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Chemistry

D-Index
75
Citations
15620
World Ranking
4562
National Ranking
1437

Overview

Yehia Mechref is affiliated with Texas Tech University in the United States. Their research primarily spans the fields of biochemistry, genetics, and molecular biology, with significant contributions also in medicine and chemistry. Mechref's work delves deeply into molecular biology, spectroscopy, organic chemistry, neurology, and epidemiology, reflecting an interdisciplinary approach within the life sciences and analytical chemistry domains.

The scientist's research topics include glycosylation and glycoproteins research, carbohydrate chemistry and synthesis, advanced proteomics techniques and applications, and mass spectrometry techniques and applications. Additional areas of focus encompass analytical chemistry and chromatography, proteoglycans and glycosaminoglycans research, as well as traumatic brain injury and neurovascular disturbances.

Yehia Mechref has published extensively in several scientific venues. Frequent publication outlets comprise:

  • Biomolecules
  • Journal of Proteome Research
  • Analytical Chemistry
  • Methods in Molecular Biology
  • Journal of Pharmacology and Experimental Therapeutics

Among recent notable publications are:

  • "Community evaluation of glycoproteomics informatics solutions reveals high-performance search strategies for serum glycopeptide analysis" (2021) in Nature Methods
  • "MS-based glycomics and glycoproteomics methods enabling isomeric characterization" (2021) in Mass Spectrometry Reviews
  • "Glycomics and glycoproteomics: Approaches to address isomeric separation of glycans and glycopeptides" (2020) in Journal of Separation Science
  • "Circulating Brain Injury Exosomal Proteins following Moderate-to-Severe Traumatic Brain Injury: Temporal Profile, Outcome Prediction and Therapy Implications" (2020) in Cells
  • "Browning white adipose tissue using adipose stromal cell-targeted resveratrol-loaded nanoparticles for combating obesity" (2021) in Journal of Controlled Release

Mechref collaborates frequently with a range of researchers. Regular coauthors include:

  • Firas Kobeissy
  • Cristian D. Gutierrez Reyes
  • Mona Goli
  • Wenjing Peng
  • Sherifdeen Onigbinde

The profile of Yehia Mechref highlights a breadth of work in biochemical and analytical techniques, particularly focusing on glycobiology and proteomics. Their contributions span experimental and methodological advancements as well as applications related to neurological injury and disease.

Best Publications

  • Comparison of the methods for profiling glycoprotein glycans--HUPO Human Disease Glycomics/Proteome Initiative multi-institutional study.

    Yoshinao Wada;Parastoo Azadi;Catherine E. Costello;Anne Dell

  • Structural investigations of glycoconjugates at high sensitivity.

    Yehia Mechref;Milos V. Novotny

  • Solid-phase permethylation of glycans for mass spectrometric analysis

    Pilsoo Kang;Yehia Mechref;Iveta Klouckova;Milos V. Novotny

  • Microscale nonreductive release of O-linked glycans for subsequent analysis through MALDI mass spectrometry and capillary electrophoresis.

    Yunping Huang;Yehia Mechref;Milos V. Novotny

  • Breast cancer diagnosis and prognosis through quantitative measurements of serum glycan profiles.

    Zuzana Kyselova;Yehia Mechref;Pilsoo Kang;John A Goetz

  • Alterations in the serum glycome due to metastatic prostate cancer.

    Zuzana Kyselova;Yehia Mechref;Mohammad M. Al Bataineh;Lacey E. Dobrolecki

  • High-throughput solid-phase permethylation of glycans prior to mass spectrometry.

    Pilsoo Kang;Yehia Mechref;Milos V. Novotny

  • Structural characterization of oligosaccharides using MALDI-TOF/TOF tandem mass spectrometry

    Yehia Mechref;Milos V. Novotny;Cheni Krishnan

  • N-linked Glycan Structures and Their Expressions Change in the Blood Sera of Ovarian Cancer Patients

    William R. Alley;Jacqueline A. Vasseur;John A. Goetz;Martin Svoboda

  • Comparative glycomic mapping through quantitative permethylation and stable-isotope labeling.

    Pilsoo Kang;Yehia Mechref;Zuzana Kyselova;John A. Goetz

  • Chip-based Reversed-phase Liquid Chromatography−Mass Spectrometry of Permethylated N-Linked Glycans: A Potential Methodology for Cancer-biomarker Discovery

    William R. Alley;Milan Madera;Yehia Mechref;Milos V. Novotny

  • Characterization of glycopeptides by combining collision-induced dissociation and electron-transfer dissociation mass spectrometry data.

    William R. Alley;Yehia Mechref;Milos V. Novotny

  • Identifying cancer biomarkers by mass spectrometry-based glycomics

    Yehia Mechref;Yunli Hu;Aldo Garcia;Ahmed Hussein

  • A cancer-associated PCNA expressed in breast cancer has implications as a potential biomarker

    Linda H. Malkas;Brittney Shea Herbert;Waleed Abdel-Aziz;Lacey E. Dobrolecki

  • Profiling of human serum glycans associated with liver cancer and cirrhosis by IMS-MS.

    D. Isailovic;R. T. Kurulugama;M. D. Plasencia;S. T. Stokes

  • Characterizing protein glycosylation sites through higher‐energy C‐trap dissociation

    Zaneer M. Segu;Yehia Mechref

  • Resolving and assigning N-linked glycan structural isomers from ovalbumin by IMS-MS.

    Manolo D. Plasencia;Dragan Isailovic;Samuel I. Merenbloom;Yehia Mechref

  • Combining lectin microcolumns with high-resolution separation techniques for enrichment of glycoproteins and glycopeptides.

    Milan Madera;Yehia Mechref;Milos V. Novotny

  • Detection of hepatocellular carcinoma using glycomic analysis.

    Radoslav Goldman;Habtom W. Ressom;Rency S. Varghese;Lenka Goldman

  • Characterization of isomeric glycan structures by LC-MS/MS.

    Lucas Veillon;Yifan Huang;Wenjing Peng;Xue Dong

  • Mass Spectrometric Mapping and Sequencing of N-Linked Oligosaccharides Derived from Submicrogram Amounts of Glycoproteins

    Yehia Mechref;Milos V. Novotny

  • Physico‐chemical characteristics and total quality of five date varieties grown in the United Arab Emirates†

    Baraem Ismail;Imad Haffar;Riad Baalbaki;Yehia Mechref

  • Glycomic analysis by capillary electrophoresis-mass spectrometry.

    Yehia Mechref;Milos V. Novotny

Frequent Co-Authors

Milos V. Novotny
Milos V. Novotny Indiana University
Haixu Tang
Haixu Tang Indiana University
Ziad El Rassi
Ziad El Rassi Oklahoma State University
David E. Clemmer
David E. Clemmer Indiana University
Paul W. Paré
Paul W. Paré Texas Tech University
Nicolle H. Packer
Nicolle H. Packer Macquarie University
James P. Reilly
James P. Reilly Indiana University
Daniel Kolarich
Daniel Kolarich Griffith University
Hans Lischka
Hans Lischka Texas Tech University
Koichi Kato
Koichi Kato National Institutes of Natural Sciences

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