charles E. Warren.
BioEssays (1999)

469 Citations

Interferon alfacon-1 plus corticosteroids in severe acute respiratory syndrome: a preliminary study.

Mona R. Loutfy;Lawrence M. Blatt;Katharine A. Siminovitch;Sarah Ward.
JAMA (2003)

435 Citations

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