2012 - Fellow of the Royal Society of Canada Academy of Science
James W. Dennis mainly investigates Cell biology, Biochemistry, Glycoprotein, Golgi apparatus and Galectin. He studies Cell biology, focusing on Signal transduction in particular. His Signal transduction study integrates concerns from other disciplines, such as Epidermal growth factor and Cell membrane.
The Biochemistry study combines topics in areas such as Cell culture and Molecular biology. The concepts of his Glycoprotein study are interwoven with issues in Cell signaling and Glycosylation. His Golgi apparatus study combines topics in areas such as Integrin, Endocytosis, Cellular differentiation and Binding site.
His primary scientific interests are in Cell biology, Biochemistry, Molecular biology, Glycosylation and Glycoprotein. His Cell biology study incorporates themes from Cancer cell, Endocytosis and Cell growth. James W. Dennis works mostly in the field of Biochemistry, limiting it down to topics relating to Cell culture and, in certain cases, Cancer research and Wheat germ agglutinin.
His Molecular biology research integrates issues from Gene, Mutant, Sialic acid and Chinese hamster ovary cell. The study incorporates disciplines such as Glycolipid and Oligosaccharide in addition to Glycoprotein. The Signal transduction study combines topics in areas such as Receptor, Epidermal growth factor and Cell membrane.
Cell biology, Biochemistry, Metabolism, Glycosylation and Signal transducing adaptor protein are his primary areas of study. Focal adhesion is the focus of his Cell biology research. His studies in Golgi apparatus, Glycolysis, In vitro and Gene knockdown are all subfields of Biochemistry research.
Golgi apparatus is often connected to Glycan in his work. He has included themes like Plasma protein binding, Chinese hamster ovary cell, Galectin, Baby hamster kidney cell and Glycoprotein in his Glycosylation study. His Signal transducing adaptor protein research is multidisciplinary, relying on both Biophysics, Scaffold protein, Receptor tyrosine kinase and Protein tyrosine phosphatase.
His primary areas of study are Cell biology, Biochemistry, Metabolism, Golgi apparatus and Biosynthesis. His Cell biology study combines topics from a wide range of disciplines, such as Cancer cell and Cancer research. His study in Biochemistry focuses on Glycosylation in particular.
His Glycosylation research incorporates elements of Galectin, Catabolism, Cytosol, Endocytosis and NAD+ kinase. The Metabolism study which covers Metabolite that intersects with Cell growth, Intracellular, Tandem mass spectrometry, Amino acid and Sample preparation. His biological study spans a wide range of topics, including Transmembrane protein, Integrin and Glycoprotein, Glycan.
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Beta 1-6 branching of Asn-linked oligosaccharides is directly associated with metastasis
James W. Dennis;Suzanne Laferte;Carol Waghorne;Martin L. Breitman.
Science (1987)
Negative regulation of T-cell activation and autoimmunity by Mgat5 N -glycosylation
Michael Demetriou;Maria Granovsky;Sue Quaggin;James W. Dennis;James W. Dennis.
Nature (2001)
Glycoprotein glycosylation and cancer progression
James W. Dennis;Maria Granovsky;Maria Granovsky;Charles E. Warren.
Biochimica et Biophysica Acta (1999)
Complex N-Glycan Number and Degree of Branching Cooperate to Regulate Cell Proliferation and Differentiation
Ken S. Lau;Ken S. Lau;Emily A. Partridge;Emily A. Partridge;Ani Grigorian;Cristina I. Silvescu.
Cell (2007)
Regulation of cytokine receptors by Golgi N-glycan processing and endocytosis.
Emily A. Partridge;Christine Le Roy;Gianni M. Di Guglielmo;Judy Pawling.
Science (2004)
Suppression of tumor growth and metastasis in Mgat5-deficient mice.
Maria Granovsky;Maria Granovsky;Jimmie Fata;Judy Pawling;William J. Muller.
Nature Medicine (2000)
Inhibitors of carbohydrate processing: A new class of anticancer agents.
Paul E Goss;Michael A. Baker;Jeremy P. Carver;James W. Dennis.
Clinical Cancer Research (1995)
β1–6 Branched Oligosaccharides as a Marker of Tumor Progression in Human Breast and Colon Neoplasia
B. Fernandes;U. Sagman;M. Auger;M. Demetrio.
Cancer Research (1991)
Protein glycosylation in development and disease.
James W. Dennis;Maria Granovsky;Maria Granovsky;Charles E. Warren.
BioEssays (1999)
Interferon alfacon-1 plus corticosteroids in severe acute respiratory syndrome: a preliminary study.
Mona R. Loutfy;Lawrence M. Blatt;Katharine A. Siminovitch;Sarah Ward.
JAMA (2003)
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